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Pregal-M 50 Capsule
Manufactured byPrescripto Life Sciences
ContainsPregabalin (50 mg) + Methylcobalamin (750 mcg)
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Description
Pregal-M 50 Capsule is a combination of Pregabalin and Methylcobalamin. It is used in the treatment of neuropathic pain (pain caused due to injury or damage to the nerve). It relieves pain by reducing the release of certain chemicals that send pain signals throughout your body. It also helps to repair the damaged nerves.
Pregal-M 50 Capsule may cause side effects like nausea, dry mouth, swelling in your arms or feet, weight gain, weakness, and confusion. These symptoms may subside by themselves. However, consult your doctor if these side effects persist or worsen. Avoid driving vehicles or operating heavy machines as it may cause drowsiness.
Pregal-M 50 Capsule may be taken with or without food. Take it at the same time every day for better results. Your doctor will determine the dose and duration of treatment based on your condition. Never take more than the prescribed dose. Avoid the discontinuation of this medicine without consulting your doctor as it may lead to withdrawal symptoms like headache, mood swings, irritation, etc.
Pregal-M 50 Capsule should be avoided if you are allergic to it. Inform your doctor if you have kidney or heart problems. It is not recommended for use in children below 18 years of age as there are no safety and efficacy data established. Consult your doctor if you are pregnant, or are breastfeeding before taking this medicine.
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Substitutes
List of substitutes for Pregal-M 50 Capsule
Side effects
Major & minor side effects for Pregal-M 50 Capsule
Difficulty in breathing
Chest tightness
Swelling of face, lips, eyelids, tongue, hands and feet
Blurred vision
Dizziness
Headache
Loss of bladder control
Confusion
Nervousness
Nausea and vomiting
Weakness
Drowsiness
Uses of Pregal-M 50 Capsule
What is it prescribed for?
Peripheral Neuropathy
Peripheral neuropathy is a condition that occurs due to damage of the peripheral nerves (nerves located outside of the brain and spinal cord). It often causes weakness, numbness, and pain, usually in the hands and feet. Pregal-M 50 Capsule is used in the treatment of peripheral neuropathy.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The time Pregal-M 50 Capsule takes to show its action is not known.How long do the effects of this medicine last?
The amount of time for which Pregal-M 50 Capsule remains effective in your body is not known.Is it safe to consume alcohol while taking this medicine?
Avoid consumption of alcohol during treatment with Pregal-M 50 Capsule. It may increase the risk of side effects like dizziness, drowsiness, and impaired ability to think. Hence, avoid performing activities that require mental alertness like driving vehicles or operating machines until you know how this medicine affects you.Is this a habit forming medicine?
Pregal-M 50 Capsule has a low abuse potential with limited physical and psychological dependence.Can this medicine be taken during pregnancy?
Pregal-M 50 Capsule is not recommended during pregnancy unless necessary. If you are pregnant, consult your doctor before taking this medicine.Can this medicine be taken while breast-feeding?
Pregal-M 50 Capsule is not recommended for use while breastfeeding as it may pass into breastmilk. If you are breastfeeding, consult your doctor before taking this medicine.
Allergy
Avoid taking Pregal-M 50 Capsule if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Leber's Disease
Leber's Disease is an inherited eye disorder that may lead to loss of vision. The symptoms include pain in the eye, blurring or clouding of vision, or loss of ability to complete visual tasks like reading, driving, etc. Pregal-M 50 Capsule is not recommended for use if you have this rare eye condition.
Warnings for special population
Pregnancy
Pregal-M 50 Capsule is not recommended during pregnancy unless necessary. If you are pregnant, consult your doctor before taking this medicine.
Breast-feeding
Pregal-M 50 Capsule is not recommended for use while breastfeeding as it may pass into breastmilk. If you are breastfeeding, consult your doctor before taking this medicine.
General warnings
Driving or operating machines
Pregal-M 50 Capsule may increase the risk of drowsiness, dizziness, difficulty concentrating, etc. Hence, avoid performing activities such as driving vehicles or operating machines if you experience any of these symptoms.
