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Gracin 40 MG Injection

Manufactured byBiochem Pharmaceutical Industries Ltd.
ContainsGentamicin
CURRENTLY UNAVAILABLE

Description

Gracin 40 MG Injection is an aminoglycoside antibiotic used for the short-term treatment of serious bacterial infections of the lungs, skin, abdomen, blood, brain, urinary tract, bones and joints. This injection kills or stops the growth of bacteria causing the infection. It is not effective against infections caused by viruses. Common side effects of Gracin 40 MG Injection are pain at the injection site, skin rash, headache, weakness, and dizziness. Do not use this medicine if you are previously allergic to it. High doses of this medicine may cause damage to your hearing, sense of balance, and kidneys. Perform your kidney function and hearing tests during treatment. Gracin 40 MG Injection is administered into your vein or muscle by a health care professional in a hospital or clinic. Once an antibiotic is started, it is always recommended to finish the entire course of treatment. This injection should only be used to treat or prevent infections that are caused by bacteria. Using an antibiotic when it is not required can make it less effective for future infections.
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Substitutes

List of substitutes for Gracin 40 MG Injection

Genka 40 MG Injection
Cadila Pharmaceuticals Ltd.
Lupigenta 40 MG Injection
Lupin Ltd.
Magenta 40 MG Injection
Wockhardt Ltd.
Ranbiotic 40 MG Injection
Ranbaxy Laboratories Ltd.
Zygenta 40 MG Injection
Zydus Cadila

Side effects

Major & minor side effects for Gracin 40 MG Injection

Stomach pain

Headache

Blurred vision

Decrease in frequency of urination

Hearing loss

Dizziness when getting up suddenly from a sitting position

Dry mouth

Fast heartbeat

Itching or rash

Increased salivation

Pain at the injection site

Uses of Gracin 40 MG Injection

What is it prescribed for?

Bacteremia

Bacteremia is the presence of bacteria in the blood. Bacteria can sometimes enter your bloodstream from dental or medical procedures, or from infections. If this condition left untreated it can lead to septicemia which is an infection of the blood caused by bacteria. Gracin 40 MG Injection is used for the treatment of bacteremia.

Intra-abdominal Infection

Intra-abdominal infection (IAI) describes several infections such as peritonitis (swelling of the peritoneum-lining of the abdominal wall), pancreatitis (swelling of the pancreas- an organ located behind the lower part of the stomach), diverticulitis (swelling of diverticula- one or more small pouches in the intestine), cholecystitis (swelling of the gallbladder-a small digestive organ that sits just under the liver), and cholangitis (swelling of the bile duct system). Gracin 40 MG Injection is used to treat infections occurring within the abdomen caused by bacteria.

Bacterial Meningitis

Bacterial meningitis is an infection of the meninges, the protective layer that surrounds the brain and spinal cord. It starts when bacteria get into your bloodstream and travel to your brain and spinal cord. Gracin 40 MG Injection is used to treat bacterial meningitis.

Bone and Joint infections

Bone and joint infections occur in the bones and joints. Osteomyelitis is an infection of the bone and septic arthritis is an infection in a joint. These infections can occur due to a bone/joint injury or through blood by which bacteria, virus, or fungi invade a bone/joint. Gracin 40 MG Injection is used for the treatment of osteomyelitis and septic arthritis caused by bacteria.

Skin and soft tissue infections

Skin and soft tissue infections occur when the bacteria invade the skin and its supporting structures. Gracin 40 MG Injection is used to treat all skin infections including abscess caused by bacteria.

Urinary tract infections

An infection in any part of your urinary system- the kidneys, bladder, ureters, or urethra is called urinary tract infections (UTIs). UTIs are the most common infections in humans and woman are at greater risk of getting this infection. UTI's can occur as complicated or uncomplicated urinary tract infections. Complicated UTI's are caused by multidrug-resistant bacteria (the bacteria may become non-responsive to more than one antibiotic) and can occur due to structural and functional abnormalities of the urinary tract. Uncomplicated urinary tract infection is an infection of the urinary tract in a healthy individual with a normal and functional urinary tract and no known reasons to develop a UTI. Gracin 40 MG Injection is used to treat complicated and uncomplicated urinary tract infections caused by bacteria.

