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Amlozaar-H Tablet
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Amlozaar-H Tablet

Manufactured byMICRO LABS LTD
ContainsAmlodipine (5 mg) + Losartan (50 mg) + Hydrochlorothiazide (12.5 mg)
Description
Amlozaar-H Tablet is a combination of Amlodipine, Losartan and Hydrochlorthiazide. This medicine is used in the treatment of high blood pressure. It relaxes your blood vessels, heart muscles and decreases your blood pressure. It also removes extra water and certain electrolytes from your body through urine. Amlozaar-H Tablet may cause some side effects like cough, stomach pain, diarrhoea, nausea, etc. This medicine may also cause dizziness, drowsiness or confusion. Do not perform any work that requires mental focus if you feel dizzy or drowsy. Most of these side effects do not need medical attention and resolve with time. However, if any of these symptoms persist for a long time or worsen, consult your doctor at the earliest. Amlozaar-H Tablet is recommended to be taken with or without food. Your doctor will decide the dose based on your clinical condition. Do not self-medicate or stop on your own even if you feel better. Amlozaar-H Tablet is not recommended during pregnancy and breastfeeding. Avoid drinking alcohol while on treatment with this medicine as it may further decrease your blood pressure. Amlozaar-H Tablet has an impact on pre-existing medical conditions. Inform your doctor about any medical conditions that you may have, like diabetes and heart, liver and kidney problems, before taking this medicine. Your doctor will regularly monitor your heart function and blood pressure while you are on this medication.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Amlozaar-H Tablet

  • Stomach pain
  • Difficulty or painful urination
  • Muscle pain
  • Back pain
  • Cough
  • Dizziness
  • Drowsiness
  • Headache
  • Anxiety
  • Sweating
  • Redness of face, neck, arms and chest
  • Swelling of ankles or feet

Uses of Amlozaar-H Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Amlozaar-H Tablet can be observed in 4-8 hours
  • How long do the effects of this medicine last?
    The average time for which Amlozaar-H Tablet stays in your body is 1-2 days.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Amlozaar-H Tablet due to the increased risk of side effects such as dizziness, lightheadedness, and fainting.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Amlozaar-H Tablet.
  • Can this medicine be taken during pregnancy?
    Amlozaar-H Tablet is not recommended for use in pregnancy as it may cause death or altered body part development in the foetus. Discuss all the potential benefits and risks with your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    It is not known if Amlozaar-H Tablet passes into breastmilk. Consult your doctor regarding the continuation of this medicine while you are breastfeeding.

Allergy

Do not take Amlozaar-H Tablet if you are allergic to this medicine. Seek medical attention if you notice allergic reactions such as skin rash, hives (painful eruptions that itch and sting), swelling ( of your face, lips, tongue, etc.), breathing difficulty, etc.

Aliskiren

Aliskiren (a medicine used for reducing high blood pressure) is a first-line medicine used in the treatment of hypertension. Taking Amlozaar-H Tablet and Aliskiren together is not recommended as it may lead to kidney damage, increase in your blood pressure and hyperkalaemia (high potassium levels in the blood). This may cause other side effects such as irregular heartbeat, muscle paralysis, heart attack, etc. This risk is especially higher in the elderly population, in people with diabetes and kidney problems.

Anuria

Anuria is a condition where the kidney is unable to produce urine. Amlozaar-H Tablet should be avoided for use if you have anuria. This medicine may cause certain severe side effects and worsen your condition.

Severe Kidney disease

Amlozaar-H Tablet is excreted through the kidneys. This medicine is not recommended if you have kidney problems, as it may accumulate in the kidneys leading to other undesirable effects and may further worsen your condition.
Warnings for special population

Pregnancy

Amlozaar-H Tablet is not recommended for use in pregnancy as it may cause death or altered body part development in the foetus. Discuss all the potential benefits and risks with your doctor before taking this medicine.

Breast-feeding

It is not known if Amlozaar-H Tablet passes into breastmilk. Consult your doctor regarding the continuation of this medicine while you are breastfeeding.
General warnings

Hyperkalemia

Hyperkalemia is an increase in potassium levels in your blood. Amlozaar-H Tablet may cause hyperkalemia and lead to side effects such as cardiac rhythm irregularities (changes in the heartbeat). It is advised that you avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine.

Liver Disease

Amlozaar-H Tablet is absorbed in the liver and improper liver function can lead to its accumulation. Avoid taking this medicine if you have severe liver problems.

Driving or operating machines

Amlozaar-H Tablet may cause dizziness or drowsiness. It is advised that you do not perform activities that require high mental alertness like driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.

Myocardial infarction and angina

Myocardial infarction (MI) is also known as a heart attack. It occurs due to permanent damage to the heart muscle. Angina is chest pain or discomfort caused by a lack of oxygen-rich blood to your heart muscle. Amlozaar-H Tablet should be used with caution in such conditions, especially while starting the treatment or increasing the dose because it may worsen the symptoms of myocardial infarction or angina.

