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R-Cinex 600 Tablet
Manufactured byLUPIN LTD
ContainsRifampicin (600 mg) + Isoniazid (300 mg)
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Description
R-Cinex 600 Tablet is a combination of Rifampicin and Isoniazid. This medicine is used for the treatment of tuberculosis (a bacterial infection that affects your lungs). It prevents the bacteria from growing, thus it helps in treating the infection.
R-Cinex 600 Tablet might cause some side effects like nausea, vomiting, headache, heartburn, etc., that subside with time. Avoid consuming alcohol while you are on treatment with this medicine because it may cause excessive drowsiness. Inform your doctor if any of the side effects become severe or persist for a long time.
R-Cinex 600 Tablet is recommended to be taken on an empty stomach. Abrupt discontinuation may cause the infection to reappear. It may take some time for the medication to show its effects. However, if you notice a worsening of your condition or if it does not improve, consult your doctor.
R-Cinex 600 Tablet should be used with caution if you have liver and stomach/intestinal problems. Inform your doctor about any other medications you are taking because some may interact with or be impacted by this medication. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.
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Substitutes
List of substitutes for R-Cinex 600 Tablet
Side effects
Major & minor side effects for R-Cinex 600 Tablet
Dark urine
Loss of appetite
Nausea or Vomiting
Unusual tiredness or weakness
Tingling or numbness of the hands and feet
Convulsions (seizures)
Depression
Joint pain
Skin Rash
Unusual bleeding or bruising
Abdominal pain
Dizziness
Headache
Yellow colored eyes or skin
Muscle pain
Uses of R-Cinex 600 Tablet
What is it prescribed for?
Tuberculosis
Tuberculosis is a contagious infection that mainly affects your lungs. It can also spread to other parts of your body, such as the brain and spine. R-Cinex 600 Tablet is used in the treatment of tuberculosis. It kills as well as prevents the activity of the bacteria. Thus, helps in the treatment of the infection.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The amount of time required for R-Cinex 600 Tablet to show its action is not clinically established.How long do the effects of this medicine last?
The amount of time for which R-Cinex 600 Tablet remains active in your body is not clinically established.Is it safe to consume alcohol while taking this medicine?
Avoid drinking alcohol while on treatment with R-Cinex 600 Tablet as it may increase the risk of side effects such as dizziness, flushing, increased heartbeat, nausea, thirst, etc.Is this a habit forming medicine?
No habit-forming tendencies were reported for R-Cinex 600 Tablet.Can this medicine be taken during pregnancy?
R-Cinex 600 Tablet is not recommended for use if you are pregnant. It may cause harm to your foetus; hence, consult your doctor before using it.Can this medicine be taken while breast-feeding?
R-Cinex 600 Tablet passes into breastmilk. Thus, it is not recommended for use if you are breastfeeding.
Allergy
If you have a known allergy to R-Cinex 600 Tablet, avoid this medication. Seek immediate medical attention if you notice any symptoms of allergic reactions such as a skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.
Antiviral medications
R-Cinex 600 Tablet is not recommended for use if you are receiving antiviral treatment This medicine can decrease the effectiveness of antiviral medicines and may lead to viral resistance.
Severe liver impairment
R-Cinex 600 Tablet should be used with caution if you have any liver conditions. This medicine is broken down in your liver, and improper liver function can lead to the accumulation of this medicine in your body. This may worsen your condition.
Warnings for special population
Pregnancy
R-Cinex 600 Tablet is not recommended for use if you are pregnant. It may cause harm to your foetus; hence, consult your doctor before using it.
Breast-feeding
R-Cinex 600 Tablet passes into breastmilk. Thus, it is not recommended for use if you are breastfeeding.
General warnings
Kidney impairment
R-Cinex 600 Tablet should be used with caution if you have any medical conditions affecting your kidneys. Any kidney dysfunction can lead to its accumulation of the medicine in your body. This may worsen your condition.
Diabetes
R-Cinex 600 Tablet should be used with caution if you have diabetes (a condition in which the blood sugar level increases). This medicine may alter your blood sugar levels and affect the management of diabetes.
Drug-resistance
Usage of R-Cinex 600 Tablet without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of the development of bacteria that are drug-resistant.
Use in children
R-Cinex 600 Tablet is not recommended for use in children below 15 years of age due to the lack of safety and efficacy of its use.
Liver enzymes
R-Cinex 600 Tablet may elevate liver enzyme levels. Use it with caution and get your liver function tests done regularly.
Missed Dose
If you have missed R-Cinex 600 Tablet dose, make sure that you remember to take the next dose on time. Do not take two doses together to make up for a missed dose.
Overdose
Never take R-Cinex 600 Tablet more than the prescribed dose. If you suspect that you have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Avoid drinking alcohol while on treatment with R-Cinex 600 Tablet as it may increase the risk of side effects such as dizziness, flushing, increased heartbeat, nausea, thirst, etc.
Interaction with Medicine
Clopidogrel
Propranolol
Warfarin
Live cholera vaccine
Atorvastatin
Disease interactions
Colitis
Colitis is swelling of the colon (a part of your intestine). R-Cinex 600 Tablet should be used with caution if you have colitis. This medicine may cause the infection to flare up, thus can worsen your condition.
Hematopoietic disturbances
Hematopoietic disturbances are disorders that primarily affect the blood & blood-forming organs like bone marrow. Take R-Cinex 600 Tablet with extreme caution as it may worsen your condition.
Porphyria
Porphyria is a blood disorder that is caused due to build-up of certain chemicals related to red blood cell proteins. Take R-Cinex 600 Tablet with extreme caution as it may worsen your condition.
Food interactions
R-Cinex 600 Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal because food decreases the absorption of this medicine.
Lab interactions
Information not available.
Take R-Cinex 600 Tablet on an empty stomach, either one hour before or two hours after a meal.
Do not consume in larger or smaller amounts than advised.
Consult your doctor if you experience any undesirable effects.
It may cause discolouration (yellow, orange, red, brown) of your teeth, urine, sweat, sputum, and tears. Soft contact lenses may be permanently stained. This is normal and not harmful.
Miscelleneous
How it works
R-Cinex 600 Tablet is a combination of two medicines, Rifampicin and Isoniazid. Rifampicin acts by blocking the action of a bacterial component, which is necessary for tuberculosis bacteria to multiply. Isoniazid prevents the growth of the protective layer of these bacteria. They work together to kill the bacteria and treat the infection.
Legal Status
Classification
Category
Antituberculosis combinations
Schedule
Schedule H
Drugs, H., 2021. Isoniazid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 31 August 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Isoniazid. [online] Available at: [Accessed 31 August 2021].
Dailymed.nlm.nih.gov. 2021. RIFAMATE® (rifampin and isoniazid capsules USP). [online] Available at: [Accessed 31 August 2021].
Accessdata.fda.gov. 2021. [online] Available at: [Accessed 24 August 2021].
Drugs, H., 2021. Rifampin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 31 August 2021].
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Please
Yes you can take water
No problem for absorption of medicines
Information on this page was last updated on 14 Mar 2023
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.