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Betnovate-GM Cream

Manufactured byGLAXOSMITHKLINE PHARMACEUTICALS LTD
ContainsBetamethasone (0.1 %w/w) + Gentamicin (0.1 %w/w) + Miconazole (2 %w/w)
Description

Betnovate-GM Cream is a combination medicine which may be used for the treatment of steroid responsive dermatoses associated with superficial bacterial and fungal infections of the skin.

Side effects

Major & minor side effects for Betnovate-GM Cream

  • Skin rash
  • Redness of skin
  • Blisters under the skin
  • Burning or tingling sensation of skin
  • Itchy and dry skin
  • Easy bruising of skin
  • Unusually warm skin
  • Lightening of skin at the area of application

Uses of Betnovate-GM Cream

What is it prescribed for?

  • Steroid responsive skin infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to betamethasone, miconazole, gentamicin, or any other inactive ingredients present along with the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
General warnings

Other medicines

This medicine may interact with a large number of medications and may cause severe adverse effects. Hence, it is advised that you report the use of all your medicines including any herbs and supplements to the doctor before beginning therapy with this medicine.

Chronic use

This medicine should not be used for more than one week unless directed by your doctor, due to the increased risk of severe adverse effects.

External use

This medicine is only recommended for external use. Avoid contact with the mouth, eyes, mucous membranes, cuts, grazes, or wounds.

Defect in vision

Use of this medicine has been sometimes associated with an increase in intraocular pressure and may cause glaucoma or formation of cataract. It should be very carefully administered in patients who have a disease of the eye.

Allergic reactions

This medicine has the potential of causing moderate to severe allergic reactions in the body. Any instance indicative of allergic reactions should be reported to the doctor in the first instance.

Cushing's syndrome

This medicine may cause hypothalamic-pituitary-adrenal (HPA) axis suppression and Cushing's syndrome in patients receiving high doses for a prolonged period. Any symptoms of swelling of the face, increase in the blood glucose levels, etc. should be informed to the doctor on priority. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Missed Dose

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of this medicine is not likely to cause severe symptoms. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Antidiabetic medicines

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Apply a thin layer of the cream to the affected area as instructed by the doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by the doctor. Contact your doctor if symptoms do not improve or resolve after one week of use.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Betamethasone works by decreasing the release of certain substances that cause swelling and irritation of the skin. Gentamicin works by inhibiting the protein synthesis which is essential for the bacteria to grow. Miconazole acts by stopping the production of a certain vital component for the fungi. This results in disruption of the cell membrane formation process and inhibits the growth of the organism.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Topical steroids with anti-infectives, Topical antifungals, Topical agents

Schedule

Schedule H

[Internet]. India-pharma.gsk.com. 2019 [cited 24 April 2019]. Available from:

https://india-pharma.gsk.com/media/701021/betnovate-gm.pdf

Betamethasone - DrugBank [Internet]. Drugbank.ca. 2019 [cited 24 April 2019]. Available from:

https://www.drugbank.ca/drugs/DB00443

Gentamicin - DrugBank [Internet]. Drugbank.ca. 2019 [cited 22 April 2019]. Available from:

https://www.drugbank.ca/drugs/DB00798

Miconazole - DrugBank [Internet]. Drugbank.ca. 2019 [cited 22 April 2019]. Available from:

https://www.drugbank.ca/drugs/DB01110
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Information on this page was last updated on 15 Jul 2019

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