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Pyrantel Pamoate

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Description

Pyrantel Pamoate is an anthelmintic or anti-worm medicine used to treat infections caused by worms such as pinworm, hookworm, and roundworm. This medicine is not recommended for use in patients below 2 years of age.
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Side effectsConcernsUsage

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Side effects

Major & minor side effects for Pyrantel Pamoate

Nausea and Vomiting

Diarrhea

Abdominal cramps

Headache

Skin rash

Drowsiness

Sleep disturbances

Elevated liver enzymes

Dizziness

Uses of Pyrantel Pamoate

What is it prescribed for?

Ascariasis

This medicine is used for the treatment of ascariasis, which is an infection of the intestine caused by the roundworms (Ascaris lumbricoides).

Pinworm infection

This medicine is used for the treatment of pinworm infection (Enterobius).

Hookworm infection

This medicine is used for the treatment of hookworm infection (Ancylostoma or Necator).

Trichostrongyliasis

This medicine is used for the treatment of trichostrongyliasis, which is an infection caused by a species of Trichostrongylus.
Concerns

Commonly asked questions

  • Onset of action

    The peak effect of this medicine can be observed within 1-3 hours of administration of the dose.

  • Duration of effect

    The duration for which this medicine remains active in the body is not clinically established.

  • Safe with alcohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit-forming tendencies were reported.

  • Usage in pregnancy?

    This medicine is not recommended for pregnant women unless necessary. The risk and benefits should be discussed with the doctor before receiving this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to pyrantel pamoate or any other inactive ingredients present along with it.

Severe Hepatic impairment

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.

Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women unless necessary. The risk and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

General warnings

Malnurition (or) Anemia

This medicine should be used with caution in patients with severe malnutrition or anemia. Ideally, anemic, dehydrated, or malnourished patients should receive supportive therapy prior to administration of this medicine.

Use in children

The use of this medicine is not recommended in children less than 2 years of age since the safety and efficacy has not been established.

Liver disorder

This medicine should be used with caution in patients with preexisting or active mild to moderate liver diseases due to the increased risk of adverse effects. Regular monitoring of the liver function tests is necessary while receiving this medicine. Initiation of the therapy with this medicine at low doses is advised. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience dizziness during treatment with this medicine.

Missed Dose

Usually, this medicine is given as a single dose, so take the medicine as soon as you remember. In case of multiple dose regimen, if it’s almost time for your next dose, skip the missed dose and contact your doctor for further instructions. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Sodium iodide (I-123 and I-131)

Disease interactions

Disease

Information not available.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as advised by the doctor. Do not take in larger quantities than advised. Do not take if you have an allergy to this medicine. Inform the doctor if you develop any undesired effects.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

It works by paralyzing the parasite and disrupting its attachment to the host intestine.

Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Anthelmintics

Schedule

Schedule H

[Internet]. Dailymed.nlm.nih.gov. 2018 [cited 24 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b810b184-047a-442e-9de0-67df043fabca

[Internet]. Drugbank.ca. 2018 [cited 24 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB11156

[Internet]. Rad-ar.or.jp. 2018 [cited 24 September 2018]. Available from:

http://www.rad-ar.or.jp/siori/english/kekka.cgi?n=39043
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Information on this page was last updated on 29 Jan 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.