Volume and electrolyte depletion

Amlozaar-H Tablet may alter the blood volume and electrolyte levels. This may cause dizziness, dry mouth, and acid-base imbalance. This risk is especially higher if you have pre-existing kidney and liver problems.

Missed Dose

Take the missed dose of Amlozaar-H Tablet as soon as you remember. If the time for your next dose is near, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Overdose of this medicine may cause dizziness, decreased heart rate and vasodilation (dilation of blood vessels). Seek emergency medical help if you suspect that you might have taken an overdose of Amlozaar-H Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Amlozaar-H Tablet due to the increased risk of side effects such as dizziness, lightheadedness, and fainting.
Interaction with Medicine

Carbamazepine

Dexamethasone

Rifampicin

Captopril

Insulin

Nonsteroidal anti-inflammatory medicines

Disease interactions

Congestive heart failure

Congestive heart failure is a condition in which the heart does not pump enough blood to meet the demands of your body. Taking Amlozaar-H Tablet in this condition may increase the risk of a heart attack. Your heart function will be closely monitored by your doctor in such conditions.

Hypotension

Amlozaar-H Tablet is not recommended for use if you have hypotension (low blood pressure) as it will further decrease your blood pressure. In case you are taking diuretics (water pills) or are being treated for volume depletion (loss of fluids in your body due to severe diarrhoea/vomiting, burns, kidney problems, etc), this medicine is not advisable for you. .

Coronary Artery Disease

Coronary artery disease is a condition in which there is an insufficient blood supply to your heart due to narrowing or blockage of blood vessels (coronary artery). Taking Amlozaar-H Tablet may cause severe hypotension (low blood pressure). Your heart function will be closely monitored by your doctor in such conditions.

Diabetes

Diabetes is a condition in which your blood sugar levels are increased. Amlozaar-H Tablet may cause an increase in blood sugar levels if you have Diabetes. Generally, these effects are reversible after discontinuing this medication. Your doctor will monitor your blood sugar levels regularly while you are on treatment with this medicine.

Hyperuricemia

Hyperuricemia is a condition in which there is an excess of uric acid in your blood. Take Amlozaar-H Tablet with caution if you have had kidney problems due to the increased risk of hyperuricemia.
Food interactions
Grapefruit juice may decrease the effect of Amlozaar-H Tablet. Hence avoid consuming grapefruit juice while taking this medicine.
Avoid taking high potassium containing food or potassium supplements with Amlozaar-H Tablet as it may cause an increase in the potassium levels in your blood. Consult your doctor if you have symptoms such as weakness, irregular heartbeat, confusion, tingling sensation or feeling of heaviness in your legs.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Amlozaar-H Tablet exactly as advised by your doctor. Do not take in larger amounts than prescribed. Monitoring of kidney function and electrolytes levels is necessary while taking this medicine. Report any side effects to your doctor. Do not stop the use of this medicine without consulting your doctor. This medicine may cause dizziness. Get up slowly when rising from a sitting or lying position. Amlozaar-H Tablet may cause dehydration. To avoid this, drink plenty of fluids. Inform your doctor if you experience any symptoms like extreme thirst, muscle weakness or very dry mouth.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Amlozaar-H Tablet is a combination of Amlodipine, Losartan and Hydrochlorthiazide. Amlodipine and Losartan both relax the blood vessels, thus improve blood flow and reduce blood pressure levels. Hydrochlorothiazide increases the excretion of excess water and sodium through your urine. Their combination is thus effective in reducing blood pressure and the strain on your heart.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Calcium channel blocking agents, Angiotensin receptor blockers, Thiazide diuretics, Antihypertensive combinations

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Hydrochlorothiazide. [online] Available at: < [Accessed 24 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Hydrochlorothiazide>

Drugs, H., 2021. Amlodipine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 15 September 2021].

https://medlineplus.gov/druginfo/meds/a692044.html>

Drugs, H., 2021. Losartan: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 15 September 2021].

https://medlineplus.gov/druginfo/meds/a695008.html>

Dailymed.nlm.nih.gov. 2021. These highlights do not include all the information needed to use LOSARTAN POTASSIUM TABLETS safely and effectively. See full prescribing information for LOSARTAN POTASSIUM TABLETS. LOSARTAN POTASSIUM tablets, for oral use Initial U.S. Approval: 1995. [online] Available at: < [Accessed 15 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3cdcf8cc-4964-4c53-e054-00144ff88e88>

Pubchem.ncbi.nlm.nih.gov. 2021. Losartan. [online] Available at: < [Accessed 24 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Losartan>

Dailymed.nlm.nih.gov. 2021. DailyMed - hydrochlorothiazide- Hydrochlorothiazide tablet. [online] Available at: < [Accessed 15 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7b38ac8a-4540-4eb2-aedd-9aa966d22190>
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Information on this page was last updated on 28 Sep 2021

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