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Amikapen 500 MG Injection

Manufactured byMorepen Laboratories Ltd.
ContainsAmikacin
CURRENTLY UNAVAILABLE

Description

Amikapen 500 MG Injection is an antibiotic. It is used to prevent or treat a wide variety of bacterial infections such as infections of the lungs, skin, abdomen, blood, brain, urinary tract, bones and joints. It works by blocking the production of essential proteins required for bacterial growth. This prevents further growth and kills the infection-causing bacteria. It is not effective against infections caused by viruses. Amikapen 500 MG Injection may cause side effects like pain at the injection site, skin rash, headache, weakness, etc. Consult your doctor if these symptoms persist or worsen. Avoid driving vehicles or operating machines as this medicine may make you feel drowsy or dizzy. Amikapen 500 MG Injection is administered by your doctor in a clinic or a hospital setting. The dose and duration of the treatment will depend on your condition. Follow the instructions given by your doctor. This medication is effective only for the treatment of infections caused by bacteria and not viruses. Amikapen 500 MG Injection is not recommended if you are allergic to it. Inform your doctor if you have pre-existing kidney, ear, or nerve and muscle problems before beginning treatment with this medicine. If you are pregnant or breastfeeding, or are planning a pregnancy, consult your doctor before receiving this medication.
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Substitutes

List of substitutes for Amikapen 500 MG Injection

Amicip 500 MG Injection
Cipla Ltd.
Amikacin 500 MG Injection
Cadila Pharmaceuticals Ltd.
Amikamac 500 MG Injection
Macleods Pharmaceuticals Pvt. Ltd.
Amitrust 500 MG Injection
Zuventus Healthcare Ltd.
Zekacin 500 MG Injection
Wockhardt Ltd.

Side effects

Major & minor side effects for Amikapen 500 MG Injection

Black or tarry stools

Decrease in frequency of urination

Dizziness

Difficulty in breathing

Hearing loss

Muscle pain

Unusual tiredness and weakness

Skin rash

Pain at the injection site

Uses of Amikapen 500 MG Injection

What is it prescribed for?

Intra-abdominal Infection

Intra-abdominal infection is a broad term that includes infections of the organs of the abdomen. It includes peritonitis (swelling of the lining of the abdominal wall), diverticulitis (swelling of diverticula- one or more small pouches in the intestine), cholecystitis (swelling of the gallbladder), cholangitis (swelling of the bile duct system), and pancreatitis (swelling of the pancreas). Amikapen 500 MG Injection is used in the treatment of these infections.

Lower Respiratory Tract Infection

Amikapen 500 MG Injection is used in the treatment of lower respiratory tract infections such as pneumonia (lung infection), community-acquired pneumonia (lung infection that is acquired outside the hospital), bronchitis (a condition with swelling of the bronchial tubes, the passages that carry the air to and from the lungs).

Bacteremia

Bacteremia is the presence of bacteria in the blood. Bacteria can sometimes enter your bloodstream from dental or medical procedures, or from infections. If this condition left untreated it can lead to septicemia which is an infection of the blood caused by bacteria. Amikapen 500 MG Injection is used for the treatment of bacteremia.

Bone and joint infections

Bone and joint infections occur in the bones and joints. Osteomyelitis is an infection of the bone and septic arthritis is an infection in a joint. These infections can occur due to a bone/joint injury or through blood by which bacteria, virus, or fungi invade a bone/joint. Amikapen 500 MG Injection is used for the treatment of osteomyelitis and septic arthritis caused by bacteria.

Urinary tract infections

An infection in any part of your urinary system- the kidneys, bladder, ureters, or urethra is called a urinary tract infection (UTIs). Amikapen 500 MG Injection is used to treat urinary tract infections caused by bacteria.

Bacterial Meningitis

Meningitis is a swelling of the protective membranes that surround your brain and spinal cord due to an infection. Amikapen 500 MG Injection is used in the treatment of bacterial meningitis.

Skin and soft tissue infections

Skin and soft tissue infections are bacterial infections of the skin and its supporting structures. Amikapen 500 MG Injection is used in the treatment of skin and soft tissue infections.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of Amikapen 500 MG Injection starts immediately after the administration.

