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Arilex 50 mg Capsule

Manufactured byAlembic Ltd.
ContainsDiacerein
Description

Arilex 50 mg Capsule is a medicine that belongs to the anthraquinone class and is used to treat the symptoms associated with degenerative diseases of the bones and joints. It is used to relieve pain and swelling associated with osteoarthritis. This medicine is slow acting and is used as a long-term treatment option for osteoarthritis.

Side effects

Major & minor side effects for Arilex 50 mg Capsule

  • Diarrhea
  • Stomach discomfort and pain
  • Nausea
  • Vomiting
  • Yellowing of skin and eyes
  • Intense yellow urine
  • Increase in liver enzyme levels
  • Allergic skin reaction

Uses of Arilex 50 mg Capsule

What is it prescribed for?

  • Osteoarthritis (Joint pain)
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine must be used only when necessary and the potential benefits outweigh the risks. This medicine should be taken only after consulting your doctor.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women as the risk of adverse effects on the nursing infant is significantly high. Your doctor will determine the best course of treatment based on your clinical condition.

Allergy

This medicine is not recommended for use if you have a known allergy to diacerein or any other inactive ingredients present in the formulation.

Severe kidney damage

This medicine is not recommended for use in patients having severe impairment of kidney function due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine must be used only when necessary and the potential benefits outweigh the risks. This medicine should be taken only after consulting your doctor.

Breast-feeding

This medicine is not recommended for use in breastfeeding women as the risk of adverse effects on the nursing infant is significantly high. Your doctor will determine the best course of treatment based on your clinical condition.
General warnings

Diarrhea

Use of this medicine may cause diarrhea or loose stools in the first few days of treatment. Contact your doctor if the complication is not resolved within 3-4 days.

Antibiotic therapy

This medicine should not be taken with antibiotics since the risk of gastric irritation and persistent diarrhea is significantly high in such cases. Your doctor may make appropriate changes to your therapy based on your clinical condition.

Diagnostic tests

It is recommended to monitor liver function, kidney function, complete blood count, and urine tests every six months during treatment with this medicine.

Intense yellowing of urine

Use of this medicine may cause intense yellow coloration of the urine. This is mainly due to the excretion of end products and may not be indicative of any complication.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose. Contact your doctor if you miss more than one scheduled dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Aluminium Hydroxide/Magnesium Hydroxide

Amoxycillin

Laxatives

Disease interactions

Irritable bowel syndrome

This medicine should be used with caution in patients having an irritable bowel or other associated conditions of the gastrointestinal tract due to an increase in the risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Kidney Disease

This medicine is not recommended for use in patients having severe impairment of the normal kidney function. Appropriate diagnostic tests must be performed to rule out any kidney disease before treatment with this medicine is initiated. Replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
A diet rich in dietary fibers and phytates may interfere with the absorption of this medicine. Hence, the administration of this medicine with a diet rich in fibers and phytates should be avoided. Your doctor/dietitian may suggest appropriate changes in your diet based on your clinical condition.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Contact your doctor if you experience prolonged diarrhea in the initial phase of treatment. Your doctor may also begin the treatment with a lower dose to minimize the side effects. Do not take this medicine in smaller or larger quantities than recommended. Do not stop taking this medicine before completion of the course/without consulting your doctor.
Miscelleneous

To be taken immediately after food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by blocking the actions of a certain specific protein that causes swelling, pain, and degradation of cartilage at bone joints.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Antirheumatics

Schedule

Schedule H

Diacerein - DrugBank [Internet]. Drugbank.ca. 2017 [cited 13 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB11994

Diacerein | C19H12O8 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 13 July 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/26248#section=Top

Pelletier JP e. Efficacy and safety of diacerein in osteoarthritis of the knee: a double-blind, placebo-controlled trial. The Diacerein Study Group. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2017 [cited 13 July 2017]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/11037895
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Information on this page was last updated on 8 Apr 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.