Augmexx (500/100 mg) Injection
Manufactured byVhb Life Sciences Inc
ContainsAmoxycillin (500 mg) + Clavulanic Acid (100 mg)
Description
Augmexx (500/100 mg) Injection is a combination medicine used to treat a variety of bacterial infections. Amoxycillin interferes with the growth and division process of the bacterial cell wall while clavulanic acid ensures extended anti-bacterial activity. This combination is used to treat bacterial infections of the lungs and airways, middle ear, sinuses, skin, bone and joints, and the urinary tract.
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Substitutes
List of substitutes for Augmexx (500/100 mg) Injection
Side effects
Major & minor side effects for Augmexx (500/100 mg) Injection
- Allergic Skin Reaction
- Diarrhea
- Fever
- Joint pain
- Skin yellowing
- Easy bruising and bleeding
- Heavy menstrual bleeding
- Tooth discoloration
- Nausea or vomiting
- Altered sense of taste
- Convulsions
- Painful intercourse
- Swelling of face, lips, eyelids, tongue, hands and feet
- Black or tarry stools
- Muscle or joint pain
- Sleeplessness
- Irregular heartbeat
Uses of Augmexx (500/100 mg) Injection
What is it prescribed for?
- Ear Infection (Otitis Media)
- Nose Infection (Sinusitis)
- Throat Infection (Tonsillitis/Pharyngitis)
- Lower Respiratory Tract Infection
- Skin Infection
- Urinary Tract Infection
- Infections associated with surgical procedures
- Bone and joint infections
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Concerns
Commonly asked questions
- Onset of actionThe effect of this medicine can be observed within 1-2 hours of administration.
- Duration of effectThe effect of this medicine lasts for an average duration of 6-8 hours.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit forming tendencies were reported.
- Usage in pregnancy?This medicine should be used in pregnant women only if the need is clearly established and the benefits outweigh the risks. Consult your doctor before using this medicine.
- Usage while breast-feeding?This medicine should be used in breastfeeding women only if the need is clearly established. Consult your doctor before using this medicine.
Allergy
This medicine is not recommended for use if you have a known history of allergy to Amoxycillin or Clavulanic acid derivatives. Do not consume this medicine if you have a known history of allergy to Penicillins or Beta lactam antibiotics.
Cholestasis
This medicine is not recommended for use if you have had a condition where the normal flow of bile from the liver is interrupted (cholestasis).
Liver dysfunction
This medicine is not recommended for use if you have a history of liver dysfunction associated with the use of these medicines in combination.
Warnings for special population
Pregnancy
This medicine should be used in pregnant women only if the need is clearly established and the benefits outweigh the risks. Consult your doctor before using this medicine.
Breast-feeding
This medicine should be used in breastfeeding women only if the need is clearly established. Consult your doctor before using this medicine.
General warnings
Allergic Reaction
This medicine is likely to cause moderate to severe allergic reaction and the likelihood is very high in patients who are known to have an antibiotic allergy. Report the occurrence of any such reaction to the doctor on priority.
Diarrhea
Use of this medicine is likely to cause diarrhea. It may be a mild episode requiring no specific treatment or a severe case of colitis or Clostridium Difficile-Associated Diarrhea (CDAD). Chances of occurrence are very high in patients having a history of diarrhea after using antibiotics. All such instances should be reported to the doctor on priority.
Mononucleosis
This medicine is not recommended for use in patients with Mononucleosis. This medicine is likely to cause rashes and bumps on the skin if the patient is suffering from Mononucleosis.
Drug-resistance
Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.
Liver disease
This medicine should be used with caution in patients having an impairment of the normal liver function. It is advised to regularly monitor the liver enzyme levels while taking this medicine and even after treatment with this medicine is complete.
Form and method of administration
This medicine is generally administered either by slow intravenous injection over a period of 3-4 minutes or by intravenous infusion over a period of 30-40 minutes. It is not suitable for intramuscular administration. The patient should be shifted to oral forms as soon as possible.
Missed Dose
Since this medicine is administered in a clinical or a hospital setup, the likelihood of a missed dose is very low. Contact your doctor immediately if you have missed a scheduled dose of this medicine.
Overdose
Since this medicine is administered in a clinical or a hospital setup, the likelihood of an overdose is very low. However, if an overdose of this medicine is suspected, your doctor will initiate emergency medical treatment. Symptoms of an overdose may include nausea, vomiting, diarrhea, drowsiness, etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Doxycycline
Methotrexate
Warfarin
Ethinyl Estradiol
Live vaccines
Disease interactions
Mononucleosis
This medicine is not recommended for use in patients with a history of mononucleosis since these patients may develop a skin reaction/eruption. Replacement with a suitable alternative should be done under your doctor's supervision.
Colitis
This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis. Inform your doctor if you have any history of gastrointestinal diseases. Report any incidence of severe diarrhea, abdominal pain, and blood in stools to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition.
Renal Diseases
This medicine should be used with caution in patients with a history of renal diseases or active renal diseases. Close monitoring of the renal function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Urine Sugar Test (Benedict's of Fehling's reagent)
Report the use of this medicine prior to the test. This medicine may give a false positive result for the presence of glucose/sugar in the urine. The urine sugar test should be performed with a different reagent in case you are receiving this medicine.
Administer Augmexx (500/100 mg) Injection exactly as prescribed by the doctor. It is recommended to take this medicine under the supervision of a doctor or a trained healthcare professional.
Miscelleneous
How it works
Amoxycillin binds to certain specific receptors and prevents the formation of a necessary component for cell wall building process. Clavulanic acid is effective against a specific species of bacteria that are resistant to other antibiotic medicines. Thus, the combination becomes effective against an extended range of bacteria.
Legal Status
Classification
Category
Beta-lactamase inhibitors, Aminopenicillins
Schedule
Schedule H
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Amoxicillin and Clavulanic Acid: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 1 August 2017]. Available from:
DailyMed - AMOXICILLAN AND CLAVULANATE POTASSIUM- amoxicillan and clavulanate potassium tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 1 August 2017]. Available from:
Clavulanate - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 August 2017]. Available from:
Amoxicillin - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 August 2017]. Available from:
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