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Amphy-1500 Injection

Manufactured byPROFIC ORGANIC LTD
ContainsAmpicillin (1000 mg) + Sulbactam (500 mg)
Description

Amphy-1500 Injection is a combination medicine which may be used to treat bacterial infections in lungs, heart, brain, genital areas, etc. caused by susceptible bacteria. It should be used with caution in patients with kidney diseases due to the increased risk of adverse effects.

Side effects

Major & minor side effects for Amphy-1500 Injection

  • Injection site pain
  • Diarrhea
  • Chest pain
  • Chills
  • Difficult or painful urination
  • Redness of skin

Uses of Amphy-1500 Injection

What is it prescribed for?

  • Bacterial infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed rapidly after an intravenous or intramuscular administration.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to ampicillin, sulbactam, other beta-lactam antibiotics, or any other inactive ingredients present in the formulation.

Liver Disease

This medicine is not recommended for use in patients with a known history of jaundice or liver function impairment associated with the use of ampicillin-sulbactam due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Liver Disease

This medicine should be used with extreme caution in patients with liver diseases due to the increased risk of adverse effects. Regular monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Drug Resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Skin Reactions

This medicine should be used with caution since it may increase the risk of serious skin reactions such as Stevens-Johnson syndrome, Toxic epidermal necrolysis, etc. Report any unusual symptoms to the doctor on priority. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Clostridium difficile-associated Diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Mononucleosis

This medicine is likely to cause rashes and bumps on the skin if the patient is suffering from Mononucleosis. Usage of this medicine is not recommended in such cases. An alternative treatment option should be considered in some cases based on the clinical condition.

Electrolyte imbalance

This medicine should be used with caution in patients with a known history of electrolyte imbalance since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of electrolyte levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Epilepsy

This medicine should be used with caution in patients with a known history of epilepsy due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Live cholera vaccine

Atenolol

Methotrexate

Doxycycline

Lansoprazole

Warfarin

Disease interactions

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Colitis

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesired side effects to the doctor promptly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Ampicillin interferes with the bacterial cell wall formation and stops the growth of bacteria. Sulbactam inhibits some chemicals produced by the bacteria and makes the bacteria more sensitive to ampicillin activity.
Legal Status

Unknown

Approved

Unknown

Unknown

Classification

Category

Aminopenicillins, Beta-lactamase inhibitors

Schedule

Schedule H

DailyMed - Ampicillin sodium injection, powder, for solution [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 16 April 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=da8da9c0-fa46-40d3-82c6-1a18ffa1b585

Ampicillin Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2019 [cited April 2019]. Available from:

https://medlineplus.gov/druginfo/meds/a601133.html

Sulbactam - DrugBank [Internet]. Drugbank.ca. 2019 [cited April 2019]. Available from:

https://www.drugbank.ca/drugs/DB09324
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Information on this page was last updated on 4 Jul 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.