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Tolpazen Tablet
Manufactured byMICRO LABS LTD
ContainsAceclofenac (100 mg) + Trypsin (48 mg) + Bromelain (90 mg) + Rutoside (100 mg)
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Description
Tolpazen Tablet is a combination of pain reliever and proteolytic enzymes that are used in reducing pain and swelling associated with various musculoskeletal disorders. It provides effective relief from pain and swelling due to ankylosing spondylitis and arthritis namely, osteoarthritis and rheumatoid arthritis. It is also used to provide relief from headaches, toothaches, backaches, menstrual pain, sprains, and strains.
You may experience certain side effects such as nausea, vomiting, heartburn, stomach upset, loss of appetite, and diarrhoea. Do not use Tolpazen Tablet if you are previously allergic to it. Use it cautiously in individuals with liver and kidney problems.
Take Tolpazen Tablet with or without food and drink adequate water. For the ease of remembering, take it at around the same time every day. Tolpazen Tablet relieves pain and swelling due to arthritic conditions but does not cure it.
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Substitutes
List of substitutes for Tolpazen Tablet
Side effects
Major & minor side effects for Tolpazen Tablet
Stomach discomfort
Constipation
Diarrhoea
Nausea and vomiting
Skin rash
Severe allergic reaction
Increased blood pressure
Uses of Tolpazen Tablet
What is it prescribed for?
Pain and inflammation
Pain and inflammation (swelling) is a very common condition in everyone that occurs as part of your body's immune response to protect the body from infection, injury, or disease. Tolpazen Tablet is used to relieve swelling and pain associated with conditions like back pain, muscle soreness, arthritis-related pain, sprain, strain, menstrual cramps, injury, toothaches and headaches.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
Tolpazen Tablet provides relief from pain and swelling within 1 to 2 hours of administration.How long do the effects of this medicine last?
The duration of action for Tolpazen Tablet is 6 to 8 hours. You may have to take your next dose if your pain continues.Is it safe to consume alcohol while taking this medicine?
Consumption of alcohol is not recommended while treatment with Tolpazen Tablet due to the risk of stomach bleeding.Is this a habit forming medicine?
No habit-forming tendencies were reported for Tolpazen Tablet.Can this medicine be taken during pregnancy?
Tolpazen Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your baby. But in some cases, your doctor may prescribe this medicine if the benefits outweigh the risks. All the risks and benefits should be discussed with your doctor before using this medicine.Can this medicine be taken while breast-feeding?
Tolpazen Tablet is not recommended for use in breastfeeding women. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. If required, it should only be used upon your doctor's recommendation.
Allergy
Avoid taking Tolpazen Tablet if you are previously allergic to it. Allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms of serious allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.
Asthma
Asthma is a condition in which your airways get narrow and swell and may produce extra mucus. Tolpazen Tablet is not recommended for use in patients with known conditions such as NSAID-induced asthma, rhinitis, urticaria, etc. due to the increased risk of worsening of the patient's condition.
Bleeding disorder
Tolpazen Tablet may prolong the blood clotting time and therefore increase the risk of bleeding. Hence avoid using it due to worsening of the patient's condition.
Warnings for special population
Pregnancy
Tolpazen Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your baby. But in some cases, your doctor may prescribe this medicine if the benefits outweigh the risks. All the risks and benefits should be discussed with your doctor before using this medicine.
Breast-feeding
Tolpazen Tablet is not recommended for use in breastfeeding women. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. If required, it should only be used upon your doctor's recommendation.
General warnings
Heart surgery
Tolpazen Tablet is not recommended for use in patients with a history of recent heart surgery due to the increased risk of worsening of the patient's condition.
Kidney/Liver disease
Caution is advised while using Tolpazen Tablet in patients with liver/kidney disease due to an increase in the risk of kidney toxicity and metabolic disorders.
Driving or operating machinery
Tolpazen Tablet may rarely cause dizziness, blurred vision, or drowsiness and hence do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms.
Use in children
Tolpazen Tablet is not recommended in children below 18 years of age unless directed by a doctor.
Missed Dose
Try not to skip the scheduled dose of Tolpazen Tablet. And if a dose is skipped, do not add it up to the next dose.
Overdose
Seek emergency medical attention in case of an overdose with Tolpazen Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended while treatment with Tolpazen Tablet due to the risk of stomach bleeding.
Interaction with Medicine
Lithium
Digoxin
Corticosteroids
Antihypertensives
Disease interactions
Asthma
Patients with asthma may experience allergic reactions while taking Tolpazen Tablet. Hence it is not recommended for use in patients with asthma, especially those who had experienced allergic reactions with the use of non-steroidal anti-inflammatory medicines.
Gastro-Intestinal toxicity
Long term use of Tolpazen Tablet can cause damage to the stomach and intestine. Serious conditions like bleeding, ulceration, and perforation of the stomach or intestinal wall can occur.
Kidney disease
Prolonged use of high doses of Tolpazen Tablet may cause kidney problems, such as painful urination and protein or blood in the urine. Hence this medicine should be used cautiously in kidney impaired patients. Close monitoring of kidney function is necessary while receiving this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Tolpazen Tablet with or without food. Drink plenty of water. Never take more than the prescribed dose of this medicine. Do not give your medicine to other people even if their condition appears to be the same as yours.
Miscelleneous
How it works
Trypsin and Bromelain are proteolytic enzymes that help in the breakdown of proteins involved in swelling and pain.
Rutoside is an antioxidant that protects the body from damage by chemicals causing swelling.
Aceclofenac stops the release of a chemical called prostaglandins, that increase pain and swelling. Thus, this medicine provides relief from your aches and makes you feel better.
Legal Status
Classification
Category
Miscellaneous analgesics
Schedule
Schedule H
Go.drugbank.com. 2021. Rutin | DrugBank Online. [online] Available at: < [Accessed 20 April 2021].
Allengeindia.com. 2021. [online] Available at: < [Accessed 22 June 2021].
Delcure.com. 2021. Delpoflex A – Delcure. [online] Available at: < [Accessed 22 June 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Tryptase. [online] Available at: < [Accessed 20 April 2021].
Go.drugbank.com. 2021. Bromelains | DrugBank Online. [online] Available at: < [Accessed 20 April 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Bromelain. [online] Available at: < [Accessed 20 April 2021].
Go.drugbank.com. 2021. Trypsin | DrugBank Online. [online] Available at: < [Accessed 20 April 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Aceclofenac. [online] Available at: < [Accessed 7 May 2021].
Drugbank.ca. 2021. Aceclofenac | DrugBank Online. [online] Available at: < [Accessed 7 May 2021].
Information on this page was last updated on 2 Jul 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.
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