Benidipine

Description

Benidipine is a calcium channel blocker. It relaxes the blood vessels and is used for the management of high blood pressure levels (hypertension) and angina pectoris (a type of chest pain that may be caused due to coronary artery disease). This medicine is not recommended for use in patients less than 18 years of age.

Side effects

Major & minor side effects for Benidipine

  • Headache
  • Dizziness
  • Constipation
  • Skin rash
  • Decreased blood pressure
  • Nausea
  • Lightheadedness
  • Palpitations
  • Edema

Uses of Benidipine

What is it prescribed for?

  • Hypertension
  • Angina pectoris
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required by this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to benidipine or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Liver impairment

This medicine should be used with caution in patients with a known history of liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Driving or Operating machinery

Use of this medicine may cause symptoms such as blurred vision, lightheadedness, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in Elderly

This medicine should be used with caution in elderly patients due to the increased risk of very low blood pressure levels. Regular monitoring of blood pressure levels is necessary while using this medicine. Therapy should be initiated at low doses and the dose may be increased based on the clinical condition and therapeutic response.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Antihypertensives

Itraconazole

Cimetidine

Rifampicin

Disease interactions

Hypotension

This medicine is not recommended for use in patients suffering from low blood pressure levels (hypotension) since it may further lower the blood pressure, causing severe adverse effects. Replacement with a suitable alternative should be considered based on the clinical condition.

Liver impairment

This medicine should be used with extreme caution in patients with liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function tests is required while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during therapy with this medicine due to the increased risk of severe side effects. Symptoms like dizziness, headache, swelling of the hands and feet, etc. may be experienced if grapefruit juice is consumed during treatment with this medicine.
Lab interactions
Information not available.
Take this medicine with food. Do not take it in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine relaxes the blood vessels. This ultimately reduces the blood pressure and improves chest pain.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Calcium channel blocking agents

Schedule

Schedule H

Benidipine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 7 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB09231

[Internet]. Ohara-ch.co.jp. 2018 [cited 7 September 2018]. Available from:

https://www.ohara-ch.co.jp/appendix/pdf/inc03/benidipineHydrochloride8T-SIE.pdf

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Information on this page was last updated on 1 Feb 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.