Balsalazide

Description

Balsalazide is a prodrug that is used in the treatment of ulcerative colitis. This medicine should be used with caution in children since the safety and efficacy of use are varied based on the dosage form of this medicine.

Side effects

Major & minor side effects for Balsalazide

  • Bloody diarrhea
  • Skin Rash
  • Fever
  • Lower back or side pain
  • Difficult or painful urination
  • Bladder pain
  • Chest tightness
  • Shortness of breath
  • Difficulty in breathing

Uses of Balsalazide

What is it prescribed for?

  • Ulcerative Colitis
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 10 days to 2 weeks of administration of the dose.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. The tablet form of this medicine is not recommended for use in females.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. The tablet form of this medicine is not recommended for use in females.

Allergy

This medicine is not recommended for use in patients with a known allergy to balsalazide, mesalamine, or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. The tablet form of this medicine is not recommended for use in females.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. The tablet form of this medicine is not recommended for use in females.
General warnings

Kidney function impairment

This medicine should be used with caution in patients with a known history of an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Liver impairment

This medicine should be used with caution in patients with a known history of an impaired liver function due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Asthma

This medicine should be used with caution in patients with asthma due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Coagulation disorders

This medicine should be used with caution in patients with coagulation disorders due to the increased risk of severe adverse effects such as excessive bleeding. Regular monitoring of prothrombin time and INR is necessary for such patients while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Pyloric stenosis

This medicine should be used with caution in patients with pyloric stenosis due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Use in Children

The tablet form of this medicine is not recommended for use in patients less than 18 years of age and the capsule form of this medicine is not recommended for use in patients less than 5 years of age since the safety and efficacy of use are not clinically established.

Acute intolerance syndrome

This medicine should be used with caution and the patient should be monitored frequently during therapy due to the increased risk of intolerance syndrome. Report any unusual symptoms to the doctor promptly. Therapy may need to be discontinued if an acute intolerance syndrome is suspected.

Use in Females

The tablet form of this medicine is not recommended for use in female patients since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Adefovir

Amikacin

Botulism immune globulin

Chloramphenicol

Tacrolimus

Cefaclor

Aspirin

Disease interactions

Renal Dysfunction

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food, as directed by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine blocks the actions of substances that are responsible for causing inflammation (swelling, redness, warmth, etc).
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

5-aminosalicylates

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 11 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/020610s017lbl.pdf

[Internet]. Accessdata.fda.gov. 2018 [cited 11 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022205s000lbl.pdf

Balsalazide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 11 September 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a699052.html

Colazide 750mg Capsules - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 11 September 2018]. Available from:

https://www.medicines.org.uk/emc/product/6391#

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 30 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.