Withdrawal symptoms
Sudden discontinuation of Pregal-M 50 Capsule may lead to withdrawal symptoms such as irritability, mood swings, depression, nervousness, convulsions (fits), etc. Do not stop the use of this medicine without consulting your doctor.
Kidney disease
Pregal-M 50 Capsule is filtered by the kidneys. Hence, use this medicine with caution if you have kidney problems as it may cause further kidney damage. Your doctor may suggest tests to monitor the kidney function while you are taking this medicine.
Suicidal tendencies
Pregal-M 50 Capsule may increase the risk of suicidal thoughts or behaviour. Hence, close observation for change in mood or behaviour is necessary while you are taking this medicine.
Heart disease
Use Pregal-M 50 Capsule with caution if you have heart problems as it may cause abnormal heart rhythm which could result in further complications. This medicine may also cause retention of fluid in your body and increase the risk of heart failure. It is more likely to occur in the elderly with compromised heart function. Hence, your doctor will closely monitor the functioning of your heart during treatment with this medicine.
Potential for abuse
Pregal-M 50 Capsule may cause dependency (being habituated to the medicine, unable to function normally without it), especially if you have used other recreational medicines (medicines used for enjoyment and leisure purposes rather than for medical reasons) in the past. Inform your doctor if you had a history of substance abuse before taking this medicine.
High creatinine kinase levels
Myopathy is a condition in which the muscles do not function properly leading to muscle weakness. Use Pregal-M 50 Capsule with caution in such conditions as it may cause an increase in the creatine kinase levels. Thus, it may worsen your condition.
Use in Children
Pregal-M 50 Capsule is not recommended for use in children below 18 years of age as the safety and efficacy data are not clinically established.
Missed Dose
Take the missed dose of Pregal-M 50 Capsule as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose
Never take more than the prescribed dose. Seek emergency medical treatment in case of an overdose of Pregal-M 50 Capsule.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Avoid consumption of alcohol during treatment with Pregal-M 50 Capsule. It may increase the risk of side effects like dizziness, drowsiness, and impaired ability to think. Hence, avoid performing activities that require mental alertness like driving vehicles or operating machines until you know how this medicine affects you.
Interaction with Medicine
Buprenorphine
Oxycodone
Propoxyphene
Pioglitazone
Lorazepam
Ramipril
Disease interactions
Angioedema
Angioedema is the swelling of the inner layer of your skin. Pregal-M 50 Capsule may increase the risk of angioedema. Hence, use this medicine with caution if you have a history of angioedema. Your doctor may prescribe an alternative medicine based on your clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Pregal-M 50 Capsule may be taken with or without food. Do not break, chew, or crush the capsule.
Take this medicine for the recommended duration. Avoid taking more or less than the prescribed dose.
Take this medicine at the same time every day for the ease of remembering.
Inform your doctor if your symptoms do not improve or if you experience any side effects that persist or worsen.
Avoid consumption of alcohol during treatment with this medicine as it may increase the risk of side effects.
Inform your doctor immediately if you experience a change in behaviour or suicidal thoughts.
Miscelleneous
How it works
Pregal-M 50 Capsule is a combination of Pregabalin and Methylcobalamin.
Pregabalin works by reducing the levels of certain chemical substances in the brain and preventing the transmission of pain signals.
Methylcobalamin helps in the production of myelin (a substance that protects the nerve fibres) and repairs the damaged nerve cells.
Legal Status
Classification
Category
Gamma-aminobutyric acid analogs, Vitamins
Schedule
Schedule H
Dailymed.nlm.nih.gov. 2021. DailyMed - PREGABALIN capsule. [online] Available at: [Accessed 12 August 2021].
Drugs, H., 2021. Pregabalin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 12 August 2021].
Ods.od.nih.gov. 2021. Office of Dietary Supplements - Vitamin B12. [online] Available at: [Accessed 12 August 2021].
Accessdata.fda.gov. 2021. [online] Available at: [Accessed 20 September 2021].
Medicines.org.uk. 2021. Pregabalin 150 mg capsules, hard - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 25 August 2021].
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Information on this page was last updated on 18 Jan 2023
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.