Betamethasone

Description

Betamethasone is similar to the naturally occurring steroidal hormones (hydrocortisone/cortisone) produced by the adrenal glands. It is used to treat internal and external swelling associated with diseases like asthma, colitis, arthritis, severe skin allergies etc. It is also used for other conditions like adrenal hormonal insufficiency, certain types of anemia, cerebral edema etc.

Side effects

Major & minor side effects for Betamethasone

  • Blurred vision
  • Increased appetite
  • Indigestion
  • Anxiety and nervousness
  • Skin itch
  • Drying and cracking of skin
  • Acne
  • Change in skin color
  • Persistent infections
  • Irregular menstrual periods
  • Depression
  • Growth retardation in children
  • Hoarseness of voice

Uses of Betamethasone

What is it prescribed for?

  • Allergy and inflammation
  • Joint inflammation
  • Eye inflammation
  • Skin disorders
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within a few minutes after oral administration as it is rapidly absorbed from the gastrointestinal tract. It is subject to vary depending on the route of administration.
  • Duration of effect
    The time duration for which this medicine remains effective is subject to vary depending on the form and route of administration.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    Use of this medicine during pregnancy is not recommended unless absolutely necessary and the benefits outweigh the risks. Consult your doctor before using this medicine.
  • Usage while breast-feeding?
    Use of this medicine while breastfeeding is not recommended. However, if it absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.

Allergy

This medicine is not recommended for use if you have a known history of allergy to it or any other medicine belonging to the category of corticosteroids.

Systemic Fungal Infection

This medicine is not recommended for use if you have a fungal infection affecting an internal organ/organs in the body.

Active untreated infection

This medicine is not recommended for use in patients suffering from any serious infection and is yet to receive any treatment for the same.
Warnings for special population

Pregnancy

Use of this medicine during pregnancy is not recommended unless absolutely necessary and the benefits outweigh the risks. Consult your doctor before using this medicine.

Breast-feeding

Use of this medicine while breastfeeding is not recommended. However, if it absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.
General warnings

Other medications

This medicine may interact with any medicine that you might be possible taking. Report the use of all medicines including supplement and herbs to the doctor to ensure safe and effective use of this medicine.

Allergic reactions

This medicine has the potential of causing moderate to a severe allergic reaction in the body. Any instance indicative of allergic reactions should be reported to the doctor in the first instance.

Other diseases

This medicine should be used with caution if the patient is suffering from diseases like cirrhosis, diverticulitis, myasthenia gravis, peptic ulcer disease, kidney diseases etc. Report the instance of other diseases as well before treatment with this medicine is initiated.

Other medicines

This medicine is known to interact with a large number of medications you might possibly be taking. It is recommended to report the use of all medicines including herbs and supplements to the doctor to ensure safe and effective use.

Change in blood pressure

Use of large dose of this medicine can alter the levels of electrolytes like sodium and potassium in the body and may cause unexpected changes in blood pressure levels.

Withdrawal symptoms

Use of this medicine should not be abruptly stopped as the patient is likely to suffer from withdrawal symptoms. The use should be slowly and gradually withdrawn.

Growth disorders in children

This medicine should be used with caution in pediatric patients as the risk of growth abnormalities, brittle bones, and other developmental problems are significantly high.

Immunization procedures

Immunization procedures involving the injection of a live and weakened pathogen should be avoided while taking this medicine. Alternate means of immunization not involving a live strain of a microorganism could be considered.

Delayed wound healing

Use of this medicine can delay the process of wound healing.

Tuberculosis relapse

Use of this medicine can cause a relapse of tuberculosis in patients who have recently recovered from it. It is advised to conduct suitable diagnostic tests before starting the treatment with this medicine.

Defect in vision

Use of this medicine has been sometimes associated with an increase in intraocular pressure and may cause glaucoma or formation of cataract. It should be very carefully administered in patients who have a disease of the eye.

Epidural injections

Use of this medicine in an injectable form given in the lumbar region of the spinal chord has been associated with some major side effects and even fatalities. This route of administration for corticosteroids, in general, should be avoided.

Missed Dose

Contact your doctor for instructions if you missed a scheduled dose of this medicine. A self-attempt to make up for the lost dose may result in adverse effects.

Overdose

Contact your doctor if an overdose with this medicine for is suspected especially when the prescribed dose is very high. Symptoms may include thinning of the skin, easy bruising and bleeding, body fat deposits etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amlodipine

Mifepristone

Warfarin

Ethinyl Estradiol

Insulin

Ciprofloxacin

BCG vaccine

Disease interactions

Tuberculosis

This medicine should be used with caution in patients who have recently recovered from tuberculosis. The risks of a relapse are significantly high and hence close monitoring of signs and symptoms is necessary.

Electrolyte imbalance

This medicine is known to cause imbalances in the levels of minerals like calcium, potassium, and sodium in the body. Hence it should be administered with caution in patients with a pre-existing electrolyte imbalance disorder.

Gastrointestinal perforations

This medicine is known to cause perforations and bleeding in the gut especially when high doses are consumed. Hence this medicine should be administered with caution in patients having a pre-existing perforation disorder of the stomach or intestine.

Infections

This medicine can suppress the immune system especially if the dose is high. This may increase the chances of contracting an infection or reduce the capacity to fight an infection. Hence, this medicine or corticosteroids, in general, should not be used in patients with active infections.

Myocardial infarction

This medicine should be used with extreme caution in patients who have recovered or are recovering from a recent heart attack.

Ocular herpes infection

This medicine should be used with caution if the patient is suffering from an eye infection caused by herpes simplex virus.

Scleroderma

This medicine should be used with caution in patients suffering from this disease where the skin and connective tissue beneath becomes hard and stiff.

Threadworm infection

This medicine should be used with caution in patients suffering from an infection caused by threadworm (Strongyloides).
Food interactions
Information not available.
Lab interactions
Information not available.
Take Betamethasone as instructed by the doctor. Your dosage timings, forms, duration and other attributes are subject to vary depending on the condition and hence adherence to the instruction is necessary to ensure safe and effective use of this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by decreasing the release of certain substances that cause swelling of the internal organs as well as external swelling and irritation. It also works by suppressing or partially preventing the effect of the immune system.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Glucocorticoids

Schedule

Schedule H

[Internet]. 2017 [cited 27 April 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/29224

Betamethasone | C22H29FO5 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 27 April 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/9782

DailyMed - Betamethasone dipropionate cream BETAMETHASONE DIPROPIONATE- betamethasone dipropionate ointment BETAMETHASONE DIPROPIONATE- betamethasone dipropionate lotion [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 27 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=97dde5f5-a865-4af2-b562-8da72c8475f3

Betamethasone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 November 2017]. Available from:

https://www.drugbank.ca/drugs/DB00443

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 16 Nov 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.