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Amlodac CH Tablet
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Amlodac CH Tablet

Manufactured byZydus Cadila
ContainsAmlodipine (5 mg) + Chlorthalidone (12.5 mg)
Description
Amlodac CH Tablet is a combination medicine used for the treatment of high blood pressure, angina pectoris, etc. Frequent monitoring of blood pressure and electrolytes level is necessary while taking this medicine. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Amlodac CH Tablet

  • Difficulty in breathing
  • Dizziness
  • Increased heartbeat
  • Redness of face, neck, arms and chest
  • Muscle pain
  • Heartburn
  • Acid or sour stomach
  • Stomach pain
  • Anxiety
  • Constipation or diarrhea
  • Low blood pressure
  • Photosensitivity
  • Loss of appetite
  • Nausea and Vomiting
  • Blurred vision
  • Restlessness
  • Headache

Uses of Amlodac CH Tablet

What is it prescribed for?

  • Hypertension
  • Angina pectoris
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 2 hours of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 24 to 72 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, fainting, and very low blood pressure levels. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to amlodipine, chlorthalidone, other sulfonamides, or any other inactive ingredients present in the formulation.

Anuria

This medicine is not recommended for use in patients with anuria (a condition where the kidney is unable to produce urine) due to the increased risk of worsening of the patient's condition.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver impairment due to the increased risk of serious adverse effects.

Severe renal impairment

This medicine is not recommended for use in patients with severe renal impairment (CrCl < 30 ml/min) due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Low blood pressure

This medicine should be used with extreme caution in patients with severe aortic stenosis due to the increased risk of a very low blood pressure. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments may be required based on the clinical condition.

Myocardial infarction or angina

This medicine should be used with caution in patients with coronary artery diseases, especially while starting the treatment or increasing the dose, since it may worsen the symptoms of myocardial infarction or angina.

Liver Disease

This medicine should be used with caution in patients with liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Volume and electrolyte disturbances

This medicine may alter the blood volume and electrolyte levels in some patients. This may cause dizziness, dry mouth, and acid-base imbalance. This risk is especially higher in patients suffering from kidney and liver diseases. Close monitoring of blood pressure and electrolyte levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with Kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery during treatment with this medicine if you experience any of these symptoms.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any adverse effects.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, fainting, and very low blood pressure levels. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.
Interaction with Medicine

Dexamethasone

Insulin

Ziprasidone

Carbamazepine

Itraconazole

Amiodarone

Cisapride

Rifampicin

Lithium

Disease interactions

Coronary Artery Disease

This medicine should be used with caution in patients with coronary artery disease due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hypotension or cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock (a condition where the heart cannot pump enough blood) due to the increased risk of worsening of the patient’s condition. Replacement with a suitable alternative may be necessary based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is advised for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hyperlipidemia

This medicine should be used with caution in patients with hyperlipidemia since it may increase the cholesterol and triglyceride levels. Close monitoring of cholesterol and triglyceride levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hyperuricemia

This medicine should be used with caution in patients with hyperuricemia (increased uric acid levels in the blood) since this medicine decreases the uric acid excretion and increase the risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as advised by your doctor. Do not take in larger amounts than prescribed. Drink an adequate amount of water. Monitoring of kidney function and electrolytes levels is necessary while taking this medicine. Report any adverse effects to the doctor on priority. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Amlodipine works by blocking the entry of calcium into the muscles and brings about relaxation of the muscles. Chlorthalidone works by increasing the excretion of water and sodium from the kidneys. This helps in bringing down the blood pressure as well as swelling.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Antihypertensive combinations, Calcium channel blocking agents, Thiazide diuretics

Schedule

Schedule H

Chlorthalidone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 19 October 2017]. Available from:

https://www.drugbank.ca/drugs/DB00310

DailyMed - Chlorthalidone tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 19 October 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=193c85ba-43c2-4be2-82cf-7b394a83390e

Amlodipine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 7 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a692044.html

DailyMed - Amlodipine - amlodipine tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 7 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1cec7a02-b7a5-49e1-ab64-3a4dab4149d2
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Information on this page was last updated on 23 Apr 2019

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