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Mexate 10 MG Tablet

Manufactured byZydus Cadila
ContainsMethotrexate
CURRENTLY UNAVAILABLE

Description

Mexate 10 MG Tablet is a medicine used to treat rheumatoid arthritis (when the immune system attacks the joints on both sides of the body, causing pain and swelling), psoriasis (a skin condition causing rash, and itchy/scaly patches on the skin), and some types of cancers such as choriocarcinoma (uterus cancer), acute lymphoblastic leukaemia (a type of blood cancer), lymphoma (cancer that starts in the cells that are part of the body's immune system), etc. This medicine works by suppressing the activity of the immune system and helps reduce pain and swelling. It also slows the growth of cancer cells. Mexate 10 MG Tablet shows common side effects such as stomach upset, nausea, fever, chills, hair loss, headache, decreased appetite, and low blood cell counts. If these side effects persist or worsen, consult your doctor for further assistance. Avoid driving vehicles or operating heavy machines while taking this medication as it can cause dizziness or drowsiness. Mexate 10 MG Tablet can be taken with or without food. Do not crush, break, or chew the tablet. Swallow as a whole with a glass of water. Follow all the instructions given by your doctor about the dose and duration of treatment. Avoid consumption of alcohol while taking this medicine due to the increased risk of undesired effects. Do not discontinue the medicine without consulting your doctor. Mexate 10 MG Tablet is not recommended if you are allergic to it. It is not recommended if you have liver conditions, immunodeficiency syndromes (weak immune system), drinking habits, or a bone marrow condition (low platelets and white/red blood cells). It should be used with caution if you have stomatitis (swelling and sores inside the mouth), kidney conditions, ulcers, or fluid accumulation in the lungs. Your doctor may suggest tests to monitor complete blood cell count, liver function, and kidney function while you are taking this medicine. Mexate 10 MG Tablet is unsafe for use during pregnancy as it has been reported to cause harm to the developing foetus. Use effective contraceptives to avoid getting pregnant while you are taking this medicine. Mexate 10 MG Tablet can pass into breast milk. Hence it is not recommended for use while breastfeeding.
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Substitutes

List of substitutes for Mexate 10 MG Tablet

Auratrex 10 MG Tablet
Abbott Healthcare Pvt. Ltd.
Folitrax 10 MG Tablet
Ipca Laboratories Pvt. Ltd.
Imutrex 10 MG Tablet
Cipla Ltd.
Oncotrex 10 MG Tablet
Sun Pharma Laboratories Ltd.
Ramex 10 MG Tablet
Ranbaxy Laboratories Ltd.

Side effects

Major & minor side effects for Mexate 10 MG Tablet

Diarrhoea

Joint pain

Stomach pain

Swelling of feet or lower legs

Dizziness

Fever or chills

Bleeding gums

Blurred vision

Hair loss

Loss of appetite

Nausea or Vomiting

Pale skin

Skin rash

Headache

Drowsiness

Tiredness

Uses of Mexate 10 MG Tablet

What is it prescribed for?

Choriocarcinoma

Choriocarcinoma is fast-growing cancer that occurs in a woman's uterus. Mexate 10 MG Tablet is used in the treatment of Choriocarcinoma.

Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disorder that affects the small joints in the body causing pain and swelling. Mexate 10 MG Tablet is used to treat this condition along with other medicines and physical therapy.

Psoriasis

Psoriasis is an autoimmune skin condition characterised by red inflamed skin, often covered by scales. Mexate 10 MG Tablet is used to treat this condition.

Acute lymphoblastic Leukaemia (ALL) and Lymphoma

Mexate 10 MG Tablet is used in the treatment of certain cancers such as acute lymphoblastic leukaemia (a type of blood cancer), and lymphoma (cancer that starts in the cells that are part of the body's immune system). It helps to inhibit the growth of cancer cells.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The time taken for Mexate 10 MG Tablet to show its effect is not known.

  • How long do the effects of this medicine last?

    The amount of time for which Mexate 10 MG Tablet remains active in the body is not clinically established.

  • Is it safe to consume alcohol while taking this medicine?

    Avoid consumption of alcohol while you are taking Mexate 10 MG Tablet, as it may increase the risk of liver problems.

  • Is this a habit forming medicine?

    No habit-forming tendencies were reported for Mexate 10 MG Tablet.

  • Can this medicine be taken during pregnancy?

    Mexate 10 MG Tablet is unsafe for use during pregnancy as it can harm the developing foetus. Hence consult your doctor if you are pregnant.

  • Can this medicine be taken while breast-feeding?

