Azilsartan

Description

Azilsartan is used in the treatment of high blood pressure. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect. This medicine is not recommended for use in patients less than 18 years of age.

Side effects

Major & minor side effects for Azilsartan

  • Diarrhea
  • Dizziness
  • Nausea
  • Fatigue
  • Cough
  • Sweating
  • Blurred vision
  • Muscle spasm

Uses of Azilsartan

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 2 hours of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, fainting, changes in heart rate, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to azilsartan or any other inactive ingredients present along with this medicine.

Aliskiren

Coadministration of aliskiren and this medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients suffering from diabetes and kidney diseases.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Hyperkalemia

This medicine may increase the potassium levels in the blood (hyperkalemia) in some patients. This may cause serious side effects such as fatal cardiac rhythm irregularities, kidney function impairment, muscle paralysis, etc. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine. Close monitoring of blood potassium levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Hypotension

Symptomatic hypotension may occur in patients with volume depletion or patients who are treated with high-dose diuretics during treatment with this medicine. Hence, it is advised to correct volume depletion and/or adjust the doses of patient's medicines before initiating treatment with Azilsartan.

Renal impairment

This medicine should be used with caution in patients with a known history of kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of renal function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Pediatric population

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, fainting, changes in heart rate, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Aliskiren

Captopril

Insulin

Trimethoprim

Disease interactions

Angioedema

This medicine should be used with caution in patients with a known history of angioedema due to the increased risk of worsening of the patient's condition. Report any symptoms such as swelling of the face or lips, difficulty swallowing, difficulty breathing, etc. to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Congestive heart failure

This medicine should be used with extreme caution in patients suffering from congestive heart failure due to the increased risk of worsening of the patient's condition. Close monitoring of heart function, blood pressure, and kidney function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food. Do not take in larger or smaller amounts than prescribed. Report any unusual symptoms to the doctor immediately. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine promotes a smooth flow of blood by blocking the action of certain natural substances that cause blood vessel narrowing.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Angiotensin receptor blockers

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 24 July 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/200796s000lbl.pdf

Azilsartan medoxomil - DrugBank [Internet]. Drugbank.ca. 2018 [cited 24 July 2018]. Available from:

https://www.drugbank.ca/drugs/DB08822

Azilsartan: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 24 July 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a611028.html

DailyMed - Azilsartan kamedoxomil tablet [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 24 July 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=52b27c75-9f5a-4816-bafd-dace9d7d2063

Edarbi Tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 24 July 2018]. Available from:

https://www.medicines.org.uk/emc/product/4074

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Information on this page was last updated on 26 Jul 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.