Amodiaquine

Description

Amodiaquine is an antimalarial medication used to treat acute malarial attacks characterized by symptoms such as chills, fever, and sweating. This medicine can be used alone or in combination with other antimalarial agents. It is not recommended for use in the prevention of malaria.

Side effects

Major & minor side effects for Amodiaquine

  • Irregular heartbeat
  • Blurred vision
  • Blindness
  • Eye pain
  • Nausea and vomiting
  • Abdominal pain
  • Diarrhea
  • Decreased appetite
  • Muscle weakness
  • Headache
  • Dizziness
  • Rash
  • Drowsiness

Uses of Amodiaquine

What is it prescribed for?

  • Malaria
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to amodiaquine or any other inactive ingredients present along with it.

Malaria prophylaxis

This medicine is not recommended for use in the prevention of malaria.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver impairment since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver impairment

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. It is not recommended for use in patients with severe liver impairment. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Kidney impairment

This medicine should be used with caution in patients with renal diseases due to the increased risk of severe adverse effects. Close monitoring of renal function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Agranulocytosis

This medicine may cause agranulocytosis (dangerously low white blood cell count) in some patients. Close monitoring of complete blood cell counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Driving or Operating machinery

This medicine may rarely cause symptoms such as dizziness or drowsiness. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Isoniazid

Artemether

Efavirenz

Amlodipine

Chloroquine

Disease interactions

HIV infection

This medicine should be used with extreme caution in patients suffering from an HIV infection due to the increased risk of liver toxicity. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by increasing the concentration of a substance that inhibits the growth of the malarial parasite.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antimalarial agents, 4-Aminoquinolines

Schedule

Schedule H

Amodiaquine Hydrochloride (PIM 030) [Internet]. Inchem.org. 2018 [cited 10 April 2018]. Available from:

http://www.inchem.org/documents/pims/pharm/amodiaqn.htm

Amodiaquine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 10 April 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/amodiaquine

Amodiaquine [Internet]. Livertox.nih.gov. 2018 [cited 10 April 2018]. Available from:

https://livertox.nih.gov/Amodiaquine.htm

Amodiaquine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 10 April 2018]. Available from:

https://www.drugbank.ca/drugs/DB00613

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Information on this page was last updated on 24 Apr 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.