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Curam (400/57 mg) Syrup
Manufactured byNovartis India Ltd.
ContainsAmoxycillin (400 mg) + Clavulanic Acid (57 mg)
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Description
Curam (400/57 mg) Syrup is a combination of Amoxycillin and Clavulanic acid. Curam (400/57 mg) Syrup is used to treat bacterial infections of the lungs and airways, middle ear, sinuses, skin, teeth, and urinary tract. It is also used to treat multidrug-resistant Tuberculosis. This medicine is generally meant to be used in children. However, your doctor may prescribe this medicine to you if you cannot swallow the tablet or capsule.
Curam (400/57 mg) Syrup shows common side effects like nausea, vomiting, stomach pain, and skin rash. Usually, these side effects are self-limiting. Consult the doctor at the earliest if any of these side effects persist or bothers your child. Before giving this medicine to your child, inform your doctor if your child is allergic to any antibiotics.
Curam (400/57 mg) Syrup can be given to your child with food as it improves absorption and decreases the risks of stomach upset. Your child's doctor will decide the dose and frequency based on the severity of infection, body weight and age of your child. Also, ensure that you complete the course of treatment even if your child starts feeling better after taking a few doses.
Curam (400/57 mg) Syrup is safe for your child, however, do share your child’s entire medical history with the doctor, including any previous episode of allergy, heart problem, a blood disorder, birth defects, lung problem, stomach or intestinal problem, skin disorder, liver and kidney problems. This information is critical as it can help your paediatrician in planning an overall treatment and dose adjustments for your child.
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Substitutes
List of substitutes for Curam (400/57 mg) Syrup
Side effects
Major & minor side effects for Curam (400/57 mg) Syrup
Allergic Skin Reaction
Diarrhoea
Fever
Skin yellowing
Easy bruising and bleeding
Tooth discoloration
Nausea or vomiting
Swelling of face, lips, eyelids, tongue, hands and feet
Black or tarry stools
Muscle or joint pain
Sleeplessness
Uses of Curam (400/57 mg) Syrup
What is it prescribed for?
Acute otitis media
Acute Otitis media (AOM), is an infection of the middle ear (the area behind the eardrum), common in infants and young children. Curam (400/57 mg) Syrup is used to treat acute otitis media caused by bacteria.
Sinusitis
Sinusitis is the swelling of membranes that line the nose and surrounding sinuses. It is often caused by bacteria and sometimes, viruses and fungi. It is characterized by a stuffed nose and pain or pressure behind the eyes, nose, cheeks, or forehead. Curam (400/57 mg) Syrup is used to treat bacterial sinusitis in children.
Lower respiratory tract infection
Curam (400/57 mg) Syrup is used to treat Pneumonia and Bronchitis in children.
Pneumonia is an infection of the air sacs in the lungs (either single or both lungs). It can be bacterial and viral. This medicine is used to treat pneumonia caused by bacteria.
Bronchitis is the swelling and irritation of bronchial tubes that regulates air passage in the lungs. It is used to treat bronchitis caused by bacteria.
Skin infections
Skin and soft tissue infections occur when the bacteria invade the skin and its supporting structures. Curam (400/57 mg) Syrup is used to treat all skin infections including abscesses caused by bacteria in children.
Pharyngitis/Tonsilitis
Pharyngitis and tonsillitis are infections that cause swelling and soreness in the throat and tonsils. Curam (400/57 mg) Syrup is used to treat pharyngitis, tonsillitis, and/or pharyngotonsillitis (a condition where the infection affects both the throat and the tonsils) in children.
Urinary tract infection
An infection in any part of the urinary system (kidneys, bladder, ureters, or urethra) is called a urinary tract infection (UTI). UTIs are caused by bacteria and in some cases, viruses or fungi. Curam (400/57 mg) Syrup is used to treat urinary tract infections caused by bacteria in children.
Multidrug resistant Tuberculosis
Multidrug-resistant Tuberculosis is caused by TB bacteria that is resistant to at least isoniazid and rifampin, the two most potent TB medicines. Curam (400/57 mg) Syrup is used to treat tuberculosis in children, which is resistant to first-line TB medicines.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
Curam (400/57 mg) Syrup starts working within 1-2 hours of administration.How long do the effects of this medicine last?
The effect of Curam (400/57 mg) Syrup lasts for an average duration of 6-8 hours.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
Curam (400/57 mg) Syrup has no habit-forming tendency.Can this medicine be taken during pregnancy?
Curam (400/57 mg) Syrup is only recommended for use in children.Can this medicine be taken while breast-feeding?
