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Meftal MR (500/2 mg) Tablet
Manufactured byBlue Cross Laboratories Ltd.
ContainsMefenamic acid (500 mg) + Tizanidine (2 mg)
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Description
Meftal MR (500/2 mg) Tablet is a short-acting combination medicine used to relieve acute musculoskeletal pain and muscle spasms associated with medical conditions such as gout, rheumatoid arthritis, osteoarthritis, sprains, etc. It is also used to relieve pain and cramps associated with menstrual cycles. This medicine is not recommended for use in children.
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Substitutes
List of substitutes for Meftal MR (500/2 mg) Tablet
Side effects
Major & minor side effects for Meftal MR (500/2 mg) Tablet
Chest pain or discomfort
Fever or chills
Nausea and vomiting
Nervousness
Painful or burning urination
Unusual tiredness
Blurred vision
Flu like symptoms
Irregular heartbeat
Itching skin
Shortness of breath
Diarrhea
Headache
Dizziness
Ringing or buzzing in the ears
Weight gain
Dry mouth
Loss of appetite
Increased blood pressure
Uses of Meftal MR (500/2 mg) Tablet
What is it prescribed for?
Muscle spasm with acute pain
This medicine is used to relieve acute musculoskeletal pain and muscle spasms associated with various medical conditions such as gout, rheumatoid arthritis, osteoarthritis, sprains, etc.
Dysmenorrhea
This medicine is used to relieve pain and cramps associated with menstrual cycles.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The effect of this medicine can be observed within 20 to 30 minutes of administration.How long do the effects of this medicine last?
The amount of time for which this medicine remains active in the body is not clinically established.Is it safe to consume alcohol while taking this medicine?
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, severe gastrointestinal bleeding, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.Is this a habit forming medicine?
No habit-forming tendencies were reported.Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
Allergy
This medicine is not recommended for use in patients with a known allergy to mefenamic acid, any other NSAIDs, tizanidine, or any other components present along with these medicines.
CYP1A2 inhibitors
This medicine is not recommended for use in patients receiving CYP1A2 inhibitors such as ciprofloxacin or fluvoxamine due to the increased risk of severe adverse effects.
Other allergic conditions
This medicine is not recommended for use in patients with allergic conditions such as asthma or urticaria since it may worsen the patient's condition.
Coronary Artery Bypass Surgery (CABG)
This medicine is not recommended for use before or after a CABG (coronary artery bypass graft) procedure since it may worsen the patient's condition.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
General warnings
Hypotension
This medicine should be used with caution in patients with a known history of hypotension or patients predisposed to hypotension due to the increased risk of hypotensive episodes. Appropriate dose adjustments and close monitoring of blood pressure may be required for such patients.
Renal impairment
This medicine should be used with caution in patients with a known history of renal impairment due to the increased risk of severe adverse effects. Close monitoring of renal function and appropriate dose adjustments may be necessary based on the clinical condition.
Liver impairment
This medicine should be used with caution in patients with a known history of liver impairment due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is recommended for such patients. Therapy may need to be discontinued based on the clinical condition.
Use with sedative medicines
This medicine should be used with caution in patients receiving sedatives since it may increase the sedative effects of such medications. Any unusual symptoms should be reported to the doctor on priority. Appropriate dose adjustments should be done under your doctor's supervision.
Drowsiness
This medicine may cause drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you suffer from drowsiness during treatment with this medicine.
Cardiovascular effects
Use of this medicine for a long duration may cause fluid retention and heart failure. This risk is especially higher in patients with a history of cardiovascular diseases. Appropriate corrective measures, frequent clinical monitoring, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Peptic ulcer
This medicine should be used with extreme caution in patients suffering from peptic ulcer disease due to the increased risk of severe gastrointestinal bleeding. Report any unusual bleeding or bruising to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Female fertility
This medicine may cause a reversible delay in ovulation. Hence, female patients with reproductive potential who desire pregnancy should discuss all the risks and benefits with the doctor before taking this medicine.
Infections
This medicine may mask the signs and symptoms of infections, making them harder to detect.
Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, severe gastrointestinal bleeding, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine
Amlodipine
Atenolol
Citalopram
Clozapine
Glimepiride
Methotrexate
Ramipril
Tacrolimus
Amiodarone
Warfarin
Furosemide
Aspirin
Ketorolac
Immune globulin (intravenous)
Disease interactions
Renal Dysfunction
This medicine should be used with caution in patients with a known history of renal dysfunction due to the increased risk of severe adverse effects. Appropriate dose adjustments may be required based on the clinical condition.
Hypotension
This medicine should be used with caution in patients with a known history of hypotension or patients predisposed to hypotension due to the increased risk of hypotensive episodes. Appropriate dose adjustments and close monitoring of blood pressure are recommended for such patients.
Liver Disease
Meftal MR (500/2 mg) Tablet should be used with caution in patients with a known history of liver diseases due to the increased risk of liver injuries. Liver function should be assessed before initiating treatment. Close monitoring of liver function may be necessary during treatment with this medicine. Therapy may need to be discontinued based on the clinical condition.
Asthma
This medicine is not recommended for use in patients with a known history of aspirin or NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.
Fluid Retention and edema
This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.
Gastro-Intestinal toxicity
This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Skin rash and peeling
This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Consumption of caffeine may increase the effects of Meftal MR (500/2 mg) Tablet. This may cause side effects such as drowsiness, dizziness, lightheadedness, fainting, irregular heartbeat, etc. Hence, you are advised to avoid the consumption of caffeine during treatment with this medicine.
Lab interactions
Diazo test for urinary bile
You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
Take this medicine as prescribed by the doctor. Carefully follow all the instructions mentioned on the label or package insert. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
Mefenamic acid works by blocking the production of certain chemicals responsible for causing pain, swelling, and fever. Tizanidine acts on the nervous system and reduces muscle spasms, allowing the muscles to relax.
Legal Status
Classification
Category
Non-steroidal anti-inflammatory agent combinations, Skeletal muscle relaxant combinations
Schedule
Schedule H
DailyMed - Mefenamic acid capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 May 2017]. Available from:
Mefenamic Acid: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 30 May 2017]. Available from:
DailyMed - Tizanidine Hydrochloride tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 August 2017]. Available from:
Tizanidine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 30 August 2017]. Available from:
[Internet]. 2017 [cited 19 September 2017]. Available from:
Related Questions
Question:
My kid is having high fever and temperature. Doctor suggest for meftal. After one also fever is not ...more
Answer from Dr. Sushma Shah
HELLO, MEFTAL IS FOR PAIN WHO SAYS IT IS FOR FEVER.
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Question:
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Not the safest medicine in pregnancy. Ask your doctor to suggest you something s...more
Question:
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Answer from Dr. Ritu Jain
If pain at 34 weeks, see your gynaec. Don't self medicate. It's would be disastr...more
Question:
My son got fever and we are under doctor care. We need an answer for a query plz.
He took dilo 650 ...more
Answer from Dr. Tangade Vishal Bhanudas
Need weight to comment.
Question:
I used to use meftal tlabet if have cramps during periods is it harmfull or will i not get pregnant ...more
Answer from Dr. Inthu
both are coming period during periods or pregnancy can have cramps so contact di...more
Information on this page was last updated on 9 Feb 2018
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.