    Mexate 10 MG Tablet may pass into the breast milk and cause serious side effects in your baby. Hence consult your doctor if you are breastfeeding.

Allergy

Avoid taking Mexate 10 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Liver disease

Mexate 10 MG Tablet is not recommended for use if you have liver conditions due to the increased risk of liver toxicity.

Blood disorder

Mexate 10 MG Tablet is not recommended for use if you have bone marrow conditions that may cause low blood cell count (red, white, or clot-forming blood cells). The use of this medicine may further worsen your condition.

Immunodeficiency syndromes

Mexate 10 MG Tablet is not recommended for use if you have an Immunodeficiency condition (weak immune system), as it can make you prone to infections.

Alcohol consumption

Mexate 10 MG Tablet is not recommended for use in case of alcoholism (addiction to alcohol) due to the increased risk of undesired effects.

Warnings for special population

Pregnancy

Mexate 10 MG Tablet is unsafe for use during pregnancy as it can harm the developing foetus. Hence consult your doctor if you are pregnant.

Breast-feeding

Mexate 10 MG Tablet may pass into the breast milk and cause serious side effects in your baby. Hence consult your doctor if you are breastfeeding.

General warnings

Driving vehicles or operating machines

Mexate 10 MG Tablet may cause blurred vision, dizziness, or confusion. Hence do not perform activities that require mental alertness, such as driving vehicles or operating machines, if you experience any of these symptoms.

Fluid accumulation in the lungs

Mexate 10 MG Tablet should be used with caution if you have fluid accumulation in your lungs. Your doctor may suggest a chest X-ray during long-term treatment with this medicine.

Kidney conditions

Mexate 10 MG Tablet should be used with caution if you have kidney problems as it may worsen your condition.

Immunization

Mexate 10 MG Tablet works by suppressing the activity of the immune system. Hence avoid getting vaccinated while you are taking this medicine as it may make the vaccine ineffective.

Missed Dose

Do not miss the dose of Mexate 10 MG Tablet. Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Do not take more than the recommended dose of Mexate 10 MG Tablet. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol while you are taking Mexate 10 MG Tablet, as it may increase the risk of liver problems.

Interaction with Medicine

Atorvastatin

NSAIDs

Omeprazole

Tetracycline

Theophylline

Disease interactions

Stomatitis

Mexate 10 MG Tablet should be used with caution if you have stomatitis (swelling and sores inside the mouth) as it can worsen your condition.

Food interactions

The desired effect of Mexate 10 MG Tablet may be altered if it is taken along with caffeine-containing foods and products. It is advised to limit the intake of such products while taking this medicine.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Mexate 10 MG Tablet can be taken with or without food. Do not break, chew, or crush the tablet. Swallow the tablet as a whole with a sufficient amount of water. Avoid taking more or less than the recommended dose. Take it at the same time every day for ease of remembering. Avoid consumption of alcohol while taking this medicine, as it may increase the risk of liver problems. Do not discontinue the tablet without consulting your doctor, as your condition may become worse. Your doctor may suggest tests to monitor your blood cell count while you are taking this medicine. Mexate 10 MG Tablet may suppress the immune activity and increase the risk of infections. Hence avoid contact with people who have infections that may spread to others. Mexate 10 MG Tablet may make your skin sensitive to sunlight. Hence avoid excessive sun exposure and wear protective clothing while stepping out in the sun.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works

Mexate 10 MG Tablet works by suppressing the activity of the immune system and helps reduce pain and swelling. It also slows the growth of cancer cells.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Other immunosuppressant, Antimetabolites, Antirheumatics, Antipsoriatics

Schedule

Schedule H

Drugs, H., 2021. Methotrexate: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 19 February 2021].

https://medlineplus.gov/druginfo/meds/a682019.html

Accessdata.fda.gov. 2021. [online] Available at: [Accessed 19 February 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/008085s066lbl.pdf

nhs.uk. 2022. Methotrexate – an immunosuppressant used to treat inflammatory conditions. [online] Available at: [Accessed 5 July 2022].

https://www.nhs.uk/medicines/methotrexate/#:~:text=Taking%20methotrexate%20tablets&text=You%20can%20take%20your%20tablets,to%20make%20up%20your%20dose.

Hannoodee, M. and Mittal, M., 2022. Methotrexate. [online] Ncbi.nlm.nih.gov. Available at: [Accessed 5 July 2022].

https://www.ncbi.nlm.nih.gov/books/NBK556114/

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Information on this page was last updated on 19 Aug 2022

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.