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AxanT Tablet

Manufactured bySigmund Promedica
ContainsMetaxalone (400 mg) + Diclofenac (50 mg)
Description
AxanT Tablet is a combination of Metaxalone and Diclofenac. It is used to reduce pain occurring due to muscle spasms (contractions). AxanT Tablet stops the release of certain chemical messengers responsible for pain and muscle stiffness. Your doctor may advise physical therapy and rest, along with this medicine to obtain the best possible effect. AxanT Tablet relieves pain and swelling due to musculoskeletal conditions but does not cure them. Common side effects of AxanT Tablet includes drowsiness, dizziness, nausea, vomiting, stomach pain, stomach upset, loss of appetite and diarrhoea. Contact your doctor if any side effects are seen for a longer period of time. Avoid driving or operating a machine as this medicine can cause drowsiness. Take AxanT Tablet with food to avoid stomach. Take this medicine daily as advised by the doctor. For the ease of remembering, take it at around the same time every day. Use AxanT Tablet with caution if you have a history of liver or kidney problems. Avoid using this medicine if you are previously allergic to it. AxanT Tablet is not recommended in children below 12 years of age and in pregnant women due to serious side effects to the foetus.

Side effects

Major & minor side effects for AxanT Tablet

  • Constipation
  • Skin rash
  • Ringing or buzzing in the ears
  • Dizziness and Drowsiness
  • Stomach pain
  • Nausea and Vomiting
  • Diarrhoea
  • Headache
  • Nervousness
  • Chest pain
  • Loss of appetite
  • Shortness of breath
  • Black or tarry stools
  • Difficult or painful urination
  • Itching
  • Cough
  • Stomach upset
  • Heart burn

Uses of AxanT Tablet

What is it prescribed for?

  • Acute musculoskeletal pain
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The pain-relieving effect of AxanT Tablet can be observed within 30 minutes of taking the tablet orally.
  • How long do the effects of this medicine last?
    AxanT Tablet may remains active in the body for up to 8 hours. You may have to take the next dose if your symptoms continue.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol with AxanT Tablet may increase the side effects such as dizziness, headache, gastrointestinal bleeding, weakness, fatigue, etc.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported. for AxanT Tablet.
  • Can this medicine be taken during pregnancy?
    Avoid AxanT Tablet during pregnancy due to the risk of serious side effects to the foetus. Your doctor may advise an alternative medicine for the treatment.
  • Can this medicine be taken while breast-feeding?
    AxanT Tablet is not known whether it passes in the breast milk. However, it should only be used upon your doctor's recommendation.

Allergy

Avoid taking AxanT Tablet if you are allergic to it. If you notice any symptoms such as skin rash, itching/swelling, dizziness, breathing difficulties, etc. seek an immediate medical attention.

Active peptic ulcer

Peptic ulcers are the sores (blisters) that are formed in the linings of the stomach and intestine. Avoid the use of AxanT Tablet if you have an active peptic ulcer or are suspected of having it. AxanT Tablet is known to damage the mucosal lining in the stomach and intestine. Thus, it could cause severe swelling and bleeding and worsen the disease condition.

Drug-induced hemolytic anemia

Hemolytic anemia is a condition in which the red blood cells are destroyed rapidly. Drug-induced hemolytic anemia may occurs when a medicine triggers the body's defense system to attack its own red blood cells. AxanT Tablet is not recommended for use in patients suffering from drug-induced hemolytic anaemia or other anemias due to the increased risk of worsening of the patient's condition.

Coronary Artery Bypass Surgery (CABG)

Coronary bypass surgery is a procedure in to restores normal blood flow to your heart muscle by diverting the flow of blood around the blocked artery. AxanT Tablet is not recommended for relieving pain after heart surgery as it increases the risk of heart attack or stroke.
Warnings for special population

Pregnancy

Avoid AxanT Tablet during pregnancy due to the risk of serious side effects to the foetus. Your doctor may advise an alternative medicine for the treatment.

Breast-feeding

AxanT Tablet is not known whether it passes in the breast milk. However, it should only be used upon your doctor's recommendation.
General warnings

Effect on heart

Prolonged use of AxanT Tablet may cause serious adverse effects in patients with heart diseases. Close monitoring of heart function and vital signs may be required.

