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Buvalor 10 Transdermal Patch

Manufactured byMODI MUNDI PHARMA PVT LTD
Description

Buvalor 10 Transdermal Patch is used in the treatment of severe opioid responsive pain conditions in patients who have not adequately responded to non-opioid analgesics.

Side effects

Major & minor side effects for Buvalor 10 Transdermal Patch

  • Dizziness and Drowsiness
  • Headache
  • Difficulty in breathing
  • Nausea and vomiting
  • Itching, redness or irritation at application site
  • Anxiety and nervousness
  • Watery eyes
  • Back pain
  • Irregular heartbeat
  • Decreased blood pressure
  • Unusual weight gain or loss

Uses of Buvalor 10 Transdermal Patch

What is it prescribed for?

  • Severe pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 7 days after administration of the dose.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    This medicine may be habit-forming.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to buprenorphine or any other ingredients present along with it.

Respiratory depression

This medicine is not recommended for use in patients with respiratory depression due to the increased risk of worsening of the patient's condition.

Monoamine oxidase inhibitors (MAO)

This medicine is not recommended for use in patients receiving Monoamine oxidase inhibitors (MAO) or who had taken them within the last 2 weeks due to the increased risk of serious adverse effects.

Myasthenia gravis

This medicine is not recommended for use in patients with myasthenia gravis, an autoimmune disease of the muscle due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before using this medicine.
General warnings

Drug withdrawal

Abrupt discontinuation of this medicine may cause withdrawal signs and symptoms. A gradual dose reduction is recommended to avoid these reactions.

Hypotension

This medicine may cause a sudden drop in blood pressure. This risk is especially higher in patients with a history of cardiovascular disorders or electrolyte disturbances. Vital signs should be closely monitored, especially during the first few days of therapy. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Driving and operating machinery

This medicine may cause difficulty in concentrating, drowsiness, dizziness, confusion, etc. in some patients. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Infectious diarrhea

This medicine should be used with extreme caution in patients with infectious diarrhea since it may worsen the patient's condition. Close monitoring, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Exposure to heat or sunlight

Avoid exposing the transdermal system application site and the surrounding area to direct sunlight, heaters, electric blankets, or hot tube, etc. Exposure may increase the release of this medicine that may cause adverse effects.

Missed Dose

It is advised to contact the doctor immediately if you miss a dose of this medicine for further details.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Tramadol

Ciprofloxacin

CNS depressants

Rasagiline

Azithromycin

Atenolol

Disease interactions

Impaired gastrointestinal function

This medicine should be used with extreme caution in patients with impaired gastrointestinal motility since it may worsen the patient's condition. Close monitoring, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Liver Disease

This medicine should be used with caution in patients with impaired liver function since it may worsen the patient's condition. Close monitoring of liver function, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Impaired kidney function

This medicine should be used with caution in patients with impaired kidney function since it may worsen the patient's condition. Close monitoring of kidney function, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Acute myocardial infarction

This medicine should be used with caution in patients with a known history of a heart attack due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Intracranial pressure

This medicine should be used with extreme caution in patients with a head injury, intracranial lesions, or increased intracranial pressure due to the increased risk of worsening of the patient's condition. Close monitoring, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Addison's Disease

This medicine should be used with caution in patients with a known history of Addison's disease due to the increased risk of respiratory depression and prolonged CNS depression. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hypothyroidism

This medicine should be used with caution in patients with hypothyroidism (a condition where the thyroid gland does not make enough hormones) due to the increased risk of respiratory depression and prolonged CNS depression. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients with seizure disorders due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Urinary tract obstruction

This medicine should be used with caution in patients with urinary retention, prostatic hypertrophy or urethral stricture due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine acts on certain receptors in the brain and thus reduces the pain. It also works by binding with the opioid receptors in the brain and it has a slowly reversible and prolonged effect on these receptors which enable a minimized need for opioid medications in the addicted patients.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Topical Narcotic analgesics

Schedule

Schedule H1

DailyMed - Buprenorphine patch, extended release [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 10 February 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=36995ce3-b515-447b-baa9-aa14f84060d8

Bunov 10 microgram/h transdermal patch - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 10 February 2020]. Available from:

https://www.medicines.org.uk/emc/product/9798/smpc

Buprenorphine Transdermal Patch: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 10 February 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a613042.html

Buprenorphine - DrugBank [Internet]. Drugbank.ca. 2020 [cited 4 March 2020]. Available from:

https://www.drugbank.ca/drugs/DB00921
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Information on this page was last updated on 4 Mar 2020

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.