Description
Cafirate Injection is a naturally occurring methylxanthine derivative used in the treatment of apnoea of prematurity in infants; it is a condition characterized by the stoppage of breathing for more than 20 seconds, breathing difficulties, and a low heart rate.
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Side effects
Major & minor side effects for Cafirate Injection
- Feeding intolerance
- Agitation
- Chills
- Coma
- Confusion
- Depression
- Dizziness
- Decreased urine output
- Nausea
- Vomiting
Uses of Cafirate Injection
What is it prescribed for?
- Apnoea of prematurity
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Concerns
Commonly asked questions
- Onset of actionThe amount of time required for this medicine to show its action is not clinically established.
- Duration of effectThe amount of time for which this medicine remains active in the body is not clinically established.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit-forming tendencies were reported.
- Usage in pregnancy?Since this medicine is only used for the treatment of premature babies (apnoea of prematurity), pregnancy warnings do not apply.
- Usage while breast-feeding?Since this medicine is only used for the treatment of premature babies (apnoea of prematurity), breastfeeding warnings do not apply.
Allergy
This medicine is not recommended for use in patients with a known allergy to caffeine or any other inactive ingredients present along with it.
Warnings for special population
Pregnancy
Since this medicine is only used for the treatment of premature babies (apnoea of prematurity), pregnancy warnings do not apply.
Breast-feeding
Since this medicine is only used for the treatment of premature babies (apnoea of prematurity), breastfeeding warnings do not apply.
General warnings
Liver impairment
This medicine should be used with caution in patients with liver impairment due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Renal impairment
This medicine should be used with caution in patients with renal impairment due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Use in pediatrics
This medicine should only be used in prematurely born patients whose gestational age is between 28 weeks to 37 weeks.
Missed Dose
Oral: The missed dose should be given as soon as possible. It is advisable to skip the missed dose if it is already time for the next scheduled dose. Do not use extra medicine to make up for the missed dose.
Injection: Since this medicine is administered by a qualified healthcare professional, the likelihood of a missed dose is very low.
Overdose
Oral: Seek emergency medical treatment or contact the doctor in case of an overdose.
Injection: Since this medicine is administered by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Ciprofloxacin
Tizanidine
Duloxetine
Theophylline
Fluvoxamine
Lithium
Disease interactions
Cardiovascular disorders
This medicine is not recommended for use in patients with a known history of serious cardiac disorders such as severe hypertension, coronary artery disease, heart failure, etc. due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.
Liver Disease
This medicine is not recommended for use in patients with a known history of severe liver impairment due to the increased risk of worsening of the patient's condition. In patients with mild to moderate liver diseases, the medicine should be used with caution. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.
Seizures
This medicine should be used with extreme caution in patients with a known history of seizures due to the increased risk of recurrent seizures. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Peptic ulcer disease
This medicine should be used with extreme caution in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Oral form: Administer this medicine regardless of food. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor in case of any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Injection: This medicine is usually administered by a qualified healthcare professional. Inform the doctor if the patient has an allergy to this medicine. Report to the doctor of all the patient's current medicines and medical conditions before receiving this medicine.
Miscelleneous
How it works
This medicine helps the patients to breathe easier.
Legal Status
Classification
Category
CNS stimulants
Schedule
Schedule H
Caffeine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 28 March 2018]. Available from:
[Internet]. 2018 [cited 28 March 2018]. Available from:
[Internet]. 2018 [cited 28 March 2018]. Available from:
[Internet]. 2018 [cited 28 March 2018]. Available from:
DailyMed - Caffeine citrate injection, solution [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 3 April 2018]. Available from:
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