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Disulfiram (Intas) 250 mg Tablet

Manufactured byIntas Pharmaceuticals Ltd.
ContainsDisulfiram
CURRENTLY UNAVAILABLE

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Description

Disulfiram (Intas) 250 mg Tablet is used to treat alcoholism. It discourages you to drink alcohol by reacting with alcohol and causing unpleasant effects such as flushing of the face, vomiting, breathing difficulty, sweating, choking, and anxiety. These effects may start 10 minutes after consumption of alcohol and last for about 1 hour. This medicine only discourages drinking alcohol and is not a cure for alcoholism. Disulfiram (Intas) 250 mg Tablet can cause side effects like fatigue, headache, stomach pain, change in taste, etc. Consult your doctor if these side effects persist or worsen. This medicine can make you feel drowsy; therefore, you should avoid activities like driving vehicles and operating machines. Disulfiram (Intas) 250 mg Tablet can be taken with or without food as instructed by your doctor. Take this medicine at the same time every day to maintain a constant level of medicine in your blood. Do not stop taking this medicine without consulting with your doctor. Avoid consuming any form of alcohol while taking this medicine. Disulfiram (Intas) 250 mg Tablet is not recommended if you are allergic to it. Inform your doctor about all your current medications as they can interact with this medicine and cause side effects. If you are pregnant or breastfeeding, consult your doctor before taking this medicine.

Substitutes

List of substitutes for Disulfiram (Intas) 250 mg Tablet

Esperal 250 mg Tablet
Torrent Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Disulfiram (Intas) 250 mg Tablet

Dark colored urine

Jaundice

Stomach pain

Loss of appetite

Change in taste/ Metallic taste

Headache

Fatigue

Uses of Disulfiram (Intas) 250 mg Tablet

What is it prescribed for?

Alcohol dependence

Alcoholism is the most severe form of alcohol abuse and involves the inability to manage drinking habits due to both physical and emotional dependence on alcohol. It is also commonly referred to as an alcohol use disorder. Disulfiram (Intas) 250 mg Tablet is taken to manage alcoholism or alcohol dependence caused by long-term uncontrolled use of alcohol.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of Disulfiram (Intas) 250 mg Tablet can be observed within 30-60 minutes of taking the dose.
  • How long do the effects of this medicine last?

    The effect of Disulfiram (Intas) 250 mg Tablet lasts for an average duration of 2 weeks.
  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol while on treatment with Disulfiram (Intas) 250 mg Tablet is not recommended as it will cause severe unpleasant side effects such as flushing of the face, vomiting, breathing difficulty, sweating, choking, and anxiety.
  • Is this a habit forming medicine?

    No habit-forming tendencies were reported for Disulfiram (Intas) 250 mg Tablet.
  • Can this medicine be taken during pregnancy?

    Disulfiram (Intas) 250 mg Tablet is not recommended to be taken in pregnancy as it may affect your foetus. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?

    Disulfiram (Intas) 250 mg Tablet is not recommended to be taken while breastfeeding as it is not known if this medicine is present in breast milk or not. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.

Allergy

Disulfiram (Intas) 250 mg Tablet is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, swelling and/or itching (especially of your face, lips, throat), breathing difficulty, etc.

Warnings for special population

Pregnancy

Disulfiram (Intas) 250 mg Tablet is not recommended to be taken in pregnancy as it may affect your foetus. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

Disulfiram (Intas) 250 mg Tablet is not recommended to be taken while breastfeeding as it is not known if this medicine is present in breast milk or not. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.

General warnings

Alcohol use

Do not consume alcoholic beverages or medicines containing alcohol for at least 12 hours before starting therapy with Disulfiram (Intas) 250 mg Tablet and for several weeks after stopping the therapy. Consumption of alcohol during this period may cause severe side effects.

Drowsiness

Disulfiram (Intas) 250 mg Tablet may cause drowsiness or dizziness. It is advised that you do not perform activities that require high mental alertness like driving vehicles or operating machines during treatment with this medicine.

Missed Dose

If you miss a dose of Disulfiram (Intas) 250 mg Tablet, take the missed dose as soon as you remember it. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment immediately in case of an overdose of Disulfiram (Intas) 250 mg Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol while on treatment with Disulfiram (Intas) 250 mg Tablet is not recommended as it will cause severe unpleasant side effects such as flushing of the face, vomiting, breathing difficulty, sweating, choking, and anxiety.

Interaction with Medicine

Leflunomide

Alcohol containing syrups

Paraldehyde

Disease interactions

Disease

Information not available.

Food interactions

Information not available.

Lab interactions

Information not available.
Take Disulfiram (Intas) 250 mg Tablet as advised by your doctor. Do not break, crush or chew the medicine. Follow all the instructions given in the patient leaflet. Do not consume Disulfiram (Intas) 250 mg Tablet after the expiry date. Do not take in larger amounts than advised or share this medicine with others. Keep it away from children and pets. Disulfiram (Intas) 250 mg Tablet is prescribed for a long period. Therefore, do not stop taking this medicine even if you feel better after a few doses. Disulfiram (Intas) 250 mg Tablet is not the cure for alcoholism. It is clubbed with other therapies like counselling for managing alcoholism. Be careful while standing up from a lying or sitting position to avoid feeling dizzy. Consult your doctor if your condition is worsening or not improving after a few days.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works

Disulfiram (Intas) 250 mg Tablet blocks the chemical which breaks the converted form of alcohol in your body. This leads to an increased level of converted form of alcohol in your body causing unpleasant effects while drinking alcohol.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Drugs used in alcohol dependence, Alcohol antagonist, Acetaldehyde dehydrogenase inhibitors

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. [online] Available at: < [Accessed 22 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d2361d16-94fc-43a9-8009-ed03dce0544f&audience=consumer>

Medicines.org.uk. 2021. Disulfiram 200 mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 22 September 2021].

https://www.medicines.org.uk/emc/product/11168>

Drugs, H., 2021. Disulfiram: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 22 September 2021].

https://medlineplus.gov/druginfo/meds/a682602.html>

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Information on this page was last updated on 28 Oct 2021

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