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Lambin Lyophilised 50 mg Injection

Manufactured bySun Pharma Laboratories Ltd.
ContainsAmphotericin B (Liposomal)
CURRENTLY UNAVAILABLE

Description

Lambin Lyophilised 50 mg Injection is an antifungal medicine. It is used to treat serious and life-threatening fungal infections caused by different fungal species. This medicine works by stopping the growth of fungi. Lambin Lyophilised 50 mg Injection shows side effects like decreased potassium levels, nausea, vomiting, chills, diarrhoea, weakness, etc. Consult your doctor if any of these side effects do not resolve with time or worsen. Avoid receiving this medicine if you are allergic to it. Lambin Lyophilised 50 mg Injection will be administered in a hospital setting by a healthcare professional. Your doctor will decide the dose and duration of treatment based on the severity of the infection. Do not self administer this medicine. Lambin Lyophilised 50 mg Injection should be used with caution if you have kidney problems. Inform your doctor if you are taking any other medicines to avoid undesired effects. Inform your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Substitutes

List of substitutes for Lambin Lyophilised 50 mg Injection

Ambisome 50 mg Injection
Abbott Healthcare Pvt. Ltd.
Amphogard 50 mg Injection
Zydus Cadila
Amphotericin B (Cipla) 50 mg Injection
Cipla Ltd.
Phosome 50 mg Injection
Cipla Ltd.
Abhope Injection
Abbott Healthcare Pvt. Ltd.

Side effects

Major & minor side effects for Lambin Lyophilised 50 mg Injection

Irregular heart beat

Fever and chills

Diarrhoea

Decreased potassium levels

Anaemia

Cough

Stomach pain

Headache

Pain at injection site

Nausea and Vomiting

Chest pain

Uses of Lambin Lyophilised 50 mg Injection

What is it prescribed for?

Invasive Aspergillosis

Invasive aspergillosis is a fungal infection caused by a common mold (fungus) called Aspergillus. It occurs in individuals having a weak immune system due to cancer treatment, bone marrow transplantation (a medical treatment that replaces your bone marrow with healthy cells), organ transplant, etc. Lambin Lyophilised 50 mg Injection is used to treat invasive aspergillosis.

Candidemia

Candidemia is a condition where the fungi of the Candida species are present in the blood causing infection. Lambin Lyophilised 50 mg Injection is used to treat candidemia.

Cryptococcosis

Cryptococcosis is a fungal infection caused by Cryptococcus species that mainly affects the lungs causing severe pneumonia. If not controlled, it can affect the brain causing meningitis (swelling of the fluid and membranes surrounding the brain and spinal cord). Lambin Lyophilised 50 mg Injection is used to treat Cryptococcosis.

Febrile Neutropenia

Neutropenia is the low levels of a type of white blood cell called neutrophils. Febrile neutropenia is a condition causing high-grade fever due to low levels of neutrophils, which may increase the risk of acquiring several other infections. Lambin Lyophilised 50 mg Injection is used in the treatment of fungal infections if you have febrile neutropenia.

Leishmaniasis

Leishmaniasis is a parasite infection caused by the Leishmania species. It spreads through the bite of sand flies. This infection is characterised by an enlarged spleen and liver, fever, chills, decreased production of blood cells, weakness, weight loss, etc. Lambin Lyophilised 50 mg Injection is used in the treatment of Leishmaniasis in people with a weakened immune system.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The time Lambin Lyophilised 50 mg Injection takes to show its action is not known.

  • How long do the effects of this medicine last?

    The amount of time for which Lambin Lyophilised 50 mg Injection remains active in your body is not known.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    Lambin Lyophilised 50 mg Injection has no habit-forming tendency.

  • Can this medicine be taken during pregnancy?

    As animal studies indicate that Lambin Lyophilised 50 mg Injection does not harm the foetus, this medicine may be used during pregnancy upon your doctor's recommendation.

  • Can this medicine be taken while breast-feeding?

    It is not known if Lambin Lyophilised 50 mg Injection passes into the breastmilk. If you are breastfeeding, discuss all the risks and benefits associated with this medicine with your doctor before receiving it.

Allergy

Lambin Lyophilised 50 mg Injection is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Warnings for special population

Pregnancy

As animal studies indicate that Lambin Lyophilised 50 mg Injection does not harm the foetus, this medicine may be used during pregnancy upon your doctor's recommendation.

Breast-feeding

It is not known if Lambin Lyophilised 50 mg Injection passes into the breastmilk. If you are breastfeeding, discuss all the risks and benefits associated with this medicine with your doctor before receiving it.

General warnings

Anaphylaxis

Lambin Lyophilised 50 mg Injection may cause serious anaphylactic reactions (an allergic reaction that is serious and life-threatening if not treated immediately). An anaphylactic reaction occurs immediately after receiving any medicine you are allergic to them. Hence, your doctor will monitor you closely while administering this medicine.

Noninvasive fungal infections

Lambin Lyophilised 50 mg Injection is not recommended to treat noninvasive fungal infections in people with normal neutrophil (a type of white blood cell) counts.

Infusion reactions

Lambin Lyophilised 50 mg Injection may cause infusion reactions such as a headache, fever, chills, loss of appetite, nausea, vomiting, breathing problems, or dizziness with the first few doses. These reactions usually diminish with subsequent doses.

Missed Dose

As Lambin Lyophilised 50 mg Injection is administered in the hospital setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

As Lambin Lyophilised 50 mg Injection is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by your doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Tacrolimus

Cidofovir

Indapamide

Flucytosine

Disease interactions

Disease

Information not available.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Lambin Lyophilised 50 mg Injection should be administered in a hospital setting by a qualified healthcare professional. Carefully follow all the instructions given by your doctor. Report to your doctor about all your current medications as well as your medical conditions before receiving this medicine.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works

Lambin Lyophilised 50 mg Injection works by blocking the action of a vital component of the fungal cell membrane (protective covering). Thus it slows the growth of the fungi.

Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Polyenes, Antifungals

Schedule

Schedule H

Medicines.org.uk. 2021. [online] Available at: [Accessed 28 October 2021].

https://www.medicines.org.uk/emc/files/pil.1022.pdf

Drugs, H., 2021. Amphotericin B Liposomal Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 28 October 2021].

https://medlineplus.gov/druginfo/meds/a616018.html

2021. [online] Available at: [Accessed 28 October 2021].

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2019-PI-01848-1

Accessdata.fda.gov. 2021. [online] Available at: [Accessed 28 October 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050740s016lbl.pdf

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Information on this page was last updated on 6 Mar 2023

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.