Amikacin

Description

Amikacin is used to treat a variety of bacterial infections of lungs, skin, abdomen, and blood caused by E.coli, Streptococci, Enterococci, etc. This medicine is known to cause serious kidney problems and hearing problems, especially in the elderly population. Hence, it should be used with extreme caution in elderly patients as well as in patients with kidney diseases.

Side effects

Major & minor side effects for Amikacin

  • Black or tarry stools
  • Blurred vision
  • Decrease in frequency of urination
  • Dizziness
  • Difficulty in breathing
  • Hearing loss
  • Muscle pain
  • Unusual tiredness and weakness
  • Skin Rash
  • Vomiting
  • Eyelid Edema
  • Eye pain
  • Visual disturbances
  • Corneal Scar
  • Dilated pupils

Uses of Amikacin

What is it prescribed for?

  • Intra-abdominal Infection
  • Pneumonia
  • Bacteremia
  • Bone and Joint infections
  • Bacterial Conjunctivitis
  • Bacterial Keratitis
  • Blepharoconjunctivitis
  • Strabismus Surgery
Read More
Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed within 45 to 120 minutes after intramuscular administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 8 to 12 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to amikacin, any other aminoglycosides, or any other inactive ingredients present along with it.

Impaired Kidney function

The parenteral form (injection) of this medicine is not recommended for use in patients with a known history of renal impairment due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.
General warnings

Allergy

This medicine is not recommended for use in patients with a known allergy to amikacin or any other aminoglycosides. Seek immediate medical attention if you experience any allergic symptoms such as a rash, itching, nausea or vomiting, swelling of lips, hands, and feet, etc.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Impaired kidney function

This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Myasthenia gravis

This medicine should be used with extreme caution in patients with a history of myasthenia gravis due to the increased risk of worsening of the patient's condition. Any unusual symptoms should be reported to the doctor on priority. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Pediatric use

Caution is advised while using this medicine in pediatric patients due to the increased risk of kidney injuries.

Driving or Operating machinery

Use of this medicine may cause symptoms such as dizziness, drowsiness, blurred vision, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Intravenous Administration

This medicine should be administered only by a slow intravenous infusion over a period of 30 to 60 minutes for adults and adolescents. Infants should be infused over a duration of 1 to 2 hours.

Contact Lens

While using the ophthalmic form of this medicine, usage of contact lens is not recommended if any signs and symptoms of an eye infection such as eye redness, irritation, drainage, etc. are present.

Missed Dose

Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low. Eye Drops: Administer the missed dose as soon as you remember. It is advisable to skip the missed dose if it is almost time for your next scheduled dose. Do not instill a double dose to make up for the missed one.

Overdose

Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected. Eye Drops: The likelihood of an overdose with the ophthalmic form of this medicine is very low. However, seek emergency medical treatment or contact the doctor if you suspect an overdose of this medicine.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Ceftriaxone

Ethinyl Estradiol

Furosemide

Aspirin

Adefovir

Disease interactions

Myasthenia Gravis

This medicine should be used with caution in patients with a known history of disorders such as myasthenia gravis or parkinsonism due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered based on the clinical condition.

Impaired kidney function

This medicine should be used with extreme caution in patients with kidney diseases or patients undergoing treatment with NSAIDs for a long time due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Injection: This medicine should be administered by a qualified healthcare professional. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Eye Drops: Use this medicine exactly as prescribed. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
It interferes with the production of certain vital components necessary for the susceptible bacteria to grow and results in the eventual death of the bacteria.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Aminoglycosides

Schedule

Schedule H

DailyMed - Amikacin sulfate injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 2 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0b56f6df-a05d-4520-8bf0-d7cefe20f6ad

[Internet]. 2017 [cited 2 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/619#PRODUCTINFO

Amikacin Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 2 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682661.html

Amikacin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 23 May 2018]. Available from:

https://www.drugbank.ca/drugs/DB00479

Jawa Pharmaceuticals (India) Pvt. Ltd.- Manufacturer and supplier of eye drops, eye lubricant, ear drops, eye ointment, ear ointment Jaipur,Noida,Rajasthan,India, Antibacterial eye drops, Antibacterial eye ointment, Antibacterial and steroid drops, Antibacterial and steroid ointment, Antibacterial and NSAID drops, NSAID Drops, Antiallergic eye drops, Anti Catract eye drops, Antibacterial eye drop, Corneal conjuctivial OEDEMA, Mydriatic & cycloplegic drops, Antifungal, Anti glaucoma, Antiviral ointment, eye lubricant, eye drops, ear drops, eye ointment, ear ointment Jaipur,Noida,Rajasthan,India, Eye drops manufacturer, ear drops manufacturer, eye drops suppliers, ear drops suppliers, eye ointment manufacturer, ear ointment manufacturer, eye ointment suppliers, ear ointment suppliers, manufacturer of eye drops, supplier of eye drops, manufacturer of ear drops, supplier of ear drops, manufacturer of eye ointment, supplier of eye ointment, manufacturer of ear ointment, suppliers of ear ointment, eye drops manufacturer jaipur.html,Noida,Rajasthan,India, Ear Drops Manufacturer Jaipur,Noida,Rajasthan,India , Ear ointment Manufacturer Jaipur,Noida,Rajasthan,India, Eye ointment Manufacturer Jaipur,Noida,Rajasthan,India , Eye Drops Supplier Jaipur,Noida,Rajasthan,India, Ear Drops Supplier Jaipur,Noida,Rajasthan,India [Internet]. Jawapharma.com. 2018 [cited 23 May 2018]. Available from:

http://www.jawapharma.com/manufacturer%20and%20supplier%20of%20antibacterial%20eye%20drops.html

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 23 May 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.