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Peblin-M 75 Capsule
Manufactured byMOVA PHARMACEUTICALS PVT LTD
ContainsPregabalin (75 mg) + Methylcobalamin (500 mcg)
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Description
Peblin-M 75 Capsule is a combination of Pregabalin and Methylcobalamin. It is used for the treatment of neuropathic pain (pain due to damage or injury to the nerves) in adults. This medicine works by regulating the calcium channel activity in your nerve cells, protects and regenerates injured nerve fibres.
Peblin-M 75 Capsule causes headache, dizziness and drowsiness. This medicine may also cause increased appetite and weight gain. If you experience any unusual behavioural changes such as depression and suicidal thoughts, inform your doctor immediately.
Peblin-M 75 Capsule can be taken with or without food, preferably at bedtime. Take it at the same time every day for better results. You should never take more than the prescribed dose as it is habit-forming medicine and may lead to undesired effects.
Even if you feel better, complete the entire course of this medicine. Abrupt discontinuation can worsen your condition and may lead to withdrawal symptoms like headache, mood swings, irritation, etc.
Peblin-M 75 Capsule is not recommended if you have any problems related to kidney, liver, heart disease and alcohol addiction. It is not advisable for use in children and adolescents less than 18 years of age. Inform your doctor if you are pregnant or are breastfeeding.
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Substitutes
List of substitutes for Peblin-M 75 Capsule
Side effects
Major & minor side effects for Peblin-M 75 Capsule
Headache
Dizziness
Drowsiness
Confusion
Increased appetite
Weight gain
Irritability
Dry mouth
Constipation
Flatulence
Uses of Peblin-M 75 Capsule
What is it prescribed for?
Neuropathic pain
Neuropathic pain is pain caused by damage or injury to your nerves. It can occur due to a variety of diseases such as diabetes (increased blood sugar level) or shingles (viral infection that leads to painful, blistering skin rash). The pain could be sharp, shooting, throbbing, may lead to tingling and numbness.
Peblin-M 75 Capsule reduces the pain and also helps in the formation of myelin, a chemical that protects nerve fibres and regenerates injured nerve cells.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The amount of time required for Peblin-M 75 Capsule to show its effects is not clinically known.How long do the effects of this medicine last?
The amount of time for which Peblin-M 75 Capsule remains effective is not clinically known.Is it safe to consume alcohol while taking this medicine?
It is recommended that you should avoid or limit the consumption of alcohol if you have taken Peblin-M 75 Capsule as it may increase the risk of dizziness, drowsiness and difficulty in concentrating.Is this a habit forming medicine?
This medicine has a low abuse potential with limited physical and psychological dependence.Can this medicine be taken during pregnancy?
It is recommended that you consult your doctor before taking Peblin-M 75 Capsule if you are pregnant. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.Can this medicine be taken while breast-feeding?
Peblin-M 75 Capsule is not recommended for use if you are breastfeeding. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
Allergy
It is recommended to avoid Peblin-M 75 Capsule if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.
Warnings for special population
Pregnancy
It is recommended that you consult your doctor before taking Peblin-M 75 Capsule if you are pregnant. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
Breast-feeding
Peblin-M 75 Capsule is not recommended for use if you are breastfeeding. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings
Kidney disease and dialysis
Peblin-M 75 Capsule should be used with extreme caution if you have impaired kidney function. Monitor your kidney function regularly while you are on treatment with this medicine.
Suicidal tendencies
You should use Peblin-M 75 Capsule with caution because it might trigger suicidal thoughts, especially if you have a history of such tendencies. If you experience any changes in your mood or behaviour, inform your doctor immediately.
Driving or operating machinery
Peblin-M 75 Capsule may cause drowsiness or dizziness. It is recommended that you do not perform any activities such as driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.
Drug Withdrawal
Abrupt discontinuation of Peblin-M 75 Capsule may increase the risk of adverse effects, especially if you have been using a high dose for a long duration. It may lead to certain side effects such as irritability, mood swings, depression, etc. Do not stop the use of this medicine without consulting your doctor.
