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Aten-D Tablet
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Aten-D Tablet

Manufactured byZydus Cadila
ContainsAtenolol (50 mg) + Indapamide (2.5 mg)
Description
Aten-D Tablet is a combination medicine which may be used to reduce hypertension (high blood pressure) as well as edema (swelling) and fluid retention caused by heart diseases. It may also be used for treating other complications associated with heart and blood vessels. Patients are advised to follow a strict exercise and diet regimen along with this medicine to get the best possible effect. It should be used with caution in patients with severe kidney diseases due to the increased risk of severe side effects. Frequent monitoring of blood pressure and electrolytes level is necessary while taking this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Aten-D Tablet

  • Blurred vision
  • Difficulty in breathing
  • Sweating
  • Cold hands or feet
  • Anxiety
  • Chest pain
  • Dizziness
  • Decrease in frequency of urination
  • Loss of appetite
  • Dry mouth
  • Itching or rash
  • Abdominal pain
  • Headache
  • Joint pain, stiffness, and swelling

Uses of Aten-D Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 12 to 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while receiving this medicine due to the increased risk of dizziness, fainting, and very low blood pressure. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to atenolol, indapamide, or any other inactive ingredients present in the formulation.

Heart diseases

This medicine is not recommended for use in patients with heart diseases such as a heart block, sinus bradycardia, heart failure, cardiogenic shock, or sinus syndrome since it may worsen the patient's condition.

Severe pulmonary edema

This medicine is not recommended for use in patients with severe pulmonary edema due to the increased risk of severe adverse effects.

Anuria

This medicine is not recommended for use in patients with anuria (a condition where the kidney is unable to produce urine) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Cardiac Failure

Use of this medicine may cause heart failure and reduced blood flow in patients having a heart disease. Close monitoring of heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Major surgery

This medicine should be used with caution in patients who are scheduled to undergo a major surgery. An anesthetic agent with little negative inotropic activity should be selected to minimize the effect on the heart.

Lung Diseases

This medicine should be used with caution in patients with lung diseases who do not respond to other antihypertensive medications. Start with the lowest possible dose and increase the dose based on the clinical condition. Replacement with a suitable alternative may be required in some cases.

Hyperlipidemia

This medicine should be used with caution in patients with hyperlipidemia since it may alter the serum lipid profiles. Appropriate dose adjustments or replacement with a suitable alternative should be considered under your doctor's supervision.

Sports

Athletes are advised not to indulge in certain sports while using this medicine. Archery, racing, shooting and other high-risk sports should be avoided. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency (WADA) which are not to be taken while participating in specific sports events.

Hyperthyroidism

This medicine should be administered with caution in patients with increased thyroid levels. Abrupt withdrawal of this medicine may lead to a life-threatening condition called thyroid-storm. Frequent monitoring of thyroid hormone levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

Use of this medicine may cause Azotemia (abnormal levels of nitrogen-containing products in the blood) in patients with a known history of severe renal disease. Close monitoring of kidney function is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Volume and electrolyte depletion

Use of this medicine may alter the blood volume levels and electrolytes levels. This may cause dizziness, dry mouth, and acid-base imbalance. Close monitoring of blood pressure and electrolytes levels is necessary while taking this medicine. Report any symptoms such as weakness, lethargy, muscle pain, drowsiness, dizziness, irregular heartbeat, etc. to the doctor immediately. Appropriate corrective measures and dose adjustments may be required based on the clinical condition.

Lupus Erythematosus

This medicine should be used with caution in patients with lupus erythematosus due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while receiving this medicine due to the increased risk of dizziness, fainting, and very low blood pressure. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Alprazolam

Amitriptyline

Cisapride

Diltiazem

Lithium

Amiodarone

Insulin

Theophylline

Diclofenac

Disease interactions

Asthma

This medicine is not recommended for use in patients with a history of asthma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.

Bradyarrhythmia/ AV Block

This medicine is not recommended for use in patients with Sinus Bradyarrhythmia or a heart block greater than the first degree due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.

Glaucoma

This medicine should be used with caution in patients with glaucoma because it may lower the intraocular pressure and worsen the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with a known history of diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is advised for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Pheochromocytoma

This medicine should be used with caution in patients with pheochromocytoma due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative should be considered under your doctor's supervision.

Hyperlipidemia

This medicine should be used with caution in patients with hyperlipidemia since it may further increase the blood triglycerides and cholesterol levels. Close monitoring of blood triglycerides and cholesterol levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Hyperparathyroidism

This medicine should be used with caution in patients with hyperparathyroidism due to the increased risk of worsening of the patient's condition. Close monitoring of blood calcium levels is recommended for such patients. Replacement with a suitable alternative may be required based on the clinical condition.

Hyperuricemia

This medicine should be used with caution in patients with hyperuricemia due to the increased risk of worsening of the patient's condition. Close monitoring of uric acid level is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
The desired effect of this medicine will not be achieved if taken together with multivitamin with minerals. You may need a dose adjustment or need to undergo special tests if these medicines are used together.
Avoid consumption of large amounts of orange juice with this medicine since it may decrease the effectiveness of the medicine.
Lab interactions

Thyroid function tests

Use of this medicine may decrease the serum protein-bound iodine levels. This factor should be taken into account when interpreting thyroid function tests' results. It is advised that you inform the doctor about all your current medicines including herbs and supplements before undergoing thyroid function tests.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as instructed by the doctor. You are advised to take this medicine before food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Atenolol relaxes the blood vessels and reduces the heart rate, promoting a smooth flow of the blood. Indapamide increases the excretion of water and sodium through the urine. Their combination is thus effective in reducing the blood pressure.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Thiazide diuretics, Cardioselective beta blockers

Schedule

Schedule H

Atenolol: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 10 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a684031.html

Indapamide - DrugBank [Internet]. Drugbank.ca. 2017 [cited 21 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00808

Indapamide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 21 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a684062.html

DailyMed - Atenolol- atenolol tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 10 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f36d4ed3-dcbb-4465-9fa6-1da811f555e6
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Information on this page was last updated on 16 Jul 2019

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