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Augmentin (400/57 mg) Syrup

Manufactured byGlaxosmithkline Pharmaceuticals Ltd.
ContainsAmoxycillin (400 mg) + Clavulanic Acid (57 mg)
Description
Augmentin (400/57 mg) Syrup is a combination of Amoxycillin and Clavulanic acid. Augmentin (400/57 mg) Syrup is used to treat many bacterial infections of the lungs and airways, middle ear, sinuses, skin, teeth, and urinary tract. It is also used to treat multidrug-resistant Tuberculosis. Amoxycillin interferes with the growth and division process of the bacterial cell wall while Clavulanic acid enhances the activity of Amoxycillin in treating caused by bacteria. This medicine is generally meant to be used in children. However, your doctor may prescribe this medicine to patients who cannot swallow the tablet or capsule. The common side effects of Augmentin (400/57 mg) Syrup are nausea, vomiting, stomach pain, and skin rash. Usually, these side effects are self-limiting. Consult the doctor at the earliest if any of these side effects persist or bothers your child. Before giving this medicine to your child, inform your doctor if your child is allergic to any antibiotics. You can give Augmentin (400/57 mg) Syrup to your child with food as it improves absorption and decreases the risks of stomach upset. Your child's doctor will decide the dose and frequency based on the severity of infection, body weight and age of your child. Stick to the dose, time, and way prescribed. Also, ensure to complete the course of treatment even if your child starts feeling better after taking few doses. To make sure Augmentin (400/57 mg) Syrup is safe, share your child’s entire medical history with the doctor, including any previous episode of allergy, heart problem, a blood disorder, birth defects, lung problem, stomach or intestinal problem, skin disorder, liver disease, or kidney disease. This information is critical as it can help your paediatrician in planning an overall treatment and dose adjustments for your child.

Side effects

Major & minor side effects for Augmentin (400/57 mg) Syrup

  • Allergic Skin Reaction
  • Diarrhoea
  • Fever
  • Skin yellowing
  • Easy bruising and bleeding
  • Tooth discoloration
  • Nausea or vomiting
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Black or tarry stools
  • Muscle or joint pain
  • Sleeplessness

Uses of Augmentin (400/57 mg) Syrup

What is it prescribed for?

  • Acute otitis media
  • Sinusitis
  • Lower respiratory tract infection
  • Skin infections
  • Pharyngitis/Tonsilitis
  • Urinary tract infection
  • Multidrug resistant Tuberculosis
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Augmentin (400/57 mg) Syrup starts working within 1-2 hours of administration.
  • How long do the effects of this medicine last?
    The effect of Augmentin (400/57 mg) Syrup lasts for an average duration of 6-8 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    Augmentin (400/57 mg) Syrup has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    Augmentin (400/57 mg) Syrup is only recommended to use in children.
  • Can this medicine be taken while breast-feeding?
    Augmentin (400/57 mg) Syrup is only recommended to use in children.

Allergy

Avoid administration of Augmentin (400/57 mg) Syrup if your child is previously allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Cholestasis

Augmentin (400/57 mg) Syrup should be avoided for use if your child has a condition where the normal flow of bile from the liver is interrupted (cholestasis).

Liver dysfunction

Avoid using Augmentin (400/57 mg) Syrup if your child has a history of liver disease associated with the use of this medicine or any other antibiotics.
Warnings for special population

Pregnancy

Augmentin (400/57 mg) Syrup is only recommended to use in children.

Breast-feeding

Augmentin (400/57 mg) Syrup is only recommended to use in children.
General warnings

Diarrhoea

Augmentin (400/57 mg) Syrup can cause diarrhoea because it may also kill the helpful bacteria in your child's stomach or intestine. Seek emergency medical help if your child gets diarrhoea by using this medicine.

Antibiotic resistance

Finish the entire course of treatment with Augmentin (400/57 mg) Syrup, even if your child's condition gets better to avoid antibiotic resistance (bacteria develops the ability to overcome the antibiotic's ability to kill them).

Liver disease

Regular monitoring of the liver enzyme levels is necessary while giving Augmentin (400/57 mg) Syrup to your child and even after completion of treatment with this medicine.

Form of medication

Augmentin (400/57 mg) Syrup is normally used in pediatric patients. However, adult patients who are unable to chew or swallow the solid form can use the liquid form under their doctor's supervision.

Missed Dose

If you forget to give a Augmentin (400/57 mg) Syrup dose to your child, make sure that you remember to give your next dose on time. Do not give two doses together to make up for a forgotten dose.

Overdose

Never give Augmentin (400/57 mg) Syrup more than the prescribed dose. If you suspect that you might have given an overdose of this medicine and observing difficulty in the child, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Doxycycline

Methotrexate

Warfarin

Live vaccines

Disease interactions

Colitis

Augmentin (400/57 mg) Syrup can kill the helpful bacteria in your child's stomach or intestine and leads to diarrhoea. Therefore use this medicine with extreme caution in children with colitis (swelling of the inner lining of the colon).

Kidney diseases

Children with kidney diseases need special consideration while taking Augmentin (400/57 mg) Syrup due to the risk of kidney damage. Dose adjustment should be done based on the clinical condition of your child.
Food interactions
Information not available.
Lab interactions
Information not available.
Give Augmentin (400/57 mg) Syrup to your child with food to decrease the stomach upset. Must complete the entire course of Augmentin (400/57 mg) Syrup as abrupt stopping may recur the infection, or cause another infection. Your child may have a bitter taste in the mouth after taking Augmentin (400/57 mg) Syrup. Eating citrus fruit or fruit juice may help. Encourage your child to drink plenty of water in case diarrhoea develops as a side effect. Never give Augmentin (400/57 mg) Syrup until and unless prescribed by the doctor. You must also never share your child’s medicine with anyone else even if they show similar symptoms. Avoid giving Augmentin (400/57 mg) Syrup to treat the common cold and flu-like symptoms caused by viruses. Never save Augmentin (400/57 mg) Syrup for future. It cannot be said whether the same medicine will work on future infections. Discard the medicine if the seal is broken or the appearance of the liquid changes. Stop Augmentin (400/57 mg) Syrup immediately if your child develops an itchy rash, facial swelling, or breathing difficulty. Report to the doctor without any delay.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Augmentin (400/57 mg) Syrup is a combination of Amoxycillin and Clavulanic acid. Amoxycillin binds to certain specific receptors and prevents the formation of a necessary component for the cell wall building process. Clavulanic acid is effective against a specific species of bacteria that are resistant to other antibiotic medicines.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Beta-lactamase inhibitors, Aminopenicillins

Schedule

Schedule H

Drugs, H., 2021. Amoxicillin and Clavulanic Acid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 20 May 2021].

https://medlineplus.gov/druginfo/meds/a685024.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - AMOXICILLAN AND CLAVULANATE POTASSIUM tablet, film coated. [online] Available at: < [Accessed 20 May 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=909c85de-c076-4444-b63c-cd8bdc556f36>

Ca.gsk.com. 2021. [online] Available at: < [Accessed 31 May 2021].

https://ca.gsk.com/media/590864/clavulin.pdf>

Pubchem.ncbi.nlm.nih.gov. 2021. Clavulanic acid. [online] Available at: < [Accessed 20 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Clavulanic-acid>

Pubchem.ncbi.nlm.nih.gov. 2021. Amoxicillin. [online] Available at: < [Accessed 22 January 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Amoxicillin>
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Information on this page was last updated on 13 Aug 2021

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.