Gastro-intestinal toxicity

Long term use of AxanT Tablet can cause damage to the stomach and intestine. Serious conditions like bleeding, ulceration and perforation (holes) in the lining of the stomach or intestinal wall may occur.

Use in elderly

AxanT Tablet should be used with caution in elderly patients (above 65 years of age) due to the increased risk of serious side effects.

Use in children

Safety and efficacy of AxanT Tablet have not been clinically established in children under the age of 12 years.

Sedation

Use of AxanT Tablet may cause moderate to severe sedation. Hence, avoid driving vehicles and operate a machine after taking this medicine.

Fluid retention and oedema

Close monitoring of blood pressure, electrolyte levels, and heart function are necessary for patients taking AxanT Tablet as it may cause oedema (accumulation of body fluid under the skin) in some patients.

Skin allergies

AxanT Tablet may cause serious skin allergies without any warnings in rare cases. Signs and symptoms like rashes, hives, fever, or other allergic symptoms should be reported to your doctor immediately.

Kidney Impariment

AxanT Tablet should be used with caution in mild to moderate kidney impairment. In such conditions, increased accumulation of the medicine may lead to further kidney damage.

Missed Dose

In case the scheduled dose of AxanT Tablet is forgotten, take it as soon as you remember. If it is almost time for the next dose, skip the forgotten dose. Do not double the dose.

Overdose

Never take more than the prescribed dose of AxanT Tablet. In case you have taken an overdose of this medicine, seek an emergency medical department.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol with AxanT Tablet may increase the side effects such as dizziness, headache, gastrointestinal bleeding, weakness, fatigue, etc.
Interaction with Medicine

Amitriptyline

Methotrexate

Ramipril

Tramadol

Adefovir

Apixaban

Ketorolac

Disease interactions

Asthma

Use AxanT Tablet with caution in patients with preexisting asthma. Avoid the use of this medicine if the patient has a history of aspirin-sensitive asthma as this medicine may cause bronchospasm (narrowing of the airways in your lungs).

Impaired kidney function

Chronic use of AxanT Tablet may cause kidney toxicity as this medicine is eliminated by the kidney. Hence, close monitoring of kidney function is necessary.

Heart Disease

AxanT Tablet is known to increase the risk of heart attack and stroke in patients with heart diseases. Therefore, caution should be maintained.

Anemia

Do not use AxanT Tablet in patients with drug-induced hemolytic anaemia or other anaemias due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered based on the clinical condition.

Liver Disease

If you have liver disease, avoid taking AxanT Tablet. Overdose can produce more active forms and leads to liver damage.
Food interactions
Information not available.
Lab interactions
Information not available.
Take AxanT Tablet orally with food to avoid gastric irritation. Do not chew or crush the tablet in the mouth. Never take more than the prescribed dose. Take this medicine at around the same time daily. AxanT Tablet along with physical therapy and rest helps to relieve pain in conditions such as strains, sprains, and other muscle injuries. Avoid driving or consuming alcohol as it can make you drowsy.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
AxanT Tablet consists of Metaxalone and Diclofenac which helps to reduce pain and improves muscle movement. Metaxalone blocks the nerve signals (pain sensation) from reaching the brain. Diclofenac works by reducing the formation of certain substances in the body that are responsible for causing pain and inflammation (swelling).
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Skeletal muscle relaxants, Non-steroidal anti-inflammatory agent combinations

Schedule

Schedule H

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https://pubchem.ncbi.nlm.nih.gov/compound/Diclofenac>

Pubchem.ncbi.nlm.nih.gov. 2021. Metaxalone. [online] Available at: < [Accessed 16 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/metaxalone>

Drugs, H., 2021. Metaxalone: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 16 July 2021].

https://medlineplus.gov/druginfo/meds/a682010.html>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 4 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/13217s036lbl.pdf>

Dailymed.nlm.nih.gov. 2021. DailyMed - METAXALONE tablet. [online] Available at: < [Accessed 4 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=de3448df-4ca1-44ec-bad1-486549cddf64>

Medicines.org.uk. 2021. Diclofenac Potassium 50 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 4 August 2021].

https://www.medicines.org.uk/emc/product/4515/smpc#gref>
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Information on this page was last updated on 5 Aug 2021

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