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Cafirate Injection

Manufactured by: SUN PHARMA LABORATORIES LTD
Composition: Caffeine Citrate
Prescription Required: Yes
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Description

Cafirate Injection is a naturally occurring methylxanthine derivative used in the treatment of apnoea of prematurity in infants; it is a condition characterized by the stoppage of breathing for more than 20 seconds, breathing difficulties, and a low heart rate.

Side effects

Major & minor side effects for Cafirate Injection

  • Feeding intolerance
  • Agitation
  • Chills
  • Coma
  • Confusion
  • Depression
  • Dizziness
  • Decreased urine output
  • Nausea
  • Vomiting
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Cafirate Injection

Onset of action

The amount of time required for this medicine to show its action is not clinically established.

Duration of effect

The amount of time for which this medicine remains active in the body is not clinically established.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit-forming tendencies were reported.

Usage in pregnancy?

Since this medicine is only used for the treatment of premature babies (apnoea of prematurity), pregnancy warnings do not apply.

Usage while breast-feeding?

Since this medicine is only used for the treatment of premature babies (apnoea of prematurity), breastfeeding warnings do not apply.

Substitutes

List of substitutes for Cafirate Injection

Below is the list of medicines, which have the same composition, strength and form as Cafirate Injection, and hence can be used as its substitute.
Apnicaf Injection
Abbott Healthcare Pvt. Ltd.

What is it prescribed for?

Uses of Cafirate Injection

  • Apnoea of prematurity

    This medicine is used in the treatment of apnoea of prematurity, a condition characterized by the stoppage of breathing for more than 20 seconds, breathing difficulties, and a low heart rate.

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When not to use?

Contraindications of Cafirate Injection

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to caffeine or any other inactive ingredients present along with it.

Dosage

  • Missed Dose

    Oral: The missed dose should be given as soon as possible. It is advisable to skip the missed dose if it is already time for the next scheduled dose. Do not use extra medicine to make up for the missed dose. Injection: Since this medicine is administered by a qualified healthcare professional, the likelihood of a missed dose is very low.

  • Overdose

    Oral: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since this medicine is administered by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

  • Cardiovascular disorders

    severe
    This medicine is not recommended for use in patients with a known history of serious cardiac disorders such as severe hypertension, coronary artery disease, heart failure, etc. due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

  • Liver Disease

    severe
    This medicine is not recommended for use in patients with a known history of severe liver impairment due to the increased risk of worsening of the patient's condition. In patients with mild to moderate liver diseases, the medicine should be used with caution. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

  • Seizures

    severe
    This medicine should be used with extreme caution in patients with a known history of seizures due to the increased risk of recurrent seizures. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

  • Peptic ulcer disease

    severe
    This medicine should be used with extreme caution in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Oral form: Administer this medicine regardless of food. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor in case of any undesirable side effects. Do not stop the use of this medicine without consulting your doctor. Injection: This medicine is usually administered by a qualified healthcare professional. Inform the doctor if the patient has an allergy to this medicine. Report to the doctor of all the patient's current medicines and medical conditions before receiving this medicine.

Warnings

Warnings for special population

  • Pregnancy

    - Since this medicine is only used for the treatment of premature babies (apnoea of prematurity), pregnancy warnings do not apply.

  • Breast-feeding

    - Since this medicine is only used for the treatment of premature babies (apnoea of prematurity), breastfeeding warnings do not apply.

General warnings

  • Liver impairment

    - This medicine should be used with caution in patients with liver impairment due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • Renal impairment

    - This medicine should be used with caution in patients with renal impairment due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • Use in pediatrics

    - This medicine should only be used in prematurely born patients whose gestational age is between 28 weeks to 37 weeks.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • Does not cause sleepiness

How it works

This medicine helps the patients to breathe easier.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
CNS stimulants
Schedule
Schedule H

References

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Information on this page was last updated on 4 Apr 2018

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.