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Description
Natclovir 500 mg Injection is an antiviral medicine used for the prevention of Cytomegalovirus (CMV) infection which may occur after organ transplantation and in patients with acquired immunodeficiency syndrome (AIDS). It is also used to treat CMV eye infection in patients with acquired immunodeficiency syndrome (AIDS). This medicine should be used with caution in patients with a known history of seizure disorders due to the increased risk of recurrent seizures.
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Substitutes
List of substitutes for Natclovir 500 mg Injection
Cymevene 500 mg Injection
Roche India
Cytogan 500 mg Injection
Abbott Healthcare Pvt. Ltd.
Ganguard 500 mg Injection
Ranbaxy Laboratories Ltd.
Side effects
Major & minor side effects for Natclovir 500 mg Injection
Chills
Headache
Shortness of breath
Diarrhea
Mood changes
Pain at the injection site
Unsual tiredness or weakness
Seizures
Swelling of legs
Skin rash
Decreased urine output
Uses of Natclovir 500 mg Injection
What is it prescribed for?
Cytomegalovirus Retinitis (CMV)
This medicine is used for the treatment of Cytomegalovirus Retinitis (a viral eye infection of the retina caused due Cytomegalovirus which may result in blindness) in patients with acquired immunodeficiency syndrome (AIDS).
Cytomegalovirus Prophylaxis
This medicine is used for the prevention of Cytomegalovirus infection in patients who have undergone organ transplantation and are at risk of CMV disease.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The amount of time required for this medicine to show its effect is not clinically established.How long do the effects of this medicine last?
The time until which this medicine remains active in the body is not clinically established.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
No habit forming tendency has been reportedCan this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women except in life-threatening conditions. Discuss all the risks and benefits with your doctor before receiving this medicine.Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition. Discuss all the risks and benefits with your doctor before receiving this medicine.
Allergy
This medicine is not recommended for use in patients with a known allergy to ganciclovir, any other medicine of the same class, or any other inactive ingredients present along with the formulation.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women except in life-threatening conditions. Discuss all the risks and benefits with your doctor before receiving this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition. Discuss all the risks and benefits with your doctor before receiving this medicine.
General warnings
Hematologic toxicity
This medicine should be used with caution in patients with a known history of blood disorders due to the increased risk of worsening of the patient's condition. Close monitoring of blood cell counts is necessary while receiving treatment with this medicine. Replacement with a suitable alternative may be required based on the clinical condition of the patient.
Kidney dysfunction
This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of severe side effects. Appropriate dose adjustments may be necessary based on the clinical condition of the patient.
Impairment of fertility
This medicine should be used with caution due to the increased risk of impairment of fertility in both men and women. Replacement with a suitable alternative may be required based on the clinical condition of the patient. Do not stop the use of any medicine without consulting your doctor.
Driving or operating machinery
This medicine may cause drowsiness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any drowsiness during or immediately after treatment with this medicine.
Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.
Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Clozapine
Infliximab
Zidovudine
Didanosine
Disease interactions
Bone marrow suppression
This medicine should be used with extreme caution in patients with a known history of blood disorders and bone marrow suppression due to the increased risk of worsening of the patient's condition. You may require a dose adjustment and more frequent complete blood count monitoring to safely use this medicine. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Renal Dysfunction
This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of severe adverse effects. The kidney function should be assessed before initiating the treatment. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous
How it works
This medicine works by blocking the growth and reproduction of cytomegalovirus. This helps in preventing the spread of the disease.
Legal Status
Classification
Category
Purine nucleosides
Schedule
Schedule H
Ganciclovir - DrugBank [Internet]. Drugbank.ca. 2017 [cited 28 August 2017]. Available from:
DailyMed - Ganciclovir - ganciclovir sodium injection, powder, lyophilized, for solution [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 18 November 2019]. Available from:
Ganciclovir: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 28 August 2017]. Available from:
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Information on this page was last updated on 21 Nov 2019
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.