Community-Acquired Pneumonia

Community-acquired pneumonia (CAP) refers to pneumonia (lung infection) that is acquired outside the hospital. CAP can be bacterial or viral. Gracin 40 MG Injection is used to treat CAP caused by bacteria like Mycoplasma pneumonia, Streptococcus pneumonia, Haemophilus influenzae, etc.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of gentamicin injection starts immediately after the administration. You will start to feel better in 3 to 5 days after receiving a gentamicin injection.

  • How long do the effects of this medicine last?

    The effect of gentamicin injection lasts for an average duration of 6 to 8 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit-forming tendency has been reported for Gracin 40 MG Injection.

  • Can this medicine be taken during pregnancy?

    Gracin 40 MG Injection should not be used during pregnancy unless there are no safer options. The use of gentamicin in pregnant women caused some babies to have birth defects. However, in some serious conditions, your doctor may recommend this medicine if the benefit is greater than the risk of harm to the baby.

  • Can this medicine be taken while breast-feeding?

    It is best to be cautious before using Gracin 40 MG Injection while breastfeeding because it is not known whether this medicine crosses into human milk. Hence it should only be used if the benefit is greater than the risk of harm to the baby. If used, the baby should be observed for symptoms such as diarrhoea and yeast infection.

Allergy

Avoid using Gracin 40 MG Injection if you are previously allergic to it. Some patients may get allergic reactions to this medicine. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Warnings for special population

Pregnancy

Gracin 40 MG Injection should not be used during pregnancy unless there are no safer options. The use of gentamicin in pregnant women caused some babies to have birth defects. However, in some serious conditions, your doctor may recommend this medicine if the benefit is greater than the risk of harm to the baby.

Breast-feeding

It is best to be cautious before using Gracin 40 MG Injection while breastfeeding because it is not known whether this medicine crosses into human milk. Hence it should only be used if the benefit is greater than the risk of harm to the baby. If used, the baby should be observed for symptoms such as diarrhoea and yeast infection.

General warnings

Antibiotic resistance

The entire course of treatment with Gracin 40 MG Injection should be completed, even if the condition gets better to avoid antibiotic resistance.

Hearing loss and kidney damage

High doses of Gracin 40 MG Injection may cause damage to your hearing, sense of balance, and kidneys. Perform your kidney function and hearing tests during treatment.

Missed Dose

Since Gracin 40 MG Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since Gracin 40 MG Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the chances of an overdose are very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Furosemide

Nonsteroidal anti-inflammatory drugs

Cephalosporins

Disease interactions

Disease

Information not available.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Gracin 40 MG Injection should be administered by a qualified healthcare professional in the clinical or hospital setting. Report any undesirable side effects to the doctor promptly. Gentamicin injection price may vary based on the strengths.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works

Gracin 40 MG Injection works by preventing the formation of bacterial cell walls. This helps in stopping the growth and multiplication of the microorganism, eventually killing it.

Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Aminoglycosides, Antibiotics

Schedule

Schedule H

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 19 February 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/062366s033lbl.pdf>

Medicines.org.uk. 2021. Gentamicin 10mg/ml Solution for Injection or Infusion - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 19 February 2021].

https://www.medicines.org.uk/emc/medicine/32933>

Dailymed.nlm.nih.gov. 2021. DailyMed - GENTAMICIN- gentamicin sulfate injection, solution. [online] Available at: < [Accessed 19 February 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=84f5c763-1cd3-4d85-9afb-934db8666fbf#dd8e2f25-906a-42b0-b8ce-684796a010fb>

Drugs, H., 2021. Gentamicin Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 19 February 2021].

https://medlineplus.gov/druginfo/meds/a682275.html>

Go.drugbank.com. 2021. Gentamicin | DrugBank Online. [online] Available at: < [Accessed 19 February 2021].

https://go.drugbank.com/drugs/DB00798>

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Information on this page was last updated on 6 Apr 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.