Amorolfine

Description

Amorolfine is used to treat a fungal infection (onychomycosis) that causes thickened, brittle, and ragged nails. It may also be used to treat certain specific fungal infections of the skin.

Side effects

Major & minor side effects for Amorolfine

  • Skin irritation and rahses
  • Red spots on skin
  • Burning sensation of skin
  • Discoloration of the nails
  • Broken and brittle nails
  • Blisters under the skin
  • Hives

Uses of Amorolfine

What is it prescribed for?

  • Onychomycosis
  • Dermatomycosis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time taken by this medicine to show its effect is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains effective is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken such that the infant does not come into contact with the medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to amorolfine or any other inactive ingredients present along with it.

Pediatric use

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken such that the infant does not come into contact with the medicine.
General warnings

Use in children

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Allergic reaction

Use of this medicine may cause an allergic reaction around the area of application. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Monitoring of patient's clinical condition

If this medicine is used for treating fungal infections in patients suffering from medical conditions such as diabetes mellitus, immunosuppression, peripheral circulatory disorders, etc., the patient's underlying clinical condition should be monitored closely. In such patients, appropriate patient/caregiver counseling, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Other nail products

Use of other nail products such as varnish or artificial nails should be avoided during treatment with this medicine.

External Use

This medicine is meant for external use only. Avoid the contact of this medicine with your eyes, mouth, broken skin, or wounds.

Missed Dose

Apply the missed dose as soon as you remember. If it is almost time for the next scheduled application, the missed one can be skipped. Do not use extra medicine to make up for the missed dose.

Overdose

An overdose of this medicine is unlikely to cause severe symptoms. However, if you accidentally swallow this medicine, contact your doctor or seek emergency medical intervention.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Apply this medicine exactly as prescribed by the doctor. Avoid contact of this medicine with the eyes, ears, mouth, or broken skin. Report any unusual symptoms to the doctor immediately. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine stops the production of a certain vital component of the fungal cell wall. This inhibits the growth of the fungus and eventually leads to its death.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Topical antifungals

Schedule

Schedule H

Amorolfine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 11 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Amorolfine#section=3D-Conformer

Amorolfine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 11 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB09056

[Internet]. Mhra.gov.uk. 2018 [cited 11 September 2018]. Available from:

http://www.mhra.gov.uk/home/groups/par/documents/websiteresources/con2023787.pdf

M H. Amorolfine. A review of its pharmacological properties and therapeutic potential in the treatment of onychomycosis and other superficial fungal inf... - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2018 [cited 11 September 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/7705210

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Information on this page was last updated on 12 Sep 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.