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Onitraz 100 MG Capsule

Manufactured byKlm Pharmaceuticals
ContainsItraconazole
CURRENTLY UNAVAILABLE

Description

Onitraz 100 MG Capsule is an antifungal medicine used in the treatment of fungal infections in various parts of your body like the lungs, nails, mouth, throat, etc. It works by preventing the growth of fungi that are responsible for causing the infections. Onitraz 100 MG Capsule may show some side effects such as diarrhoea, nausea, stomach pain, bloating, dizziness, fatigue, headache, menstrual problems, etc. If you notice any allergic reactions like a skin rash, tingling sensation in your arms and legs, difficulty in breathing, or swelling of your face, lips, tongue, or neck, seek emergency medical attention. Onitraz 100 MG Capsule is recommended to be taken with food and plenty of water to ensure maximum absorption. Take it exactly as prescribed by your doctor. Even if your symptoms are relieved after a few days, do not stop taking this medication without consulting your doctor first. Sudden discontinuation may cause your infection to reappear and become resistant to further treatment. Consult your doctor if you do not notice any changes in your condition. Onitraz 100 MG Capsule is not recommended if you have a history of heart failure. Inform your doctor if you have any other medical conditions, or if you are taking any medications. Avoid taking this medicine if you are pregnant, especially in the first trimester as it may cause harm to your foetus. If you are breastfeeding, take this medicine only after your doctor's recommendation.
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Substitutes

List of substitutes for Onitraz 100 MG Capsule

Canditral 100 MG Capsule
Glenmark Pharmaceuticals Ltd.
Intranil 100 MG Capsule
Wockhardt Ltd.
Sporaz 100 mg Capsule
Emcure Pharmaceuticals Ltd.
Itragen 100 Capsule
Macleods Pharmaceuticals Pvt. Ltd.
ITRALASE 100 CAPSULE
Cipla Ltd.

Side effects

Major & minor side effects for Onitraz 100 MG Capsule

Diarrhoea

Fever

Heartburn

Gas or bloating

Sore or bleeding gums

Decreased sexual urge

Constipation

Dizziness

Nervousness

Blurred vision

Frequent urination

Ringing in ears

Nausea

Stomach pain

Problem in menstrual period

Headache

Fatigue

Uses of Onitraz 100 MG Capsule

What is it prescribed for?

Blastomycosis

Blastomycosis is a fungal infection that can affect your lungs and also other parts of the body such as skin, bones, and joints. This condition is mostly asymptomatic (does not show symptoms) in the early stages, and when the infection becomes severe, it shows symptoms like night sweats, fever, cough, weight loss, chest pain, tiredness, etc. Onitraz 100 MG Capsule slows down the growth of this fungus and prevents it from spreading, thus it helps in treating the condition.

Histoplasmosis

Histoplasmosis is a fungal infection that primarily affects your lungs. This condition may resolve on its own, but you will need treatment if the condition is severe. Onitraz 100 MG Capsule is used to treat this condition by preventing fungal growth.

Invasive Aspergillosis

Invasive Aspergillosis is a fungal infection that mainly affects the lungs and spreads to other body parts like the brain, heart, kidney and skin. This infection may become life-threatening if you have a compromised immune system (immune system become weak due to certain medicines or diseases) or other underlying conditions. Onitraz 100 MG Capsule slows down the spread of this fungus and thus helps in treating the condition.

Onychomycosis

Onychomycosis is a fungal infection in the fingernail and toenail. It is characterized by nail discolouration, ragged or crumbly nails, etc. Onitraz 100 MG Capsule helps prevent the spread of infection by reducing the growth of fungi.

Vulvovaginal Candidiasis

Vulvovaginal candidiasis is a fungal infection in the vagina that causes itching and white discharge. Onitraz 100 MG Capsule helps in treating its symptoms and reduces the growth of the fungus.

Pityriasis versicolor

Pityriasis Versicolor is a fungal infection that affects the skin and leads to small flaky, discoloured patches on your chest and back. Onitraz 100 MG Capsule works by killing fungus and preventing their growth. This relieves the different symptoms caused by the infection and speeds up the healing process.

Dermatophytoses

Dermatophytoses is the infection caused by a fungus that affects your skin, nails or scalp. Onitraz 100 MG Capsule stops the growth of fungus and helps in treating its symptoms like itchiness and rashes.

Oral candidiasis

Oral candidiasis is a fungal infection that is seen in the mouth. This condition is characterised by white lesions on the tongue and inner cheeks. Onitraz 100 MG Capsule reduces these white lesions by preventing the growth of fungus.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The time taken by Onitraz 100 MG Capsule to show its effect is not clinically known. However, you need to take this medicine for a few months to see improvement in your infection.

  • How long do the effects of this medicine last?

    The time for which Onitraz 100 MG Capsule remains in your body is around 6 days.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit-forming tendencies were reported for Onitraz 100 MG Capsule.

  • Can this medicine be taken during pregnancy?

    Onitraz 100 MG Capsule is not recommended for use in pregnancy, especially during the first trimester. Consult your doctor if you are pregnant, or are planning a pregnancy.

  • Can this medicine be taken while breast-feeding?

