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Accentrix Solution for Injection

Manufactured byNOVARTIS INDIA LTD
ContainsRanibizumab
CURRENTLY UNAVAILABLE

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Description

Accentrix Solution for Injection is used to treat certain types of eye disorders. It is used for the treatment of a wet type of age-related macular degeneration, an eye disease that impairs central vision. It is also used for the treatment of swelling in the retina resulting due to diabetes or by blockage of blood flow from the eye.

Substitutes

List of substitutes for Accentrix Solution for Injection

Side effects

Major & minor side effects for Accentrix Solution for Injection

Blindness

Blurred vision

Dizziness

Eye pain

Irregular heartbeat

Unexplained weight loss

Back pain

Uses of Accentrix Solution for Injection

What is it prescribed for?

Neovascular (Wet) Age-Related Macular Degeneration (AMD)

This medicine is used for the treatment of a wet type of age-related macular degeneration, an eye disease that impairs central vision making difficult to read, drive, or perform other daily activities.

Diabetic retinopathy

This medicine is used for the treatment of diabetic retinopathy (a condition of damage to the retina due to diabetes) in patients with or without diabetic macular edema.

Macular Edema

This medicine is used for the treatment of macular edema, a condition that occurs due to the accumulation of fluids in the macula, an area in the center of the retina which may result in vision loss.

Diabetic macular edema

This medicine is used for the treatment of diabetic macular edema (DME), a condition that occurs due to the accumulation of fluids in the macula, an area in the center of the retina in patients with diabetes.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?

    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?

    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to Ranibizumab or any other inactive ingredient present along with it.

Ocular infection or Periocular infections

This medicine is not recommended for use in patients with infectious eye diseases due to the increased risk of worsening of the patient's condition.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

General warnings

Thromboembolic events

This medicine may cause serious arterial thromboembolic events in some patients. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Increase in intraocular pressure

This medicine may increase the intraocular pressure and hence should be used with extreme caution in patients with glaucoma (increased intraocular pressure) due to the increased risk of worsening of the patient's condition. It is recommended to monitor the intraocular pressure before and after therapy with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Visual disturbances

This medicine may cause temporary visual disturbances in some patients on therapy. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any such symptoms.

Use in children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. However, it is advised to contact the doctor immediately if you miss a scheduled dose of this medicine.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Verteporfin

Disease interactions

Glaucoma

This medicine should be used with extreme caution in patients with glaucoma (increased intraocular pressure) due to the increased risk of worsening of the patient's condition. It is recommended to monitor the intraocular pressure before and after therapy with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Food interactions

Information not available.

Lab interactions

Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Effect on sleep is not established

How it works

This medicine works by inhibiting the abnormal blood vessel formation and leakage within the eyes to prevent vision loss.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Anti-angiogenic ophthalmic agents

Schedule

Schedule H

Lucentis 10 mg/ml solution for injection - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 26 December 2018]. Available from:

https://www.medicines.org.uk/emc/product/307/smpc#CLINICAL_PRECAUTIONS

Ranibizumab - DrugBank [Internet]. Drugbank.ca. 2018 [cited 26 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB01270

[Internet]. Accessdata.fda.gov. 2018 [cited 26 December 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/125156s111lbl.pdf

DailyMed - Lucentis- ranibizumab injection, solution [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 26 December 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=de4e66cc-ca05-4dc9-8262-e00e9b41c36d

Related Questions

Question:
I consult with many retina doctors and they advice me for accentrix injection , i want to know that ...more
Answer from Dr. Hegde Sharat Shivaramaiah
These injections are safer.. Buy any intervention is not 100 percent safe.. 99.9...more
Question:
Hello, My wife had viral fever and she has issue with vision in one eye.Viral fever lasts only fo...more
Answer from Dr. Vaibhev Mittal
Hello 1. you can use this injection without fear....side effects are there but t...more
Question:
Patient is diabetic and dr advice accentrix inj into retina .He said blood spot seen on retina ...I ...more
Answer from Dr. Vaibhev Mittal
Hello. As per this report, patient has macular edema and for that intravitreal i...more
Question:
My mother have abnormal nurve bleeding in the eye, so doctor advice about accentrix injection, i wan...more
Answer from Dr. A K Goel
The injection is safe but the recovery depends upon the  damage  caused by disea...more
Question:
Doctors detected grayish membrane near nasal to fovea.. Associated with heme at the fovea adjacent t...more
Answer from Dr. A K Goel
eccentric and lucentis are same but cois diffrent accentrix being  $4000 and luc...more
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Information on this page was last updated on 30 May 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.