Oedema
Oedema is a condition of fluid retention in your body. You should use Peblin-M 75 Capsule with caution if you have the swelling disorder as it may increase fluid retention in your body. Your doctor may adjust an appropriate dose or prescribe an alternative based on your clinical condition.
Heart disease
Use Peblin-M 75 Capsule with caution if you have heart disease. This medicine may cause abnormal heart rate which could result in blockage and associated complications. Close monitoring of heart function and vital signs are required. Your doctor may adjust an appropriate dose or prescribe an alternative based on your clinical condition.
Potential for abuse
Peblin-M 75 Capsule may cause dependency, especially if you are an alcoholic or who have used other recreational drugs in your past. Report the past use of alcohol or other drugs to your doctor before receiving this medicine. Your doctor may prescribe a suitable alternative based on your clinical condition.
Rhabdomyolysis
Rhabdomyolysis is a rare case of muscle breakdown disorder that affect kidneys. Avoid using Peblin-M 75 Capsule if you have this condition. You should report any instance of muscle pain, weakness, the presence of dark reddish colouration of urine, etc. to your doctor on priority. Close monitoring of your clinical condition is necessary. Your doctor may adjust an appropriate dose or prescribe an alternative based on your clinical condition.
Use in elderly
Peblin-M 75 Capsule should be used with caution in elderly patients due to the increased risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on your clinical condition.
Gastrointestinal surgery
Peblin-M 75 Capsule should be used with caution if you have or had recent surgery of the stomach or intestines due to the increased risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on your clinical condition.
Use in children
Peblin-M 75 Capsule is not recommended for use in children and adolescents less than 18 years of age because the safety and effectiveness of its use are not clinically established.
Missed Dose
If you missed a dose of Peblin-M 75 Capsule at a given time, then take it as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose
Never take more than the prescribed dose of Peblin-M 75 Capsule. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
It is recommended that you should avoid or limit the consumption of alcohol if you have taken Peblin-M 75 Capsule as it may increase the risk of dizziness, drowsiness and difficulty in concentrating.
Interaction with Medicine
Chloramphenicol
Lorazepam
Buprenorphine
Oxycodone
Propoxyphene
Hypoglycemic agents
ACE inhibitors
Disease interactions
Angioedema
Angioedema is painless swelling under your skin due to allergy. It is recommended that you should not take Peblin-M 75 Capsule if you have angioedema as it may worsen your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Peblin-M 75 Capsule as instructed by your doctor.
Do not take in larger or smaller amounts than advised/prescribed.
Consult your doctor if you experience any undesirable effects.
Ensure that the course of treatment is completed.
Do not stop the use of this medicine without consulting your doctor.
Do not stop the use of this medicine abruptly because it may cause severe withdrawal symptoms.
Miscelleneous
How it works
Peblin-M 75 Capsule is a combination of Pregabalin and Methylcobalamin. Pregabalin works by regulating calcium channel activity in nerve cells to reduce pain. Methylcobalamin is a vitamin B form that aids in the formation of myelin (a chemical that protects nerve fibres and regenerates injured nerve cells).
Legal Status
Classification
Category
Gamma-aminobutyric acid analogs, Vitamins
Schedule
Schedule H
Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 25 August 2021].
Dailymed.nlm.nih.gov. 2021. DailyMed - PREGABALIN capsule. [online] Available at: < [Accessed 25 August 2021].
Drugs, H., 2021. Pregabalin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 25 August 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Methyl vitamin B12. [online] Available at: < [Accessed 25 August 2021].
Ods.od.nih.gov. 2021. Office of Dietary Supplements - Vitamin B12. [online] Available at: < [Accessed 25 August 2021].
Medicines.org.uk. 2021. Alzain 75 mg Capsules, Hard - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 25 August 2021].
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Information on this page was last updated on 27 Aug 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.