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Sodium Hyaluronate
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Description
Sodium Hyaluronate is used in various dosage forms for different indications. Sodium Hyaluronate injection is used to relieve pain in conditions like osteoarthritis (pain on movement due to wearing of the protective covering at the ends of the bones).
Sodium Hyaluronate cream is used to treat skin conditions such as bedsores, diabetic foot ulcers, burn wounds, surgical incisions, dry or scaly skin, cuts, skin irritations, etc. Sodium Hyaluronate eye drops are used to prevent eye dryness. It may also be used during eye surgeries to protect eye tissues from stress.
Sodium Hyaluronate may cause side effects like headache, pain at the injection site, skin irritation and discolouration, eye pain and discomfort etc. Most of these side effects are temporary and resolve on their own. Consult your doctor if these side effects are persistent. Avoid driving vehicles after using Sodium Hyaluronate eye drops as it can change your eyesight.
Sodium Hyaluronate injection is given by a qualified healthcare professional in a hospital or clinic. Sodium Hyaluronate cream is applied as a thin layer on the affected area, as prescribed by your doctor. Sodium Hyaluronate eye drops are instilled over your eyes, as prescribed by your doctor. Your dose will be dependent on the severity of your condition. Do not stop using this medicine without consulting your doctor as your symptoms may reoccur.
Sodium Hyaluronate is not recommended if you are allergic to it. Inform your doctor about all your current medications and existing medical conditions. This can help your doctor to adjust your dose to avoid side effects. If you are pregnant or are breastfeeding, consult your doctor before using this medicine.
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Side effects
Major & minor side effects for Sodium Hyaluronate
Diarrhoea
Headache
Itching of skin
Loss of appetite
Stomach pain
Swelling of the knee
Swelling of eyelids, face, lips
Injection site pain
Fever
Skin discoloration
Weakness
Change in eyesight
Eye pain
Eye irritation
Uses of Sodium Hyaluronate
What is it prescribed for?
Osteoarthritis
Osteoarthritis is a type of joint disorder that occurs when the protective cartilage, that cushions the ends of your bones wears down over time. Sodium Hyaluronate injection is used to relieve symptoms such as pain and stiffness associated with osteoarthritis in people who fail to achieve adequate relief from painkillers or from exercise and physical therapy.
Skin conditions
Sodium Hyaluronate cream is used for the dressing and management of various skin conditions like burns, sores, ulcers, wounds including cuts and abrasions, and other irritations of the skin. This medicine does not treat the root cause of your skin conditions. It is used to cover a wound or burn on your skin and protect it against friction, and dryness.
Dry eyes
Dry eyes is a common condition that occurs when your tears are not able to provide adequate lubrication for your eyes. Sodium Hyaluronate eye drops are used to prevent as well as treat dryness of your eyes.
Concerns
Commonly asked questions
Onset of action
The amount of time taken by Sodium Hyaluronate to show its effect is subject to vary based on the dose strength and the form of administration.Duration of effect
The amount of time for which Sodium Hyaluronate remains effective is subject to vary based on the dose strength and the form of administration.Safe with alcohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is it habit forming?
No habit-forming tendencies were reported for Sodium Hyaluronate.Usage in pregnancy?
Sodium Hyaluronate is not recommended for use in pregnancy as there are not enough studies done to understand its safety and efficacy. Consult with your doctor before using this medicine.Usage while breast-feeding?
It is not known whether Sodium Hyaluronate passes into breast milk or if it could harm the infant. Inform your doctor if you are breastfeeding before using this medicine.
Allergy
Sodium Hyaluronate is not recommended if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.
Joint infection
Sodium Hyaluronate is not recommended for use if you have an injection in your joints as it can increase the risk of spreading the infection. This can worsen your condition.
Warnings for special population
Pregnancy
Sodium Hyaluronate is not recommended for use in pregnancy as there are not enough studies done to understand its safety and efficacy. Consult with your doctor before using this medicine.
Breast-feeding
It is not known whether Sodium Hyaluronate passes into breast milk or if it could harm the infant. Inform your doctor if you are breastfeeding before using this medicine.
General warnings
Inflammation
Sodium Hyaluronate may cause swelling in your knee. Your doctor may advise you to rest your knee or apply ice for a short time after the injection. If the symptoms are severe, contact your doctor immediately for further instructions.
Strenuous activities
You are recommended to avoid strenuous activities such as jogging, tennis, heavy lifting, standing on your feet for a long time, etc. for at least 48 hours after receiving Sodium Hyaluronate in the knee.
Joint effusion
Joint effusion is a condition involving an excessive amount of fluid in or around a joint, usually the knee. If you have joint effusion, your doctor will treat that first before receiving Sodium Hyaluronate as it may worsen your condition.
Blurring of vision
Sodium Hyaluronate can cause temporary blurring of vision and hence you should refrain from driving vehicles or operating machines immediately after using this medicine.
Skin irritation
Any instance indicative of allergic reactions or skin irritation while using Sodium Hyaluronate should be reported to your doctor immediately. Appropriate corrective measures or replacements with a suitable medicine may be necessary in some cases.
Missed Dose
Injection: As Sodium Hyaluronate is given by a qualified healthcare professional in the clinical/hospital setting, the likelihood of missing a dose is very low.
Eye drops/Topical forms: Apply the missed dose of Sodium Hyaluronate as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Injection: As Sodium Hyaluronate is given in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by your doctor if an overdose is suspected.
Eye drops/Topical forms: Seek emergency medical treatment in case of an overdose of Sodium Hyaluronate.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Benzalkonium chloride
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Injection: Sodium Hyaluronate should be given by a qualified healthcare professional.
Inform the doctor if you are allergic to this medicine.
Inform your doctor about all your current medicines including herbs and supplements as well as all your medical conditions before receiving this medicine.
Eye drops: Use Sodium Hyaluronate exactly as advised by your doctor.
Do not use in larger or smaller amounts than prescribed.
Consult your doctor if you experience any undesirable side effects.
Ensure that the treatment course is completed.
Do not stop the use of this medicine without consulting your doctor.
Topical forms: Apply a thin layer of Sodium Hyaluronate exactly as advised by your doctor.
Do not apply in larger or smaller amounts than prescribed.
Consult your doctor if you experience any undesirable side effects.
Ensure that the treatment course is completed.
Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
When used for osteoarthritis, Sodium Hyaluronate acts as a lubricant and helps the joints to work properly, thereby lessening the pain.
Sodium Hyaluronate cream acts as a skin lubricant, moisturizer, and shock absorber; it also has a protective effect.
Sodium Hyaluronate eye drops prevent eye dryness.
When used during eye surgeries, this medicine protects eye tissues from mechanical stress.
When used in plastic surgery, it combines with water and swells, causing a smoothing or filling effect to reduce wrinkles or folds on the face.
Legal Status
Classification
Category
Viscosupplementation agents, Topical agents, Ophthalmic lubricants, Dermal fillers
Schedule
Schedule H
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U.S. Food and Drug Administration. 2021. FDA-Approved Dermal Fillers. [online] Available at: < [Accessed 2 November 2021].
Santen Pharmaceutical Co., L., 2021. Hyalein®/Hialid®/Sanlein® | Dry Eye | Asia | For Patients | Santen Pharmaceutical. [online] Santen.com. Available at: < [Accessed 2 November 2021].
Dailymed.nlm.nih.gov. 2021. [online] Available at: < [Accessed 2 November 2021].
Rad-ar.or.jp. 2021. Search results detail| Kusurino-Shiori(Drug information Sheet). [online] Available at: < [Accessed 2 November 2021].
Information on this page was last updated on 17 Nov 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.