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Apazine Plus Suspension

Manufactured byBIOTIC HEALTHCARE
ContainsAceclofenac (50 mg/5 ml) + Paracetamol (125 mg/5 ml)
Description

Apazine Plus Suspension is a combination medicine used for the treatment of pain and inflammation associated with conditions such as joint disorders, toothache, arthritis, etc. This medicine is recommended for use in children only.

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Side effects

Major & minor side effects for Apazine Plus Suspension

  • Gastric / Mouth Ulcer
  • Bloody and cloudy urine
  • Fatigue
  • Constipation
  • Diarrhea
  • Nausea and vomiting
  • Skin rash

Uses of Apazine Plus Suspension

What is it prescribed for?

  • Pain and inflammation
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within an hour of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 12 to 16 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to paracetamol, aceclofenac, any other NSAIDs, or any other inactive ingredients present along with these medicines.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers due to the increased risk of worsening of the patient's condition.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.

Asthma

This medicine is not recommended for use in patients with conditions like asthma due to the increased risk of respiratory dysfunction.

Gastro-intestinal bleeding

This medicine is not recommended for use in patients with a known history of gastrointestinal bleeding due to the increased risk of worsening of the patient's condition.

Cardiovascular Disease

This medicine is not recommended for use in patients with a known history of cardiovascular diseases due to the increased risk of worsening of the patient's condition.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Heart surgery

This medicine is not recommended for use in patients with a history of recent heart surgery due to the increased risk of worsening of the patient's condition.

Anemia

This medicine should be used with caution in patients with anemia due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Gastro-intestinal bleeding

This medicine may cause severe gastrointestinal bleeding and perforation after prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Bleeding disorders

This medicine should be used with extreme caution in patients with any bleeding disorders due to the increased risk of excessive bleeding. Report any unusual bruising or bleeding to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Alcohol-containing medicines

This medicine is not recommended for use if the patient is receiving any medicines containing alcohol due to the increased risk of severe adverse effects including dizziness, weakness, fever, rashes, etc. It is advised that you report all the patient's current medicines including any herbs and supplements to the doctor before beginning treatment with this medicine.

Missed Dose

Take/administer the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Lithium

Phenytoin

Sodium Nitrite

Leflunomide

Prilocaine

Digoxin

Corticosteroids

Antihypertensives

Anticoagulants

Disease interactions

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Impaired kidney function

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
Take/Administer this medicine with or without food. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesired side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Paracetamol increases the pain threshold and decreases swelling. Aceclofenac works by reducing the formation of certain substances in the body that causes pain and swelling. The combination is thus effective in relieving pain in several conditions.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Non-steroidal anti-inflammatory agents, Miscellaneous analgesics, Analgesic antipyretic combinations

Schedule

Schedule H

[Internet]. Bionova.co.in. 2018 [cited 31 August 2018]. Available from:

http://www.bionova.co.in/fenpill-plus-suspension.html

Acetaminophen | C8H9NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 22 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1983#section=Top

Aceclofenac - DrugBank [Internet]. Drugbank.ca. 2018 [cited 31 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB06736
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Information on this page was last updated on 12 Dec 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.