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Megaclox-DT Tablet
Manufactured byCIPLA LTD
ContainsAmpicillin (125 mg) + Dicloxacillin (125 mg)
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Description
Megaclox-DT Tablet is a combination medicine which may be used to treat a variety of conditions caused by bacterial infections of the skin, bone, respiratory tract, urinary tract, etc. caused by susceptible bacteria. This medicine is not recommended for treating a common cold, flu, or other viral infections since it is not effective in treating them.
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Substitutes
List of substitutes for Megaclox-DT Tablet
Side effects
Major & minor side effects for Megaclox-DT Tablet
Nausea and vomiting
Diarrhea
Skin Rash
Stomach upset
Itching
Flatulence (Passing of gas)
Dizziness
Uses of Megaclox-DT Tablet
What is it prescribed for?
Skin or soft tissue infection
This medicine may be used to treat bacterial skin and soft tissue infections characterized by symptoms such as fever with chills, redness around hair follicles, yellowish rash, and muscle pain.
Respiratory Tract Infection
This medicine may be used for the treatment of acute infections of the respiratory tract such as pharyngitis, sinusitis, bronchitis, pneumonia, etc. caused by susceptible bacteria.
Osteomyelitis (Infection of bone)
This medicine may be used for the treatment of osteomyelitis, an infection of the bones caused by bacteria. This generally occurs in the legs, arms, or spine.
Bacterial Meningitis
This medicine may be used in the treatment of meningitis, which is an inflammation of the protective membranes that surround the brain and spinal cord, caused by susceptible bacteria.
Bacterial Septicemia
This medicine may be used in the treatment of Septicemia which is an infection of the blood caused by susceptible strains of bacteria.
Urinary Tract Infection
This medicine may be used in the treatment of infections of the urinary tract caused by susceptible strains of bacteria.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The effect of this medicine can be observed within 30 minutes of administration of the dose.How long do the effects of this medicine last?
The effect of this medicine lasts for an average duration of 6 hours.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
No habit-forming tendencies were reported.Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.
Allergy
This medicine is not recommended for use in patients with a known allergy to ampicillin, dicloxacillin, other antibiotics of penicillin or cephalosporin group, or any other inactive ingredients present in the formulation.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.
General warnings
Clostridium difficile-associated diarrhea
Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.
Drug-resistance
Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug-resistant.
Hypersensitivity reactions
This medicine may cause serious and occasionally fatal hypersensitivity reactions including anaphylactic shock in some patients. This risk is especially high in patients with a history of sensitivity to multiple allergens. If an anaphylactic reaction occurs, the treatment should be discontinued immediately and appropriate corrective measures should be undertaken.
Driving or Operating machinery
Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Live cholera vaccine
Atenolol
Methotrexate
Doxycycline
Chloroquine
Ethinyl Estradiol
Warfarin
Disease interactions
Bone Marrow Depression
This medicine should be used with caution in patients with bone marrow depression due to the increased risk of worsening of the patient's condition. Close monitoring of blood counts is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Colitis
This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Cystic fibrosis
This medicine should be used with caution in patients with cystic fibrosis since the effects of this medicine may be reduced in such patients. Report any lack of improvement to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Kidney Disease
This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of adverse effects. Regular monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine at least 1 hour before or 2 hours after meals. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before completion of course.
Miscelleneous
How it works
This medicine works by interfering with certain processes that help the bacteria to form new cell walls. This helps in stopping the growth and multiplication of bacteria and eventually kills them.
Legal Status
Classification
Category
Aminopenicillins, Penicillinase resistant penicillins
Schedule
Schedule H
Dicloxacillin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 16 March 2018]. Available from:
Ampicillin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 31 August 2018]. Available from:
DailyMed- dicloxacillin sodium capsule [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 16 March 2018]. Available from:
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Information on this page was last updated on 25 Jul 2019
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.