Aztreonam

Description

Aztreonam is an antibiotic used to treat a variety of conditions such as urinary tract infections, lower respiratory tract infections, skin and skin structure infections, intraabdominal infections, etc. caused by bacteria. This medicine is not recommended for use in case of a common cold, flu, or other viral infections since it is active against infections caused by certain bacterial species only.

Side effects

Major & minor side effects for Aztreonam

  • Chest discomfort
  • Cough
  • Fever
  • Difficulty in breathing
  • Shortness of breath
  • Abdominal pain
  • Vomiting
  • Sore throat
  • Rash

Uses of Aztreonam

What is it prescribed for?

  • Urinary Tract Infection
  • Gynecological infections
  • Intraabdominal Infection
  • Skin and Skin Structure Infection
  • Lower Respiratory Tract Infection
  • Bacterial infections
Read More
Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed within 1 hour of an intravenous or intramuscular push and 1.5 hours of intravenous infusion.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to aztreonam or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Clostridium difficile-associated Diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.

Renal impairment

This medicine should be used with caution in patients with a known history of an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Drug resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Toxic Epidermal Necrolysis (TEN)

This medicine has rarely been known to cause toxic epidermal necrolysis, a potentially life-threatening skin disorder. Report any unusual symptoms to the doctor immediately. Close monitoring of clinical condition, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Missed Dose

Since this medicine is administered by a qualified healthcare professional in the clinic or hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinic setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Live cholera vaccine

Dicumarol

Anisindione

Ethinyl Estradiol

Warfarin

Entecavir

Disease interactions

Renal Dysfunction

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Gastrointestinal Diseases

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should be administered only by a qualified healthcare professional. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesired side effects to the doctor immediately.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by interfering with certain processes that help the bacteria to grow and increase in number.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Miscellaneous antibiotics

Schedule

Schedule H

Aztreonam - DrugBank [Internet]. Drugbank.ca. 2018 [cited 11 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00355

[Internet]. Packageinserts.bms.com. 2018 [cited 11 September 2018]. Available from:

https://packageinserts.bms.com/pi/pi_azactam.pdf

Azactam 1g Powder for Solution for Injection or Infusion, vial - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 11 September 2018]. Available from:

https://www.medicines.org.uk/emc/product/3773/smpc#

Aztreonam Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 11 September 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a687010.html

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 29 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.