Anidulafungin

Description

Anidulafungin is used for the treatment of a type of fungal infection of the blood or other internal organs called invasive candidiasis. It is used to treat candida infections of the blood, esophagus, etc.

Side effects

Major & minor side effects for Anidulafungin

  • Convulsions (seizures)
  • Itching and skin rash
  • Wheezing
  • Low blood potassium
  • Diarrhea
  • Nausea and vomiting
  • Headache
  • Abnormal liver function
  • Kidney Impairment
  • Changes in blood pressure
  • Cholestasis
  • Increased blood sugar levels
  • Difficult and painful breathing
  • Unusual bleeding or bruising
  • Stomach pain
  • Pain at injection site
  • Muscle pain and cramps
  • Dry mouth

Uses of Anidulafungin

What is it prescribed for?

  • Esophageal Candidiasis
  • Candidemia
  • Invasive Candidiasis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains effective in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to anidulafungin, any other echinocandins, or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
General warnings

Other medicines

This medicine may interact with other medicines and may cause severe side effects. Hence, it is recommended that you report all your current medicines, including any herbs and supplements, to the doctor prior to receiving this medicine.

Pediatric use

This medicine is not recommended for use in patients less than 16 years of age since the safety and efficacy of use are not clinically established.

Liver diseases

This medicine should be used with caution in patients with a history of liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests is recommended for these patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the patient's clinical condition.

Other candida infections

This medicine is not recommended for the treatment of candida infections of the heart (endocarditis), bones (osteomyelitis), or the brain (meningitis) since the safety and efficacy of use are not clinically established.

Missed Dose

This medicine is usually administered in the hospital/clinical setting; hence, the likelihood of a missed dose is very low. If you miss a scheduled appointment for a dose of this medicine, contact your doctor immediately for further instructions.

Overdose

Since this medicine is administered in the hospital/clinical setting, the likelihood of an overdose is very low. However, if an overdose is suspected, emergency medical treatment will be instituted by your doctor.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Liver Disease

This medicine should be administered with caution in patients with an impairment of normal liver function due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests is recommended for these patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is administered in a hospital/clinical setting by a qualified healthcare professional. Follow all instructions given by your doctor. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines including any herbs and supplements as well as your medical conditions before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine interferes with the formation of a vital component of the fungal cell wall. This results in the death of the fungi.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Echinocandins

Schedule

Schedule H

Anidulafungin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 12 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Anidulafungin#section=Top

Anidulafungin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 12 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00362

[Internet]. 2018 [cited 12 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021632s002lbl.pdf

[Internet]. Medicines.org.uk. 2018 [cited 12 September 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.454.pdf

DailyMed - Anidulafungin injection, powder, lyophilized, for solution [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 12 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a88d9010-55fb-4a02-baff-042cd27688ea

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Information on this page was last updated on 17 Sep 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.