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Betnovate N Cream
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Betnovate N Cream

Manufactured byGLAXOSMITHKLINE PHARMACEUTICALS LTD
ContainsBetamethasone (0.1 %w/w) + Neomycin (0.5 %w/w)
Description
Betnovate N Cream is an antibiotic medicine that consists of Betamethasone and Neomycin. It is used in the treatment of bacterial skin infections. Betnovate N Cream is also sometimes used for the treatment of otitis externa (ear infection), lichen simplex chronicus (thickened and rough skin). It works by relieving redness, swelling, and itching associated with various skin conditions caused by bacteria. Betnovate N Cream may cause some side effects like burning, irritation, itching, and redness at the site of application. Stop using this cream and inform your doctor if these symptoms persist. Avoid using this cream if you are allergic to it. Do not touch or scratch the affected area as it may cause the infection to spread. This cream is known to cause ear damage and kidney damage. Hence, Do not use it unless prescribed by your doctor. Betnovate N Cream is for external use only. Hence, avoid contact with the eyes and mouth. wash immediately with water in case of accidental contact. It should be applied with clean dry hands on the affected areas 1-2 times a day. Wash and dry the affected areas before application. Keep the affected area clean and dry because the presence of water can increase microbial growth. Betnovate N Cream may not be suitable for all people. Inform your doctor if you have other active infections and if you are using other medicines for your pre-existing conditions. If you are pregnant or breastfeeding, consult your doctor before using Betnovate N Cream. It may take several weeks for this medicine to improve your condition. Do not stop using it without consulting your doctor.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Betnovate N Cream

  • Skin rash
  • Skin irritation
  • Redness of skin
  • Burning sensation at the application site
  • Dry or scaly skin
  • Itching of skin

Uses of Betnovate N Cream

What is it prescribed for?

  • Lichen simplex chronicus
  • Psoriasis
  • Lichen planus
  • Eczema
  • Atopic dermatitis
  • Ichthyosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken by Betnovate N Cream to start showing effect is not known.
  • How long do the effects of this medicine last?
    The amount of time for which Betnovate N Cream remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Betnovate N Cream.
  • Can this medicine be taken during pregnancy?
    Although Betnovate N Cream is a topical preparation, if you are pregnant, use this medicine only after consulting your doctor.
  • Can this medicine be taken while breast-feeding?
    Betnovate N Cream is considered safe to be used during breastfeeding. Short-term application of this medicine may not cause any harm to your infant. However, consult your doctor before using this medicine.

Allergy

Avoid using Betnovate N Cream if you are allergic to betamethasone or neomycin. Serious allergic reactions to this medicine are rare. Seek immediate medical attention if you notice any symptoms such as skin rash, hives, redness of the skin, itching, swelling of the face, lips, or tongue, etc.

Active infections

An active infection leads to severe bacterial infections if untreated for a long time. The symptoms are redness, swelling, and pain at the site of infection. Betnovate N Cream is not recommended for use in this condition as it may worsen your skin condition. Consult your doctor for a safer alternative treatment.

Acne vulgaris

Acne is a skin condition in which bacteria grow in the clogged pores on your skin causing blackheads, whiteheads, or pimples. Betnovate N Cream is not effective against the bacteria that cause acne and may even worsen your condition if used. Hence, it is not recommended for use in acne.

Perioral dermatitis

Perioral dermatitis is a rash characterised by pain, redness and swelling of the skin around the mouth. If not treated, it may spread to the nose or eyes. It may result in small pus-filled bumps and peeling of the skin. Betnovate N Cream is not recommended in this condition as it may worsen your skin condition. Consult your doctor for a safer alternative treatment.
Warnings for special population

Pregnancy

Although Betnovate N Cream is a topical preparation, if you are pregnant, use this medicine only after consulting your doctor.

Breast-feeding

Betnovate N Cream is considered safe to be used during breastfeeding. Short-term application of this medicine may not cause any harm to your infant. However, consult your doctor before using this medicine.
General warnings

Use in children

Betnovate N Cream is not recommended for use in children below 1 year of age as the safety and efficacy data is not available. Children below 12 years of age should not use this medicine for more than 5 days due to the increased risk of adrenal suppression (the body does not produce necessary hormones).

External use

Betnovate N Cream is recommended for external use only. Avoid contact with your eyes, mouth, wounds, or broken skin. In case of accidental contact, wash with warm water.

Ototoxicity and nephrotoxicity

Betnovate N Cream should be used with caution and only in the prescribed dose as it is known to cause ototoxicity (damage to the ears and hearing) and nephrotoxicity (kidney damage).

Chronic use

High doses of Betnovate N Cream should not be used for more than 2 weeks due to the increased risk of severe side effects. If required, low doses can be used for the long term only under the supervision of your doctor.

Missed Dose

Apply the missed dose of Betnovate N Cream as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply more quantities at a time to make up for the missed one.

Overdose

An overdose of Betnovate N Cream is not likely to cause severe symptoms unless it is applied for prolonged periods of time in large volumes. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Itraconazole

Disease interactions

Hyperadrenocorticism

Betnovate N Cream when taken for long periods of time lead to Cushing's syndrome (a condition that occurs from exposure to high cortisol levels for a long time). This results in thinning of the skin, easy bruising, acne, muscle weakness fatigue, fluctuating blood sugar levels, bone disorders like osteoporosis and hypertension. Any symptoms like swelling of the face, increase in blood sugar levels should be reported to the doctor immediately.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Apply a thin layer of Betnovate N Cream to the affected area as instructed by the doctor. Finish your entire course of treatment even if your symptoms begin to clear up after a few days. If the symptoms are not resolved within seven days, consult your doctor before continuing the treatment. Do not cover the application site with bandages. Do not apply to broken skin or allow contact with eyes, nose or mouth. Keep away from the reach of children and pets. Do not freeze the medicine. Ensure that unused medicine is disposed of properly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Betamethasone works by preventing the production of prostaglandins, the natural substances that cause redness, itching and swelling in the body. Neomycin kills the bacteria by blocking the production of certain proteins that are required for their growth. Thus, this medicine provides relief from the symptoms of the infection.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Topical steroids, Topical antibiotics

Schedule

Schedule H

Drugs, H., 2021. Betamethasone Topical: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 4 October 2021].

https://medlineplus.gov/druginfo/meds/a682799.html>

Pubchem.ncbi.nlm.nih.gov. 2021. Betamethasone. [online] Available at: < [Accessed 4 June 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Betamethasone>

Drugs, H., 2021. Neomycin Topical: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 4 October 2021].

https://medlineplus.gov/druginfo/meds/a682274.html>

Medicines.org.uk. 2021. Betamethasone valerate/Neomycin sulphate 1 mg/5 mg/g Ointment - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 4 October 2021].

https://www.medicines.org.uk/emc/product/12940/smpc>

Drugs.ncats.io. 2021. NCATS Inxight: Drugs — BETAMETHASONE. [online] Available at: < [Accessed 4 October 2021].

https://drugs.ncats.io/drug/9842X06Q6M>

Pubchem.ncbi.nlm.nih.gov. 2021. Neomycin. [online] Available at: < [Accessed 4 October 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin>
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Information on this page was last updated on 12 Oct 2021

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