Calcitonin

Description

Calcitonin is used to treat osteoporosis in women who are at least 5 years past menopause and who are intolerant of or unwilling to use other therapies. It is also used for relieving the pain associated with osteolysis and/or osteopenia (diseases of the bones). The injectable form of calcitonin is also used for the treatment of Paget's disease, some genetic disorders affecting the bones, as well as pain associated with advanced bone cancer.

Side effects

Major & minor side effects for Calcitonin

  • Runny Nose
  • Bleeding from nose
  • Sinus pain
  • Crusts, dryness, redness, or swelling of nose
  • Back pain
  • Joint pain
  • Stomach upset
  • Severe skin rash and hives
  • Difficulty in breathing
  • Difficulty in swallowing
  • Sudden swelling of eyelids, face, throat, tongue
  • Change in taste
  • Nausea or vomiting
  • Dry mouth
  • Increased thirst
  • Shaking and trembling of arms and feet
  • Decrease/loss of hearing
  • Blurred vision
  • Sleep disturbances

Uses of Calcitonin

What is it prescribed for?

  • Postmenopausal osteoporosis
  • Bone pain
  • Paget's disease
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time taken by this medicine to show its effect is subject to vary based on the intended use, the method of administration, and the individual constitution.
  • Duration of effect
    The amount of time for which this medicine remains effective is subject to vary based on the duration of use, the method of administration, and the individual constitution.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to calcitonin or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
General warnings

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you report all your current medicines, including any herbs and supplements, to the doctor before beginning treatment with this medicine.

Hypocalcemia

Use of this medicine may significantly reduce the levels of calcium in the blood. This may cause severe adverse effects such as muscle cramps, seizures, etc. Close monitoring of blood calcium levels may be necessary in some cases. Appropriate supplementation of calcium and vitamin D may be required based on the clinical condition.

Malignancies

Use of this medicine may increase the risk of malignancies (tumors). This risk is especially higher if the medicine is used for a prolonged period of time. Report any unusual signs and symptoms to your doctor immediately. Close monitoring of clinical condition, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Serious allergic reactions

Use of this medicine may cause serious or life-threatening allergic reactions in some patients. It is recommended to perform skin tests prior to initiation of therapy in patients with suspected hypersensitivity (allergy) to calcitonin. Report any unusual symptoms to your doctor immediately. Appropriate corrective measures and replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Regular nasal examinations

Use of this medicine may cause nosebleeds, crusts, dryness, irritation, etc. in some patients. Hence, periodic nasal examinations are recommended during therapy with this medicine.

Antibody formation

Circulating antibodies to calcitonin may develop during the course of treatment with this medicine. This may cause a loss of response to treatment. The possibility of antibody formation should be considered in patients who show an initial response in the early stage but stop responding to the medicine later on. An alternative treatment option should be considered in these cases based on the clinical condition.

Missed Dose

Administer the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose should be skipped. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Cimetidine

Lithium

Disease interactions

Mineral metabolism disorder

This medicine should be used with caution in patients suffering from mineral metabolism disorders such as vitamin D deficiency. Deficiency of vitamin D should be treated prior to initiating treatment with this medicine. An adequate supply of calcium and vitamin D should be ensured via dietary and non-dietary forms of supplementation throughout the course of treatment with this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Administer this medicine exactly as prescribed by the doctor. Do not administer in larger or smaller amounts than prescribed. The nasal spray should be inhaled through the nose. It is recommended to alternate the nostrils during each administration. Appropriate supplementation of calcium and vitamin D is recommended during treatment with this medicine. Report any unusual symptoms to the doctor immediately. Ensure that the course of treatment is completed. Do not stop the use of any medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine prevents the breakdown of bones and increases their density.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Calcitonin

Schedule

Schedule H

[Internet]. Mhra.gov.uk. 2018 [cited 18 September 2018]. Available from:

http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1533269635027.pdf

[Internet]. Torrentian.com. 2018 [cited 18 September 2018]. Available from:

http://www.torrentian.com/pisheet/Upload/PI_Sheet/1948.pdf

[Internet]. Accessdata.fda.gov. 2018 [cited 18 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021406s008lbl.pdf

[Internet]. Parpharm.com. 2018 [cited 18 September 2018]. Available from:

https://www.parpharm.com/products/assets/pdf/Calcitonin-Spray.pdf

Salmon Calcitonin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 18 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00017

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Information on this page was last updated on 19 Sep 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.