Aztreonam

Description

Aztreonam is an antibiotic used to treat bacterial infections of the lungs, skin, bones, joints, stomach, and intestine. Aztreonam may also be used before, during, and after surgery to prevent infection. Aztreonam works by killing bacteria. It is not effective against infections caused by viruses or fungi. Aztreonam shows side effects like redness, irritation, or swelling at the injection site, diarrhoea, stomach pain, headache,nausea, and vomiting. Contact your doctor if these side effects become severe or persist for a longer duration. Aztreonam is given directly into a muscle or into a vein. Your doctor will determine how many doses you would need each day and how often the injections should be given based on the severity and location of the infection. Once an antibiotic is started, it is always recommended to finish the entire course of treatment. Aztreonam is not recommended for use if you are allergic to it. Inform your doctor if you have liver, kidney or heart problems and also about your ongoing medicines before receiving this injection. Also, inform your doctor if you are pregnant or are breastfeeding before using this medicine.

Side effects

Major & minor side effects for Aztreonam

  • Chest discomfort
  • Cough
  • Fever
  • Difficulty in breathing
  • Shortness of breath
  • Abdominal pain
  • Vomiting
  • Sore throat
  • Rash

Uses of Aztreonam

What is it prescribed for?

  • Urinary Tract Infection
  • Gynecological infections
  • Serious abdominal infection
  • Bacterial skin infections
  • Lower Respiratory Tract Infection
  • Bone and Joint infections
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of Aztreonam can be observed within 1 hour.
  • Duration of effect
    The amount of time for which Aztreonam remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported for Aztreonam
  • Usage in pregnancy?
    Aztreonam is not recommended for use during pregnancy as it may cause harm to your foetus. Consult your doctor if you are pregnant.
  • Usage while breast-feeding?
    Aztreonam is not recommended for use if you are breastfeeding as this medicine may pass in your breast milk. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Aztreonam if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Aztreonam is not recommended for use during pregnancy as it may cause harm to your foetus. Consult your doctor if you are pregnant.

Breast-feeding

Aztreonam is not recommended for use if you are breastfeeding as this medicine may pass in your breast milk. Hence, consult your doctor if you are breastfeeding.
General warnings

Diarrhoea

Aztreonam can kill the helpful bacteria in your stomach or intestine and lead to diarrhoea. Use this medicine with extreme caution if you have stomach and intestinal problems, particularly colitis (swelling of the inner lining of the colon), as it may worsen your condition.

Liver Disease

Aztreonam should be used with caution if you have liver problems. This medicine may further increase the risk of increased liver enzymes and liver damage. Inform your doctor of any history of jaundice (a condition that causes your skin and whites of the eyes to turn yellow) or other liver conditions you may have so he/she may prescribe an alternate medicine or recommend dose adjustments.

Antibiotic resistance

Antibiotic resistance occurs when the bacteria no longer respond to the antibiotics intended to kill them. Complete your entire course of treatment with Aztreonam, even if your condition gets better to avoid antibiotic resistance.

Toxic Epidermal Necrolysis (TEN)

Aztreonam has rarely been known to cause toxic epidermal necrolysis, a potentially life-threatening skin disorder. Report any unusual symptoms to the doctor immediately.

Missed Dose

Since Aztreonam is administered by a qualified healthcare professional in the clinic or hospital setting, the likelihood of a missed dose is very low.

Overdose

Since Aztreonam is administered in the hospital or clinic setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Live cholera vaccine

Dicumarol

Anisindione

Ethinyl Estradiol

Warfarin

Entecavir

Disease interactions

Kidney dysfunction

Aztreonam is excreted via the kidney and may get accumulated in your body if your kidneys are not functioning properly. This can increase the risk of severe side effects. Hence, this medicine should be used with caution if you have severe kidney problems.

Gastrointestinal Diseases

Aztreonam should be used with caution if you have gastrointestinal disorders, particularly colitis (swelling of the large intestine), as it can worsen your condition. Inform your doctor if you experience symptoms like diarrhoea, abdominal pain, blood in stools, etc.
Food interactions
Information not available.
Lab interactions
Information not available.
Aztreonam should be administered only by a qualified healthcare professional. Inform the doctor if you have an allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Avoid discontinuation of this medicine without consulting your doctor as it may lead to a relapse of your condition.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Aztreonam works by killing bacteria.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Miscellaneous antibiotics

Schedule

Schedule H

Please also see full prescribing information for azactam ... - BMS (no date). Available at: (Accessed: December 1, 2022).

https://packageinserts.bms.com/pi/pi_azactam.pdf

Aztreonam injection: Medlineplus Drug Information (no date) MedlinePlus. U.S. National Library of Medicine. Available at: (Accessed: December 1, 2022).

https://medlineplus.gov/druginfo/meds/a687010.html

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Information on this page was last updated on 5 Jan 2023

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.