Carbachol

Description

Carbachol is used for reducing the intensity of increased fluid pressure inside the eye (intraocular hypertension) in the first 24 hours after cataract surgery and for the production of miosis (excessive constriction of the pupil of the eye) during ophthalmic surgeries. The topical ophthalmic solution of this medicine (eye drops) is used to treat glaucoma (open and narrow-angle), a condition that may eventually lead to vision loss

Side effects

Major & minor side effects for Carbachol

  • Blurred vision
  • Changes in vision
  • Eye pain
  • Eye swelling
  • Headache
  • Dizziness

Uses of Carbachol

What is it prescribed for?

  • Intraocular hypertension
  • Production of miosis
  • Glaucoma
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 10 to 20 minutes for ophthalmic instillation and 2-3 minutes for intraocular injection.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 4 to 8 hours for ophthalmic instillation and 24 hours for intraocular injection.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving/using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving/using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to carbachol or any other inactive ingredients present along with this medicine.

Uveitis

This medicine is not recommended for use in patients suffering from uveitis since it may worsen the patient's condition.

Acute iritis

This medicine is not recommended for use in patients with acute iritis since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving/using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving/using this medicine.
General warnings

Asthma

This medicine should be used with caution in patients with asthma due to the risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Peptic Ulcer

This medicine should be used with caution in patients with peptic ulcer disease due to the risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Acute heart failure

This medicine should be used with caution in patients with acute heart failure due to the risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Corneal abrasion

This medicine should be used with caution in patients with corneal abrasion due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Urinary tract obstruction

This medicine should be used with caution in patients with urinary tract obstruction due to the risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Hyperthyroidism

This medicine should be used with caution in patients with hyperthyroidism (an overactive thyroid) due to the risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Use in Children

This medicine is not recommended for use in children less than 18 years of age since the safety and efficacy of use are not clinically established.

Driving or operating machines

Use of this medicine may cause symptoms such as blurred vision or visual disturbances in some patients. If you experience any of these symptoms, it is advised that you do not perform any activities such as driving a vehicle or operating machinery until your symptoms clear.

Contact lens

Based on the severity of your symptoms, your doctor may advise you to avoid the use of contact lenses. If you are allowed to use contact lenses, remove them prior to the administration of the topical ophthalmic form of this medicine (eye drops). They can be reinserted 15 minutes post administration.

Missed Dose

Eye drops: Administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one. Injection: Since this medicine is administered by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Eye drops: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amitriptyline

Risperidone

Atropine

Nortriptyline

Azatadine

Clozapine

Imipramine

Diphenhydramine

Acrivastine

Disease interactions

Retinal detachment

This medicine should be used with caution in patients with risk factors for retinal detachment such as old age, retinal degenerative changes or other retinal disorders, aphakia, prior cataract extraction, or a history of severe myopia or retinal detachment due to the increased risk of retinal detachment. Fundus examination is advised in all patients before starting therapy with this medicine. Replacement with a suitable alternative may be required based on the clinical condition of the patient.

Cataract

This medicine should be used with caution in patients with or predisposed to cataracts due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Eye drops: Use this medicine exactly as prescribed. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Injection: This medicine is administered by a qualified healthcare professional in the hospital setting. Inform the doctor if you have a known allergy to this medicine. Report to the doctor all your current medicines including herbs and supplements as well as all your medical conditions before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by reducing the fluid pressure inside the eyes as well as reducing the size of the pupil.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Ophthalmic glaucoma agents, Miotics

Schedule

Schedule H

[Internet]. Pharmaline.co.il. 2018 [cited 20 December 2018]. Available from:

http://www.pharmaline.co.il/images/newsletterregistration/lapidot/2012/16042012/miostatpatient.pdf

[Internet]. Pdf.hres.ca. 2018 [cited 20 December 2018]. Available from:

https://pdf.hres.ca/dpd_pm/00030632.PDF

Carbachol [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 20 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/carbachol

Carbachol - DrugBank [Internet]. Drugbank.ca. 2018 [cited 20 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB00411

Carbachol Eye Drops [Internet]. Goforyourlife.vic.gov.au. 2018 [cited 20 December 2018]. Available from:

http://goforyourlife.vic.gov.au/bhcv2/bhcmed.nsf/ead67cc7ba5c3879ca257e4200114a2d/59d986e64072a207ca257e420011946b?OpenDocument

[Internet]. 2018 [cited 20 December 2018]. Available from:

https://www.medsafe.govt.nz/Consumers/CMI/m/miostat.pdf

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Information on this page was last updated on 22 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.