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Aricep-M Tablet
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Aricep-M Tablet

Manufactured byEISAI PHARMACEUTICALS INDIA LTD
ContainsMemantine (5 mg) + Donepezil (5 mg)
Description
Aricep-M Tablet is a combination of medicine, which is used for the treatment of moderate to severe dementia associated with Alzheimer's disease, a condition in which the patient's memory and ability to think, communicate, learn, and handle daily activities are impaired slowly. This medicine does not cure Alzheimer's disease; it improves the symptoms of the disease and delays disease progression.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Aricep-M Tablet

  • Diarrhea
  • Loss of appetite
  • Nausea and Vomiting
  • Muscle cramps
  • Frequent urination
  • Headache
  • Unusual bleeding
  • Joint pain
  • Shortness of breath
  • Hallucinations
  • Dizziness and Drowsiness
  • Irregular heart beat
  • Weight loss
  • Body pain

Uses of Aricep-M Tablet

What is it prescribed for?

  • Alzheimer's disease
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required by this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to memantine, donepezil, or any other inactive ingredients present along with the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Gastrointestinal bleeding and/or Peptic ulcer disease

This medicine is known to increase gastric acid secretion and may increase the risk of gastrointestinal bleeding. Inform the doctor if you have any symptoms of blood in stools and burning stomach. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizures

This medicine should be used with caution in patients who are suffering from seizures due to the increased risk of worsening of the condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Genitourinary conditions

This medicine should be used with caution in patients with genitourinary conditions due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Cardiovascular diseases

This medicine should be used with caution in patients with preexisting bradycardia or heart disease like heart failure, stroke, heart block, etc due to the increased risk of adverse effects. A fall in blood pressure, changes in the pulse, dizziness and other associated complications should be reported to the doctor on priority. It is advised to not take this medicine if the patient has recently suffered a heart attack. An alternative treatment option should be considered in some cases based on the clinical condition.

Use in children

This medicine is not recommended for use in children or adolescents since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carvedilol

Oxcarbazepine

Tramadol

Trihexyphenidyl

Trimethoprim

Disease interactions

Cardiovascular disease

This medicine should be used with caution in patients with preexisting bradycardia or heart disease like heart failure, stroke, heart block, etc due to the increased risk of adverse effects. A fall in blood pressure, changes in the pulse, dizziness and other associated complications should be reported to the doctor on priority. It is advised to not take this medicine if the patient has recently suffered a heart attack. An alternative treatment option should be considered in some cases based on the clinical condition.

Lung disease

This medicine should be used with caution in patients with lung disorders such as asthma or chronic obstructive pulmonary disease (COPD}. Monitoring respiratory function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hepatic impairment

This medicine should be used with caution in patients with severe liver impairment due to the increased risk of serious adverse effects. Monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Renal impairment

This medicine should be used with caution in patients who are suffering from kidney diseases due to the increased risk of adverse effects. Regular monitoring of the kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients who are suffering from seizures due to the increased risk of worsening of the condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Parkinson's disease

This medicine should be used with caution in patients with parkinsonism disorder, due to the increased risk of worsening of the condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine with or without food. Follow all the labeled instructions while taking this medicine. A caregiver has to monitor the drug intake by the patient. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Memantine decreases the abnormal activity in the brain by blocking the actions of a natural substance, glutamate. Donepezil works by increasing the level of acetylcholine. This helps in improving the symptoms of Alzheimer's disease.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

NMDA receptor antagonist, Cholinesterase inhibitors

Schedule

Schedule H

Donecept-M/ Donecept-M Forte Tablets [Internet]. CiplaMed. 2019 [cited 15 May 2019]. Available from:

https://ciplamed.com/content/donecept-m-donecept-m-forte-tablets

Memantine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 29 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a604006.html

DailyMed: Memantine Hydrochloride tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 29 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=be032f1e-c123-45a0-a345-a56be6fa43a6

Memantine: DrugBank [Internet]. Drugbank.ca. 2017 [cited 29 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB01043

Donepezil: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 22 May 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a697032.html
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Information on this page was last updated on 19 Jun 2019

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