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Atropine 0.5 mg Infusion
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Atropine 0.5 mg Infusion

Manufactured byDenis Chem Lab Ltd.
ContainsAtropine
Description
The primary ingredient of Atropine 0.5 mg Infusion is an anticholinergic medicine that produces many effects in the body. This medicine is used for the management of bradycardia (slow heart rate) caused by heart block or any other medical conditions. It is also used to decrease the production of saliva and other fluid secretions during surgery. It is effective to treat severe spasms or cramps in the stomach, intestines, and other organs of the body. It is also sometimes used as an antidote for poisoning by certain insecticides.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Atropine 0.5 mg Infusion

  • Dry mouth
  • Blurred vision
  • Dry eyes
  • Increased heartbeat
  • Loss of taste
  • Difficulty in breathing
  • Restlessness
  • Drowsiness

Uses of Atropine 0.5 mg Infusion

What is it prescribed for?

  • Bradyarrhythmia
  • Preoperative medication
  • Organophosphate Poisoning
  • Radiographic Examinaton
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is 4 hours.
  • Is it safe to consume alcohol while taking this medicine?
    It is recommended not to consume alcohol while receiving this medicine due to the increased risk of drowsiness and dizziness. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while using this medicine. Report any incidence of breathing difficulty or dizziness to the doctor immediately.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to atropine or any other inactive ingredient present along with the formulation.

Narrow angle glaucoma

This medicine is not recommended for use in patients who are suffering from narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Pyloric stenosis

This medicine is not recommended for use in patients with a known history of pyloric stenosis since it may worsen the condition.

Prostatic hypertrophy

This medicine is not recommended for use in patients with a known history of prostatic hypertrophy (enlarged prostate) since it may worsen the condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Heat intolerance

This medicine increases the risk of heat intolerance at high temperatures. Report to the doctor if you experience any undesired effects while receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Gastric ulcer

This medicine has been shown to worsen the condition of a gastric ulcer due to delayed gastric emptying. Discuss the risks and benefits with the doctor before receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Liver diseases

This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Kidney diseases

This medicine should be used with caution in patients with kidney diseases due to the increased risk of adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Tachycardia

This medicine should be used with caution in patients with a known history of tachycardia and unstable heart rate. The use of this medicine may increase the risk of a very high heart rate. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

It is recommended not to consume alcohol while receiving this medicine due to the increased risk of drowsiness and dizziness. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while using this medicine. Report any incidence of breathing difficulty or dizziness to the doctor immediately.
Interaction with Medicine

Amitriptyline

Clozapine

Metoclopramide

Topiramate

Ipratropium

Dicyclomine

Zonisamide

Disease interactions

Myasthenia Gravis

This medicine is not recommended for use in patients with a history of myasthenia gravis since it may interact with the medicines given for myasthenia gravis and cause worsening of the condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Ulcerative colitis

This medicine should be used with extreme caution in patients with a known history of ulcerative colitis due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Hypertension

This medicine should be used with caution in patients with a known history of hypertension due to the increased risk of very high blood pressure. Close monitoring of blood pressure is advised while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Coronary Artery Disease

This medicine should be used with caution in patients with known history heart diseases due to the increased risk of worsening of the patient's condition. Close monitoring of heart function may be required in patients with heart diseases. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine works by blocking the effects of a certain specific chemical (acetylcholine) in various parts of the body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Anticholinergics, Chronotropic agents, Antidotes, and Antispasmodics.

Schedule

Schedule H

Atropine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 21 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB00572

DailyMed - Atropine Sulfate - atropine sulfate injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 21 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5d45eb2f-b964-4f64-b277-eef807520466

Atropine Sulfate Injection 1mg in 1ml - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 28 April 2020]. Available from:

https://www.medicines.org.uk/emc/product/3587/smpc

[Internet]. Rad-ar.or.jp. 2020 [cited 28 April 2020]. Available from:

http://www.rad-ar.or.jp/siori/english/kekka.cgi?n=42938

Atropine Sulfate Injection 600mcg in 1 ml (ampoules) - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 9 July 2020]. Available from:

https://www.medicines.org.uk/emc/product/3695/smpc
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Information on this page was last updated on 9 Jul 2020

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