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Febrex Tm (325/37.5 mg) Tablet
Manufactured byIndoco Remedies Ltd.
ContainsParacetamol (325 mg) + Tramadol (37.5 mg)
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Description
Febrex Tm (325/37.5 mg) Tablet is a combination of Paracetamol and Tramadol. This medicine is a painkiller that helps in relieving moderate to severe pain associated with muscle spasms or injury such as sprains/strains, injury due to accident, etc.
Febrex Tm (325/37.5 mg) Tablet works by blocking the formation of certain chemical substances responsible for pain and swelling. This medicine is most effective when taken along with proper rest and physical therapy.
Febrex Tm (325/37.5 mg) Tablet has some common side effects such as nausea, vomiting, heartburn, stomach pain, loss of appetite, and diarrhoea. Seek a doctor's consultation if these side effects do not resolve with time or get worse. It is recommended not to use this medicine if you have been allergic to it.
Febrex Tm (325/37.5 mg) Tablet should be taken with food to avoid stomach irritation. Your doctor will advise you on the dose and duration of this medicine based on the severity of the pain. For the ease of remembering, take it at around the same time every day. This medicine should be used with extreme caution because it has a high potential for addiction and abuse even at recommended dosages, especially upon prolonged use.
Febrex Tm (325/37.5 mg) Tablet should be used with caution if you have liver and kidney disease. This medicine may increase the risk or worsen stomach ulcers and may cause bleeding therefore, use it with caution.
To make sure Febrex Tm (325/37.5 mg) Tablet is safe for you, share your entire medical and medication history with your doctor. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding.
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Substitutes
List of substitutes for Febrex Tm (325/37.5 mg) Tablet
Side effects
Major & minor side effects for Febrex Tm (325/37.5 mg) Tablet
Nervousness
Dizziness
Headache
Blurred vision
Hot flushes
Shortness of breath
Nausea and Vomiting
Dry mouth
Abdominal pain
Indigestion
Rash
Chest pain
Constipation
Flatulence
Uses of Febrex Tm (325/37.5 mg) Tablet
What is it prescribed for?
Moderate to severe pain
Pain or swelling are the most common symptoms that occur in most population due to various reasons. Febrex Tm (325/37.5 mg) Tablet is one of the best choices of medicines that inhibits the pain signals and helps to reduce moderate to severe pain and swelling associated with ankylosing spondylitis, sports injuries, menstrual cramps, osteoarthritis, rheumatoid arthritis, etc.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The effect of Febrex Tm (325/37.5 mg) Tablet can be observed within 1 hour of administration of the dose. However, you may start feeling well in few hours.How long do the effects of this medicine last?
The effect of Febrex Tm (325/37.5 mg) Tablet lasts for an average duration of 9 hours. But you should take your next dose if needed.Is it safe to consume alcohol while taking this medicine?
Consumption of alcohol is not recommended while treatment with Febrex Tm (325/37.5 mg) Tablet due to the risk of stomach bleeding, dizziness, fatigue, weakness.Is this a habit forming medicine?
Febrex Tm (325/37.5 mg) Tablet may become habit-forming in some cases.Can this medicine be taken during pregnancy?
Febrex Tm (325/37.5 mg) Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your foetus. But in some cases, your doctor may prescribe this medicine during the first 6 months of pregnancy if the benefits outweigh the risks. Discuss the benefits and risks with your doctor before taking this medicine.Can this medicine be taken while breast-feeding?
Febrex Tm (325/37.5 mg) Tablet is known to be excreted in breast milk. It should be avoided in breastfeeding mothers. However, if needed it should only be used upon your doctor's recommendation.
Allergy
Febrex Tm (325/37.5 mg) Tablet can be avoided if you are allergic to it. Seek an immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.
Severe liver disease
Febrex Tm (325/37.5 mg) Tablet is not recommended for use in case of severe liver disease due to the increased risk of worsening of the health condition.
Use in children
Febrex Tm (325/37.5 mg) Tablet is not recommended for use in children less than 12 years of age as effective and safe use are not established.
Warnings for special population
Pregnancy
Febrex Tm (325/37.5 mg) Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your foetus. But in some cases, your doctor may prescribe this medicine during the first 6 months of pregnancy if the benefits outweigh the risks. Discuss the benefits and risks with your doctor before taking this medicine.