  • How long do the effects of this medicine last?

    The effect of Amikapen 500 MG Injection lasts for an average duration of 8 to 12 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit-forming tendency has been reported for Amikapen 500 MG Injection.

  • Can this medicine be taken during pregnancy?

    Amikapen 500 MG Injection may cause severe side effects in your developing foetus. This medicine is not recommended during pregnancy unless necessary. If you are pregnant, consult your doctor.

  • Can this medicine be taken while breast-feeding?

    Amikapen 500 MG Injection passes into breastmilk and may cause side effects in your breastfed infant. This medicine is not recommended during breastfeeding unless necessary. If you are breastfeeding, consult your doctor.

Allergy

Avoid receiving Amikapen 500 MG Injection if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Warnings for special population

Pregnancy

Amikapen 500 MG Injection may cause severe side effects in your developing foetus. This medicine is not recommended during pregnancy unless necessary. If you are pregnant, consult your doctor.

Breast-feeding

Amikapen 500 MG Injection passes into breastmilk and may cause side effects in your breastfed infant. This medicine is not recommended during breastfeeding unless necessary. If you are breastfeeding, consult your doctor.

General warnings

Hearing loss

High doses of Amikapen 500 MG Injection may cause damage to your hearing. Your doctor will perform regular hearing tests during treatment.

Antibiotic resistance

Antibiotic resistance is a condition in which the antibiotic is not effective against the bacteria. This can be avoided by finishing the entire course of treatment with Amikapen 500 MG Injection even if your symptoms get better. Alternatively, if your symptoms do not get better even after the prescribed duration, consult your doctor.

Other medicines

Amikapen 500 MG Injection may interact with other medicines and cause undesired effects. Hence, inform your doctor about your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Since Amikapen 500 MG Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since Amikapen 500 MG Injection is given in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Ceftriaxone

Furosemide

Aspirin

Adefovir

Vancomycin

Disease interactions

Impaired kidney function

Amikapen 500 MG Injection may increase your risk of kidney damage. This risk is especially higher if you have pre-existing kidney problems. Inform your doctor if you experience any signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased/decreased urination, sudden weight gain/weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.

Neuromuscular disorders

Amikapen 500 MG Injection may increase your risk of muscle weakness. This risk is especially higher if you have neuromuscular problems such as myasthenia gravis (a condition that causes weakness in your skeletal muscles, the muscles your body uses for movement), parkinsonian syndrome (a condition that affects your body movement), etc. Inform your doctor if you experience any worsening of your condition while on treatment with this medicine.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Amikapen 500 MG Injection is administered in the clinic/hospital setting under the supervision of a qualified healthcare professional. Do not discontinue this medicine without consulting your doctor. If you experience any reactions at the site of injection (redness/pain/swelling) that become bothersome, inform your doctor immediately. Amikapen 500 MG Injection may cause diarrhoea. Consult your doctor if you experience a severe worsening of your condition. Amikapen 500 MG Injection may affect your hearing. Inform your doctor if you experience any hearing problems while on treatment with this medicine. Amikapen 500 MG Injection may affect your kidney function. Your kidney function needs to be closely monitored.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works

Amikapen 500 MG Injection works by preventing the formation of bacterial cell walls. This helps in stopping the growth and multiplication of the microorganism, eventually killing it.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Aminoglycosides, Antibiotics

Schedule

Schedule H

Sandoz.ca. 2021. [online] Available at: [Accessed 7 January 2021].

https://www.sandoz.ca/sites/www.sandoz.ca/files/Amikacin_PM_ENG.pdf

Medicines.org.uk. 2021. Amikacin 250 Mg/Ml Injection - Summary Of Product Characteristics (Smpc) - (Emc). [online] Available at: [Accessed 7 January 2021].

https://www.medicines.org.uk/emc/medicine/619

Medicines.org.uk. 2021. Amikacin 250 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 9 February 2021].

https://www.medicines.org.uk/emc/product/3784

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Information on this page was last updated on 5 Jan 2023

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.