    Onitraz 100 MG Capsule may be excreted in breast milk in a trace amount. Kindly consult your doctor before taking this medicine.

Allergy

Avoid taking Onitraz 100 MG Capsule if you are allergic to Itraconazole or any other components present in the medicine. Seek immediate medical attention if you have symptoms such as skin rashes, itching/swelling (especially of the face/tongue/lips/throat), shortness of breath, etc.

QT interval prolongation

Onitraz 100 MG Capsule may cause a problem in your heart rhythm called prolonged QT intervals (an electrical heartbeat disturbance), especially if you are taking it along with your heart medications. It may result in fast, rapid, and irregular heartbeats. Consult your doctor for further guidance in such conditions.

Congestive Heart Failure

Do not take Onitraz 100 MG Capsule if you have a history of pre-existing congestive heart failure (a condition in which the heart is unable to pump blood efficiently) or other severe heart conditions as prolonged therapy with itraconazole may worsen your condition.

Warnings for special population

Pregnancy

Onitraz 100 MG Capsule is not recommended for use in pregnancy, especially during the first trimester. Consult your doctor if you are pregnant, or are planning a pregnancy.

Breast-feeding

Onitraz 100 MG Capsule may be excreted in breast milk in a trace amount. Kindly consult your doctor before taking this medicine.

General warnings

Liver diseases

Onitraz 100 MG Capsule can cause moderate to severe side effects on your liver, and in a rare case, it may result in serious liver toxicity. If you have a history of liver problems, inform your doctor beforehand.

Hearing loss

Quinidine is a medicine used to treat irregular heartbeats. The use of Onitraz 100 MG Capsule along with Quinidine may result in temporary or permanent hearing loss. When the treatment is discontinued after your doctor's advice, hearing loss usually resolves, but consult your doctor if it persists.

Driving or operating a machine

Therapy with Onitraz 100 MG Capsule may cause dizziness, confusion, or disorientation in some cases. Hence, avoid activities such as driving vehicles or operating machines if you experience any of these symptoms.

Immunocompromised patients

If you have a weak or compromised immunity [e.g., in neutropenia (low level of white blood cells), AIDS (acquired immunodeficiency syndrome) or after organ transplantation], Onitraz 100 MG Capsule may not be effective enough to treat the infection. Consult your doctor for further guidance in this regard.

Neuropathy

Neuropathy is a condition where there is destruction or dysfunction of one or more nerves, resulting in numbness, muscular weakness, tingling, and pain in the affected region. If you experience these symptoms while taking Onitraz 100 MG Capsule, inform your doctor immediately. Discontinue the treatment only on your doctor’s recommendation.

Women of child bearing age

Women of childbearing age should use contraceptive precautions while taking Onitraz 100 MG Capsule. Continue the use of contraceptives until the next menstrual cycle even after stopping the treatment.

Missed Dose

If you forget to take a dose of Onitraz 100 MG Capsule, make sure that you take it as soon as you remember. However, do not take two doses together to make up for a forgotten dose.

Overdose

Never take more than the prescribed dose. If you suspect that you might have taken an overdose of Onitraz 100 MG Capsule, seek immediate medical guidance.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Alprazolam

Erythromycin

Warfarin

Atorvastatin

Disease interactions

Liver Disease

Onitraz 100 MG Capsule should be taken with caution if you have liver problems. This medicine is mostly metabolized in the liver, so you will be advised to monitor your liver function regularly.

Achlorhydria

Achlorhydria is a disorder in which your stomach fails to produce hydrochloric acid, a component of the stomach acid that is required for digestion. The absorption of Onitraz 100 MG Capsule decreases when stomach acid is decreased. Take this medicine with caution if you are diagnosed with such conditions.

Food interactions

Take Onitraz 100 MG Capsule with food as it helps to increase absorption from the stomach thereby giving better efficacy.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Onitraz 100 MG Capsule should be taken orally with food exactly as prescribed by your doctor. Do not open, chew, or crush the capsule. Do not exceed the recommended dose. Take the medication at the same time every day. Antacid delays the absorption of this medicine hence, do not take antacids (stomach acid-reducing medicines) within two hours after taking Onitraz 100 MG Capsule. If you notice any side effects, report them to your doctor as soon as possible. Your doctor may advise for some liver function tests before starting the treatment with Onitraz 100 MG Capsule. If you observe any of the following symptoms like yellowing of the eyes or skin, black urine, or stomach discomfort, inform your doctor.

Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works

Onitraz 100 MG Capsule works by stopping a chemical known as ergosterol, which is responsible for the formation of fungal cell membrane. Thus, by stopping this mechanism this medicine stops the growth and spread of fungal infection.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Azole antifungals

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - ITRACONAZOLE- itraconazole capsules capsule. [online] Available at: < [Accessed 1 March 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1e243ffb-31be-39a7-4946-83ce7b839e0a>

Medicines.org.uk. 2021. Itraconazole 100 mg Capsules - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 1 March 2021].

https://www.medicines.org.uk/emc/medicine/32181>

Drugs, H., 2021. Itraconazole: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 1 March 2021].

https://medlineplus.gov/druginfo/meds/a692049.html>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 1 March 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020083s040s041s044lbl.pdf>

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Information on this page was last updated on 29 Aug 2021

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