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Description
Pirfenex Tablet is a medicine used to treat idiopathic pulmonary fibrosis (a chronic, progressive condition that causes thickening, stiffening, and scarring of tissue within the lungs). This medicine slows down the formation of scar tissue in the lungs.
Pirfenex Tablet has some side effects like nausea, vomiting, diarrhoea, heartburn, stomach pain, headache, dizziness, drowsiness, etc. Consult your doctor if these symptoms bother you for a long time or become severe. Do not take this medicine if you are allergic to it.
Pirfenex Tablet should be taken with food in the dose and duration prescribed by your doctor. Do not take more than the recommended dose. Take it every day at the same time for the ease of remembering and better results. Do not discontinue this medicine without consulting your doctor as it may worsen your condition.
Pirfenex Tablet may not be suitable for all people. It is not recommended for use in children below 18 years of age as the safety and efficacy data are not available. Inform your doctor if you have any other health conditions or taking any other medications. Consult your doctor if you are pregnant or are breastfeeding before taking this medicine.
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Substitutes
List of substitutes for Pirfenex Tablet
Pirfetab 200 mg Tablet
Zydus Cadila
Side effects
Major & minor side effects for Pirfenex Tablet
Sunburn
Nausea and vomiting
Stomach pain
Diarrhoea
Dizziness
Headache
Weight loss
Difficulty falling asleep
Skin rash
Loss of appetite
Drowsiness
Uses of Pirfenex Tablet
What is it prescribed for?
Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a progressive lung condition that causes scarring of the lungs, making it difficult to breathe. Pirfenex Tablet is used in the treatment of Idiopathic pulmonary fibrosis.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The amount of time required for Pirfenex Tablet to show its action is not clinically established.How long do the effects of this medicine last?
The amount of time for which Pirfenex Tablet remains active in your body is not clinically established.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
No habit-forming tendencies were reported for Pirfenex Tablet.Can this medicine be taken during pregnancy?
Pirfenex Tablet is not recommended for use during pregnancy unless necessary. Hence, consult your doctor if you are pregnant.Can this medicine be taken while breast-feeding?
It is unknown if Pirfenex Tablet passes into the breastmilk. Hence it is not recommended for use while breastfeeding unless necessary.
Allergy
Avoid taking Pirfenex Tablet if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Severe Liver/Kidney Impairment
Pirfenex Tablet is not recommended for use if you have severe liver/kidney impairment due to the risk of worsening your condition.
Warnings for special population
Pregnancy
Pirfenex Tablet is not recommended for use during pregnancy unless necessary. Hence, consult your doctor if you are pregnant.
Breast-feeding
It is unknown if Pirfenex Tablet passes into the breastmilk. Hence it is not recommended for use while breastfeeding unless necessary.
General warnings
Smoking
Avoid smoking during treatment with Pirfenex Tablet as it may alter the desired effects of this medicine.
Use in children
Pirfenex Tablet is not recommended for use in children less than 18 years of age.
Severe sunburn
Avoid direct exposure to sunlight as Pirfenex Tablet makes your skin sensitive to sunlight and heat. Thus it may cause severe sunburn in some people. Use sunscreen and wear protective clothing when going out in the sun.
Angioedema
Pirfenex Tablet should be used with caution as it may cause angioedema (a condition of swelling of the area beneath the skin). It is not recommended for use if you have a history of angioedema as it may worsen your condition.
Driving vehicles and operating machines
Pirfenex Tablet may cause dizziness and drowsiness in some people. Avoid activities that require high mental alertness like driving vehicles and operating heavy machines if you experience any of these symptoms.
Missed Dose
Take the missed dose of Pirfenex Tablet as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose
Never take more than the recommended dose of Pirfenex Tablet. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Ciprofloxacin
Teriflunomide
Amiodarone
Rifampicin
Disease interactions
Liver impairment
Use Pirfenex Tablet with extreme caution if you have mild to moderate liver problems, as it may further worsen your condition. Your doctor may suggest tests to closely monitor your liver function, if necessary, during treatment with this medicine.
Kidney impairment
Use Pirfenex Tablet with extreme caution if you have mild to moderate kidney problems, as it may further worsen your condition. Your doctor may suggest tests to closely monitor your kidney function, if necessary, during treatment with this medicine.
Food interactions
Avoid consumption of grapefruit or grapefruit juice while taking Pirfenex Tablet as it may increase the absorption of this medicine in your body and lead to side effects.
Lab interactions
Information not available.
Take Pirfenex Tablet preferably with food to avoid the risk of side effects such as dizziness, diarrhoea, nausea, vomiting, and upset stomach.
Do not take in larger amounts than prescribed. Consult your doctor if you experience any undesirable effects that persist or worsen.
Avoid consuming grapefruit juice along with this medicine as it may increase the risk of side effects.
Avoid driving vehicles or operating machines after taking this medicine as it may cause dizziness and drowsiness.
This medicine may make your skin more sensitive to sunlight. Use sunscreen and wear protective clothing when going out in the sun.
Miscelleneous
How it works
Pirfenex Tablet works by blocking the action of certain substances that are involved in the scarring of tissue in the lungs. Thus it slows down the progression of idiopathic pulmonary fibrosis.
Legal Status
Classification
Category
Transforming Growth Factor Inhibitors
Schedule
Schedule H
Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 3 December 2021].
CiplaMed. 2021. PIRFENEX Tablets. [online] Available at: < [Accessed 3 December 2021].
Medicines.org.uk. 2021. Esbriet 267 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 3 December 2021].
Drugs, H., 2021. Pirfenidone: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 3 December 2021].
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Information on this page was last updated on 4 Jan 2022
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.