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Brinzox-T Eye Drops
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Brinzox-T Eye Drops

Manufactured byAjanta Pharma Ltd.
ContainsBrinzolamide (1 %w/v) + Timolol (0.5 %w/v)
Description
Brinzox-T Eye Drops is a combination medicine used for the treatment of increased eye pressure in patients suffering from open-angle glaucoma or ocular hypertension, conditions which may lead to eventual vision loss. This medicine is not recommended for use in patients less than 18 years of age.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Brinzox-T Eye Drops

  • Blurred vision
  • Dry eyes
  • Skin Rash
  • Redness, soreness, irritation or pain of the eye lid
  • Discharge from eyes
  • Dizziness
  • Double vision
  • Burning or stinging sensation at application site
  • Cataract
  • Headache
  • Increase in blood pressure
  • Infections
  • Itching

Uses of Brinzox-T Eye Drops

What is it prescribed for?

  • Intraocular hypertension
  • Open angle Glaucoma
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 20 to 30 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 12 to 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to brinzolamide, timolol, any other beta-blockers, or any other inactive ingredients present along with these medicines.

Severe renal impairment

This medicine is not recommended for use in patients with severe renal impairment (creatinine clearance less than 30 ml/min) since the safety and efficacy of use are not clinically established for such patients.

Respiratory diseases

This medicine is not recommended for use in patients with a known history of respiratory diseases such as bronchial asthma or severe chronic obstructive pulmonary disease due to the increased risk of worsening of the patient's condition.

Sinus Bradycardia

This medicine is not recommended for use in patients with a known history of sinus bradycardia due to the increased risk of worsening of the patient's condition.

Atrioventricular Block

This medicine is not recommended for use in patients with a known history of second or third degree AV block, not controlled with a pacemaker, due to the increased risk of worsening of the patient's condition.

Overt Cardiac Failure

This medicine is not recommended for use in patients with a known overt cardiac failure due to the increased risk of worsening of the patient's condition.

Cardiogenic shock

This medicine is not recommended for use in patients with a known history of cardiogenic shock due to the increased risk of worsening of the patient's condition.

Hyperchloremic Acidosis

This medicine is not recommended for use in patients with hyperchloremic acidosis since the safety and efficacy of use are not clinically established for such patients.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition.
General warnings

Corneal edema

This medicine should be used with caution since it increases the risk of corneal edema. This risk is especially high in patients with a low number of endothelial cells. Report any eye swelling to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Contact lens

This medicine is not recommended for use if you are wearing soft contact lenses in your eyes. The lens should be removed prior to administration of the eye drops and can be reinserted 15 minutes post administration.

Cardiac Failure

This medicine should be used with extreme caution in patients with a known history of cardiac failure since it may worsen the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Use in pediatrics

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any adverse effects.

Driving or Operating Machines

This medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Administer the missed dose as soon as you remember. It is advisable to skip the missed dose if it is almost time for your next scheduled dose. Do not instill a double dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Epinephrine

Beta blockers

Clonidine

Oral carbonic anhydrase inhibitors

CYP2D6 inhibitors

Disease interactions

Renal Diseases

This medicine should be used with caution in patients with a history of renal diseases due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Diabetes

This medicine should be used with caution in patients with a known history of diabetes due to the increased risk of very low blood sugar levels. You may require a dose adjustment and more frequent monitoring of blood glucose levels to safely use this medicine. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hyperthyroidism

This medicine should be used with caution in patients with a known history of hyperthyroidism since an abrupt withdrawal of therapy may worsen the patient's condition. Therapy should be discontinued gradually over a period of 1 to 2 weeks, when necessary, to decrease this risk. Replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Use this medicine exactly as prescribed. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by reducing the fluid pressure inside the eyes.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Ophthalmic glaucoma agents

Schedule

Schedule H

[Internet]. Medsafe.govt.nz. 2018 [cited 2 April 2018]. Available from:

http://www.medsafe.govt.nz/profs/Datasheet/a/azargaeyedrops.pdf

TGA eBS - Product and Consumer Medicine Information Licence [Internet]. Ebs.tga.gov.au. 2018 [cited 13 July 2018]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-02871-3&d=2018071316114622483

[Internet]. Healthtranslations.vic.gov.au. 2018 [cited 2 April 2018]. Available from:

http://www.healthtranslations.vic.gov.au/bhcv2/bhcmed.nsf/ead67cc7ba5c3879ca257e4200114a2d/7bd84ca85cfc62f2ca257e420011ce55/$FILE/CMI9945.pdf
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Information on this page was last updated on 13 Jul 2018

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.