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Bivamax 250 Injection
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Bivamax 250 Injection

Manufactured byLUPIN LTD
ContainsBivalirudin
Description
Bivamax 250 Injection is used to prevent the formation of blood clots in adults during certain surgical procedures and therapies. This medicine is given along with aspirin and is not recommended for use in patients with acute coronary syndromes (ACS) who are not undergoing PCI (Percutaneous Coronary Intervention) or PTCA (Percutaneous Transluminal Coronary Angioplasty) as the safety and efficacy are not clinically established.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Bivamax 250 Injection

  • Abdominal pain
  • Blurred vision
  • Chest pain or discomfort
  • Arm, back or jaw pain
  • Headache
  • Dizziness
  • Nervousness
  • Shortness of breath
  • Sweating
  • Unusual tiredness or weakness
  • Lightheadedness

Uses of Bivamax 250 Injection

What is it prescribed for?

  • Percutaneous Coronary Intervention
  • Percutaneous Transluminal Coronary Angioplasty
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed immediately after an intravenous administration of the dose.
  • How long do the effects of this medicine last?
    The time duration for which this medicine remains effective is subject to vary based on the intended use, dose strength, and route of administration.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to bivalirudin or any other inactive ingredients present in the formulation.

Bleeding disorder

This medicine is not recommended for use in patients who are suffering from active major bleeding due to the increased risk of worsening of the patient's condition.

Severe kidney impairment

This medicine is not recommended for use in patients suffering from severe kidney disease (GFR < 30 ml/min) and in dialysis-dependent patients due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Hemorrhage and risk factors

Use of this medicine should be initiated only after internal bleeding or hemorrhage and associated risk factors are ruled out. All the underlying causes of bleeding such as peptic ulcer disease, hemophilia, impaired hemostasis, etc. should also be ruled out before the administration of this medicine.

Thrombocytopenia

Use of this medicine may cause low levels of platelets (thrombocytopenia). It is advised to monitor the blood platelet levels at regular intervals while this medicine is being administered. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Use in Elderly

This medicine should be used with extreme caution in the elderly population since the risk of adverse effects is significantly high. Appropriate dose adjustments and frequent clinical monitoring are advised for such patients to safely use this medicine.

Kidney Disease

This medicine should be used with caution in patients having an impairment of normal kidney function due to the increased risk of adverse effects. Appropriate dose adjustments and frequent monitoring of kidney function are recommended for such patients. Replacement with a suitable alternative may be necessary based on the clinical condition.

Intravenous use only

This medicine should be administered through intravenous route only. It is not recommended for intramuscular use since the safety and efficacy of use are not clinically established.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Enoxaparin

Escitalopram

Heparin Topical

Dabigatran

Streptokinase

Ketorolac

Apixaban

Warfarin

Diclofenac

Disease interactions

Kidney Disease

This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of adverse effects. Regular monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in a clinic/hospital by a qualified healthcare professional. It should not be injected into the muscles. It is advised to administer this medicine under the supervision of a doctor in a clinical setup with regular monitoring of blood clotting time and other related parameters. Your doctor may ask you to undergo certain tests to determine the safety of this medicine usage.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by interfering with the normal clotting process and decreases the clot-forming ability of the blood.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Thrombin inhibitors

Schedule

Schedule H

Bivalirudin. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2018 [cited 24 December 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/18449412

Bivalirudin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 24 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Bivalirudin

Bivalirudin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 24 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB00006

[Internet]. Dailymed.nlm.nih.gov. 2018 [cited 24 December 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=911cd48f-01ea-4dec-b30c-95e7e0ea9d2a

Angiomax® (bivalirudin) For Injection [Internet]. Angiomax.com. 2018 [cited 24 December 2018]. Available from:

http://www.angiomax.com/
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Information on this page was last updated on 22 Aug 2019

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