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Benitowa beta 25 Tablet
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Benitowa beta 25 Tablet

Manufactured byAKUMENTIS HEALTHCARE LTD
ContainsBenidipine (4 mg) + Metoprolol (25 mg)
Description
Benitowa beta 25 Tablet is a medicine that consists of Benidipine and Metoprolol. It is used in the treatment of hypertension (high blood pressure) and angina pectoris (chest pain or chest discomfort). Benitowa beta 25 Tablet helps to lower your blood pressure, thereby reducing the chances of future heart attack and stroke. This medicine is not recommended for use in children below 18 years of age. Benitowa beta 25 Tablet can cause some common side effects like headache, swelling (anywhere on your body), flushing (sense of warmth in the face, ears, neck and trunk), slow heart rate, tiredness, nausea, stomach pain, constipation and a feeling of coldness in the fingers and toes. Consult your doctor if these side effects become severe. Do not take this medicine if you are allergic to it. Benitowa beta 25 Tablet can make you feel dizzy when you stand up suddenly, so it is advised that you get up slowly from a sitting or lying position. Avoid driving vehicles or operating machines as this medicine can cause drowsiness and can affect your concentration. Benitowa beta 25 Tablet can be taken with or without food. Take this medicine at the same time every day to maintain regular blood pressure levels. Avoid potassium-rich foods like bananas while taking this medicine. Do not stop taking this medicine without consulting your doctor as abruptly stopping the use of this medicine may lead to more serious conditions like a stroke or a heart attack. Benitowa beta 25 Tablet may not be suitable for all people. Inform your doctor if you have asthma or any other breathing conditions, kidney or liver problems. Consult your doctor before taking this medicine if you are pregnant, planning a pregnancy, or are breastfeeding. Your doctor may suggest tests for monitoring your electrolyte levels, blood sugar levels and kidney function to ensure this medicine is safe and effective for you.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Benitowa beta 25 Tablet

  • Headache
  • Dizziness
  • Constipation
  • Skin Rash
  • Nausea or vomiting
  • Lightheadedness
  • Palpitations
  • Oedema (accumulation of water in the tissues)
  • Difficulty in breathing
  • Low blood pressure
  • Slow heart beat
  • Excessive tiredness
  • Weight gain

Uses of Benitowa beta 25 Tablet

What is it prescribed for?

  • Hypertension
  • Angina pectoris
  • Acute heart attack
  • Ischemic heart disease
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effects of Benitowa beta 25 Tablet can be observed within 1 hour after taking it.
  • How long do the effects of this medicine last?
    This effects of Benitowa beta 25 Tablet may last for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid drinking alcohol while you are on treatment with Benitowa beta 25 Tablet because it can further lower the blood pressure and also increase the risk of symptoms like dizziness and loss of consciousness.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Benitowa beta 25 Tablet.
  • Can this medicine be taken during pregnancy?
    Use of Benitowa beta 25 Tablet should be avoided during pregnancy, as it may harm your foetus. Take this medicine only if prescribed by your doctor. Do not take or stop this medicine without consulting your doctor.
  • Can this medicine be taken while breast-feeding?
    Benitowa beta 25 Tablet is not recommended for use in breastfeeding women as it can be passed into breast milk in small amounts which may harm your baby. Do not start or stop taking this medicine without consulting your doctor.

Allergy

Avoid taking Benitowa beta 25 Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.

Severe bradycardia

Bradycardia or slow heart rate occurs when your heart beats less than 60 times per minute. It can lead to serious heart conditions like a heart attack in some people. Benitowa beta 25 Tablet is not recommended for use if you have bradycardia (a slow type of heartbeat). This medicine can affect the electrical impulses that regulate the heart functioning resulting in excessively lower blood pressure.

Second or third degree heart block

There are electrical signals that control the heartbeat and cause your heart muscle to contract and pump blood properly. Heart block occurs when these signals are slowed down. Heart blocks can be first, second, or third-degree. First-degree heart block is the least severe, second-degree heart block is severe and can often progress to third-degree heart block, the most severe form. Benitowa beta 25 Tablet should be avoided for use if you have a heart block in your heart greater than first degree due to the weakening of heart contractions and slowing of heart rate.
Warnings for special population

Pregnancy

Use of Benitowa beta 25 Tablet should be avoided during pregnancy, as it may harm your foetus. Take this medicine only if prescribed by your doctor. Do not take or stop this medicine without consulting your doctor.

Breast-feeding

Benitowa beta 25 Tablet is not recommended for use in breastfeeding women as it can be passed into breast milk in small amounts which may harm your baby. Do not start or stop taking this medicine without consulting your doctor.
General warnings

Driving or operating machines

Using Benitowa beta 25 Tablet may cause symptoms such as blurred vision, lightheadedness and dizziness. It is advised that you do not perform activities such as driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.

Use in children

Benitowa beta 25 Tablet is not recommended for use in children below 18 years of age as the safety and efficacy data is not available.

Use in elderly

Benitowa beta 25 Tablet should be used with caution in old people due to the increased risk of very low blood pressure. Your blood pressure needs to be monitored regularly while using this medicine. Your doctor will start the treatment at low doses and increase the dose based on your response to this medicine.

Major surgery

Inform your doctor you are planning to undergo major surgery before you start therapy with Benitowa beta 25 Tablet. Its blood pressure-lowering effect may affect the outcome of the surgery.

Liver disease

Benitowa beta 25 Tablet should be used with caution if you have liver problems due to the increased risk of severe side effects. This medicine breaks down and is absorbed in the liver. If you take this medicine when you have pre-existing liver problems, it may worsen your condition further.