Breast-feeding
Febrex Tm (325/37.5 mg) Tablet is known to be excreted in breast milk. It should be avoided in breastfeeding mothers. However, if needed it should only be used upon your doctor's recommendation.
General warnings
Drug dependence and abuse
Febrex Tm (325/37.5 mg) Tablet has a high potential for addiction and abuse even at recommended dosages, especially with prolonged use. Appropriate monitoring, following safety precautions, is recommended to reduce the risk of drug abuse.
Respiratory disorders
Febrex Tm (325/37.5 mg) Tablet should be used with extreme caution in case of respiratory disorders due to the increased risk of worsening of your condition.
Dizziness
Febrex Tm (325/37.5 mg) Tablet may cause sleepiness or dizziness. Avoid driving vehicle and operating heavy machinery after taking this medicine.
Suicidal Tendencies
Febrex Tm (325/37.5 mg) Tablet should be used with extreme caution in patients exhibiting suicidal tendencies due to the increased risk of worsening of the patient's condition.
Withdrawal symptoms
Abrupt withdrawal of Febrex Tm (325/37.5 mg) Tablet may cause withdrawal symptoms. Withdrawal of this medicine should be undertaken gradually using a proper schedule given by your doctor.
Missed Dose
If you have missed Febrex Tm (325/37.5 mg) Tablet dose, make sure that you remember to take the next dose on time. Do not take two doses together to make up for a forgotten dose.
Overdose
Never take Febrex Tm (325/37.5 mg) Tablet more than the prescribed dose. If you suspect that you have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended while treatment with Febrex Tm (325/37.5 mg) Tablet due to the risk of stomach bleeding, dizziness, fatigue, weakness.
Interaction with Medicine
Amitriptyline
Carbamazepine
Ketoconazole
Phenytoin
Warfarin
Sodium Nitrite
Leflunomide
Prilocaine
Monoamine oxidase inhibitors
Disease interactions
Liver Disease
Patients with liver diseases need special consideration while taking Febrex Tm (325/37.5 mg) Tablet. The conversion of this medicine to its active form happens in the liver. Overdose can produce more active forms and leads to liver damage.
Seizures
Maintain caution while using Febrex Tm (325/37.5 mg) Tablet in patients with a history of seizures due to the increased risk of recurrent seizures.
Phenylketonuria
Febrex Tm (325/37.5 mg) Tablet may contain the artificial sweetener aspartame, which is converted to phenylalanine in the gastrointestinal tract. Hence, this medicine should be used with caution in case there is a history of Phenylketonuria (increased levels of phenylalanine in the blood) where the intake of phenylalanine is restricted.
Intracranial pressure
Febrex Tm (325/37.5 mg) Tablet should be used with caution in case of increased intracranial pressure or head injury due to the risk of worsening of your condition.
Acute Alcohol Intoxication
Febrex Tm (325/37.5 mg) Tablet is not recommended for use if there is increased alcohol consumption due to the increased risk of adverse effects.
Food interactions
Information not available.
Lab interactions
Information not available.
It is better to take Febrex Tm (325/37.5 mg) Tablet with milk or food to prevent an upset stomach.
Do not take any other pain killer without asking your doctor first. During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
It is not recommended to use more than the usual daily dose of this medicine and any other Paracetamol (including over the counter) or Tramadol Hydrochloride containing products concurrently without the advice of your doctor.
Miscelleneous
How it works
Febrex Tm (325/37.5 mg) Tablet is a combination of Paracetamol and Tramadol.
Paracetamol helps in reducing the pain signals responsible for the cause of swelling and pain.
Tramadol acts on the brain and nervous system by changing the perception and response to pain.
Legal Status
Classification
Category
Narcotic analgesic combinations
Schedule
Schedule H
Tramadol hydrochloride/Paracetamol 37.5mg/325mg film-coated tablets - Summary of Product Characteristics (SPC) - (eMC) [Internet]. Medicines.org.uk. 2017 [cited 15 September 2017]. Available from:
Tramadol/paracetamol fixed-dose combination: a review of its use in the management of moderate to severe pain. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2017 [cited 15 September 2017]. Available from:
Pubchem.ncbi.nlm.nih.gov. 2021. Tramadol. [online] Available at: < [Accessed 26 May 2021].
Pubchem.ncbi.nlm.nih.gov. 2020. Acetaminophen. [online] Available at: < [Accessed 7 May 2021].
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Information on this page was last updated on 26 Aug 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.