Curam (400/57 mg) Syrup is only recommended for use in children.
Allergy
Avoid administration of Curam (400/57 mg) Syrup if your child is allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.
Cholestasis
Curam (400/57 mg) Syrup should be avoided if your child has Cholestasis (a condition where the normal flow of bile from the liver is interrupted).
Liver dysfunction
Avoid using Curam (400/57 mg) Syrup if your child has a history of liver problems associated with the use of this medicine or any other antibiotics.
Warnings for special population
Pregnancy
Curam (400/57 mg) Syrup is only recommended for use in children.
Breast-feeding
Curam (400/57 mg) Syrup is only recommended for use in children.
General warnings
Diarrhoea
Curam (400/57 mg) Syrup can cause diarrhoea because it may also kill the helpful bacteria in your child's stomach or intestine. Seek emergency medical help if your child gets diarrhoea by using this medicine.
Antibiotic resistance
Finish the entire course of treatment with Curam (400/57 mg) Syrup, even if your child's condition gets better to avoid antibiotic resistance (bacteria develops the ability to overcome the antibiotic's ability to kill them).
Liver disease
Curam (400/57 mg) Syrup may increase liver enzyme levels and cause liver swelling. If your child has liver problems, caution should be maintained while using Curam (400/57 mg) Syrup due to the risk of liver damage. Your doctor may adjust the dose of this medicine and may closely monitor your child's liver functioning if required, based on the clinical conditions of your child.
Form of medication
Curam (400/57 mg) Syrup is normally used for children. However, adultss who are unable to chew or swallow the solid form can use the liquid form under their doctor's supervision.
Missed Dose
If you forget to give a Curam (400/57 mg) Syrup dose to your child, make sure that you remember to give your next dose on time. Do not give two doses together to make up for a forgotten dose.
Overdose
Never give Curam (400/57 mg) Syrup more than the prescribed dose. If you suspect that you might have given an overdose of this medicine and observing difficulty in the child, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Doxycycline
Methotrexate
Warfarin
Live vaccines
Disease interactions
Colitis
Curam (400/57 mg) Syrup can kill the helpful bacteria in your child's stomach or intestine and lead to diarrhoea. Therefore use this medicine with extreme caution in children with colitis (swelling of the inner lining of the colon).
Kidney diseases
Children with kidney problems need special consideration while taking Curam (400/57 mg) Syrup due to the risk of kidney damage. Dose adjustment will be done by your doctor based on the clinical condition of your child.
Food interactions
Information not available.
Lab interactions
Information not available.
Give Curam (400/57 mg) Syrup to your child with food to decrease the risk of stomach upset. Ensure that you complete the entire course of Curam (400/57 mg) Syrup as abrupt stopping may cause recurrence of the infection, or cause another infection.
Your child may have a bitter taste in the mouth after taking Curam (400/57 mg) Syrup. Eating citrus fruits or fruit juices may help.
Encourage your child to drink plenty of water in case diarrhoea develops as a side effect.
Never give Curam (400/57 mg) Syrup unless prescribed by the doctor. You must also never share your child’s medicine with anyone else even if they show similar symptoms.
Avoid giving Curam (400/57 mg) Syrup to treat the common cold and flu-like symptoms caused by viruses.
Never save Curam (400/57 mg) Syrup for future. It cannot be said whether the same medicine will work on future infections. Discard the medicine if the seal is broken or the appearance of the liquid changes.
Stop Curam (400/57 mg) Syrup immediately if your child develops an itchy rash, facial swelling, or breathing difficulty. Report to the doctor without any delay.
Miscelleneous
How it works
Curam (400/57 mg) Syrup is a combination of Amoxycillin and Clavulanic acid.
Amoxycillin binds to certain specific receptors and prevents the formation of a necessary component for the cell wall building process.
Clavulanic acid is effective against a specific species of bacteria that are resistant to other antibiotic medicines.
Legal Status
Classification
Category
Beta-lactamase inhibitors, Aminopenicillins
Schedule
Schedule H
Drugs, H., 2021. Amoxicillin and Clavulanic Acid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 20 May 2021].
Dailymed.nlm.nih.gov. 2021. DailyMed - AMOXICILLAN AND CLAVULANATE POTASSIUM tablet, film coated. [online] Available at: < [Accessed 20 May 2021].
Ca.gsk.com. 2021. [online] Available at: < [Accessed 31 May 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Clavulanic acid. [online] Available at: < [Accessed 20 May 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Amoxicillin. [online] Available at: < [Accessed 22 January 2021].
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Answer from Dr. Rohan Jaju
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Information on this page was last updated on 26 Oct 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.