Lung diseases

Benitowa beta 25 Tablet is not recommended for use if you have respiratory problems such as bronchial asthma, bronchospasm, or chronic obstructive pulmonary disease as it may worsen your condition. Your doctor may advise a suitable alternative based on your condition.

Peripheral vascular diseases

Use Benitowa beta 25 Tablet with caution if you have peripheral vascular conditions (blood vessel disorders) as it may worsen your condition. Report any unusual symptoms to the doctor immediately. Your doctor may advise a suitable alternative based on your condition.

Aortic stenosis

Aortic stenosis is the narrowing of the valve in the large blood vessel branching off the heart (aorta). Use Benitowa beta 25 Tablet with extreme caution if you have aortic stenosis due to the increased risk of very low blood pressure. Your doctor may monitor your heart function during the treatment. Your doctor may adjust the dose of this medicine or advise a suitable alternative based on your condition.

Missed Dose

If you forget to take a dose of Benitowa beta 25 Tablet, take it as soon as you remember. If it is time for your next dose, skip the missed dose and take your next dose at a scheduled time. Do not double your dose to compensate for a missed one.

Overdose

Never take more than the prescribed dose. If you suspect that you might have taken an overdose of Benitowa beta 25 Tablet, inform your doctor and seek immediate medical help.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid drinking alcohol while you are on treatment with Benitowa beta 25 Tablet because it can further lower the blood pressure and also increase the risk of symptoms like dizziness and loss of consciousness.
Interaction with Medicine

Antihypertensives

Ergotamine

Itraconazole

Aminophylline

Cimetidine

Diltiazem

Disease interactions

Severe hypotension or cardiogenic shock

Benitowa beta 25 Tablet is not recommended for use if you have low blood pressure or cardiogenic shock (a life-threatening condition where your heart abruptly stops pumping blood). Using this medicine will further decrease your heart’s ability to pump blood and reduce your blood pressure and heart rate drastically.

Liver disease

Benitowa beta 25 Tablet should be used with extreme caution if you have pre-existing or history of liver problems. This medicine breaks down in your liver and is excreted through urine. Using this medicine in such conditions may cause damage to your liver. Inform your doctor if you have liver troubles before taking this medicine. Your doctor may adjust the dose of this medicine and also, suggest tests to monitor your liver functioning while you are on treatment with this medicine.

Coronary artery disease

Benitowa beta 25 Tablet should be used with extreme caution if you have coronary artery diseases (a condition where the blood vessels of your heart are damaged). This medicine may weaken the contractions of your heart and slow down the heart rate which may worsen your condition and lead to other serious consequences. Your doctor may adjust the dose of this medicine or suggest some alternative based on your condition.

Chronic obstructive pulmonary disease (COPD)

Benitowa beta 25 Tablet should be used with caution if you have a respiratory condition such as asthma or chronic obstructive pulmonary disease (COPD). This medicine can cause shortness of breath and also worsen other symptoms of such respiratory conditions. Your doctor may adjust the dose of this medicine or suggest some alternative based on your condition.

Diabetes

Diabetes is a condition in which your blood sugar levels are high. Benitowa beta 25 Tablet can mask the symptoms of low blood sugar in people with diabetes. Your doctor may monitor your blood sugar levels if you are a diabetic and taking this medicine.

Glaucoma

Glaucoma is a group of eye conditions that damage the optic nerve due to increased intraocular pressure (high pressure inside the eyeball). This can lead to blindness. Benitowa beta 25 Tablet helps to lower this intra-ocular pressure. However, it should be used with caution if you have glaucoma as it may severely lower intraocular pressure leading to serious side effects. Your doctor will adjust the dose for its safe use.

Hyperlipidaemia

Benitowa beta 25 Tablet should be used with caution if you have hyperlipidemia (high blood cholesterol levels) due to the increased risk of worsening your condition. Your doctor may closely monitor your cholesterol levels, advise an appropriate dose of this medicine, or replace it with a suitable alternative based on your clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Benitowa beta 25 Tablet as it can increase the absorption of this medicine. This could lead to excessive lowering of blood pressure or worsen side effects.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Benitowa beta 25 Tablet as advised by your doctor. It can be taken with or without food. Do not take more or fewer doses than prescribed. Consult your doctor if you experience any undesirable effects or if you experience headaches after the first week of treatment. Do not stop the use of this medicine without consulting your doctor. Do not take any potassium-rich foods like bananas while using Benitowa beta 25 Tablet. Keep away from the reach of children and pets. Ensure that the unused medicine is disposed of properly.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Benidipine works by relaxing the heart muscles and blood vessels. Metoprolol blocks certain substances (catecholamines) which increases blood pressure. Together these medicines relax the blood vessels and reduce the heart rate, promote a smooth flowing of the blood. This causes lowering of your blood pressure to normal levels.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Calcium channel blocking agents, Cardioselective beta blockers, Antihypertensive combinations

Schedule

Schedule H

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https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=011ee828-5c2a-49b9-bf8e-07f5eb5fc635>

Drugs, H., 2021. Metoprolol: Medlineplus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 13 September 2021].

https://medlineplus.gov/druginfo/meds/a682864.html>

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Drugs.ncats.io. 2021. NCATS Inxight: Drugs — BENIDIPINE HYDROCHLORIDE. [online] Available at: < [Accessed 23 September 2021].

https://drugs.ncats.io/drug/0A6746FWDL>

Ohara-ch.co.jp. 2021. [online] Available at: < [Accessed 23 September 2021].

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2021. benidipine | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY. [online] Available at: <https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=10159> [Accessed 23 September 2021].

https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=10159Guidetopharmacology.org.

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Information on this page was last updated on 6 Oct 2021

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