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Mesacol Enema

Manufactured bySun Pharma Laboratories Ltd.
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Description

Mesacol Enema is used for the treatment of ulcerative proctitis (a mild form of ulcerative colitis, involving only the rectum), and proctosigmoiditis (a mild form of ulcerative colitis, involving the rectum and sigmoid colon) characterized by rectal bleeding, bloody diarrhea, redness, and ulcerations of the lining of the rectum.

Substitutes

List of substitutes for Mesacol Enema

Side effects

Major & minor side effects for Mesacol Enema

Rectal pain

Rectal Irritation

Dizziness

Skin rash

Flatulence (Passing of gas)

Uses of Mesacol Enema

What is it prescribed for?

Ulcerative proctitis and proctosigmoiditis

This medicine is used for the treatment of ulcerative proctitis (a mild form of ulcerative colitis, involving only the rectum), and proctosigmoiditis (a mild form of ulcerative colitis, involving the rectum and sigmoid colon) characterized by rectal bleeding, bloody diarrhea, redness, and ulcerations of the lining of the rectum.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The amount of time required by this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?

    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?

    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to mesalazine or any other components present along with the formulation.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

General warnings

Use of nephrotoxic medicines

The use of nephrotoxic medicines along with this medicine may increase the risk of kidney damage. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition. It is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine to avoid such interactions.

Use of nonsteroidal anti-inflammatory drug (NSAIDs)

The use of NSAIDs along with this medicine may increase the risk of kidney impairment. Replacement with a suitable alternative should be considered under your doctor's supervision. It is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine to avoid such interactions.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Use in children

This medicine is not recommended for use in children under 18 years of age since safety and efficacy are not clinically established.

Missed Dose

Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

Kidney impairment

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Food interactions

Information not available.

Lab interactions

Information not available.
Use this medicine as advised by your doctor. Do not use in larger amounts than advised. Consult the doctor if you experience any undesirable side effects. Follow all the instructions given in the patient information leaflet.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works

This medicine reduces and prevents the worsening of symptoms of ulcerative proctitis and proctosigmoiditis by blocking the production of certain natural substances in the colon and rectum.

Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Anti-inflammatory agents, Rectal preparations

Schedule

Schedule H

Mesalamine Rectal: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 11 June 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a614021.html

Internet]. Medsafe.govt.nz. 2020 [cited 11 June 2020]. Available from:

https://www.medsafe.govt.nz/Consumers/cmi/p/pentasa-enema.pdf

[Internet]. Rad-ar.or.jp. 2020 [cited 3 July 2020]. Available from:

https://www.rad-ar.or.jp/siori/english/kekka.cgi?n=1361

Related Questions

Question:
May I please know if there are any reactions of zossert 100mg with Mesacol 1200. I was under treatme...more
Answer from Dr. Nishant Kumar Jaiswal
Both may be taken together.
Question:
May I please know if there are any reactions of zossert 100mg along with Mesacol 1200. I am currentl...more
Answer from Dr. Santosh D Dasarwar
The above indicated medication on a longer consumption can cause GIT Issue. It n...more
Question:
I accidently took two pills of mesacol OD after dinner. I took one pill just at dinner table and too...more
Answer from Dr. Gnanendra DM
Nothing will happen mesacol od u can take upto 4 tab per day ok no need to worry
Question:
Can I use biotin and omega 3 with mesacol od I m suffering from ulcerative colitis and I will used m...more
Answer from Dr. Sushma Shah
Hello, till u relived or  take intermittently.ok
Question:
How close are we towards the cure for ulcerative colitis. I want to stop taking Mesacol . Let me kno...more
Answer from Dr. Jatin Agrawal
Hi Better if you consult then we can discuss regarding this topic. Not possible ...more
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Information on this page was last updated on 3 Jul 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.