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Amide 400 MG Tablet

Manufactured byIcon Life Sciences
ContainsAmisulpride
Description
Amide 400 MG Tablet is an antipsychotic medicine used for the treatment of schizophrenia (a mental condition that is characterised by disturbed thinking, emotions, perception of reality, sense of self, and behaviour) in adults. It works by altering the action of a chemical substance called dopamine in the brain. Amide 400 MG Tablet may cause some side effects like dizziness, drowsiness, restlessness, nervousness, dry mouth, constipation, trouble sleeping, weight gain, etc. Consult your doctor if these side effects bother you for a long time or become severe. Amide 400 MG Tablet can be taken with or without food. Your doctor will determine the dose and duration of treatment based on your clinical condition. Take it every day at the same time for the ease of remembering. Avoid taking more than the prescribed dose as it may lead to side effects. Amide 400 MG Tablet is not recommended for use if you are allergic to it. This medicine should be used with caution if you have diabetes, seizures (fits), Parkinson's disease (a brain disorder that affects movement), or heart, liver, or kidney problems. Inform your doctor about all your ongoing medications to avoid undesired effects. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.

Side effects

Major & minor side effects for Amide 400 MG Tablet

  • Fever
  • Excessive sweating
  • Change in heart rate
  • Tremor
  • Excessive salivation
  • Constipation
  • Dry mouth
  • Weight gain
  • Missed menstrual periods
  • Dizziness
  • Drowsiness
  • Nausea or Vomiting

Uses of Amide 400 MG Tablet

What is it prescribed for?

  • Schizophrenia
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken by Amide 400 MG Tablet to show its effect is not clinically known.
  • How long do the effects of this medicine last?
    The amount of time for which Amide 400 MG Tablet remains active in your body is not clinically known.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consumption of alcohol during treatment with Amide 400 MG Tablet as it may increase the risk of side effects.
  • Is this a habit forming medicine?
    Amide 400 MG Tablet has no habit-forming tendency.
  • Can this medicine be taken during pregnancy?
    Amide 400 MG Tablet is not recommended for use during pregnancy as it may harm your foetus. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Amide 400 MG Tablet is unsafe for use while breastfeeding as this medicine passes into the breastmilk and may harm your baby. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Amide 400 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Phaeochromocytoma

Phaeochromocytoma is a rare tumour of the adrenal glands (a small gland located on top of your kidney that is responsible for producing chemical substances known as hormones). It is often associated with symptoms such as high blood pressure, increased heartbeat, sweating, headache, etc. Avoid taking Amide 400 MG Tablet if you have pheochromocytoma as it may result in a hypertensive crisis (a severe increase in blood pressure with a high risk of other complications that may be life-threatening).

Prolactin dependent tumour

Prolactin-dependent tumour is a tumour that develops due to an excess of prolactin hormone in the body. Women with higher blood levels of prolactin have a higher risk of breast cancer. Also, prolactinoma is a tumour of the pituitary gland (a gland at the base of the brain) that produces an excessive amount of the hormone prolactin. Amide 400 MG Tablet is not recommended for use if you have prolactinoma or breast cancer as it may further worsen your condition.

Levodopa

Levodopa is a medicine used in the treatment of Parkinson's disease (a brain disorder that affects movement with symptoms such as tremors, shakiness, stiffness, difficulty in walking, impaired balance and coordination, etc.). Combined use of Amide 400 MG Tablet and Levodopa is not recommended as the effects of these medicines are exactly the opposite. Thus it will reduce the effectiveness of both medications and also increase the risk of undesired effects.
Warnings for special population

Pregnancy

Amide 400 MG Tablet is not recommended for use during pregnancy as it may harm your foetus. Hence, consult your doctor if you are pregnant.

Breast-feeding

Amide 400 MG Tablet is unsafe for use while breastfeeding as this medicine passes into the breastmilk and may harm your baby. Hence, consult your doctor if you are breastfeeding.
General warnings

Heart disease

Amide 400 MG Tablet Tablet may cause a heart rhythm problem called QT prolongation and also increase the risk of formation of blood clots. Hence, this medicine should be used with caution if you have heart problems. Your doctor may suggest tests to monitor the functioning of your heart while you are taking this medicine.

Diabetes mellitus

Diabetes is a condition in which there is an increase in blood sugar levels. Amide 400 MG Tablet should be used with caution if you have diabetes as this medicine may alter your blood sugar levels. Monitor your blood sugar levels regularly during treatment with this medicine.

Hypokalaemia

Amide 400 MG Tablet should be used with caution if you have low potassium levels. Your doctor may initiate the treatment with this medicine only after the potassium deficit is corrected.

Use in the elderly

Amide 400 MG Tablet should be used with extreme caution in the elderly due to the increased risk of side effects.

Use in children

Amide 400 MG Tablet is not recommended for use in children below 18 years of age as the safety and efficacy data are not clinically established.

Seizure disorders

Seizure disorder is a neurological condition in which your brain activity becomes abnormal, causing uncontrolled jerking of the body. Amide 400 MG Tablet should be used with caution if you have seizures, as this medicine may trigger a seizure attack and worsen your condition.

Leukopenia

Leukopenia is a condition in which there is decreased white blood cell count characterised by frequent infections, fever with chills, sore throat, mouth ulcers, etc. Amide 400 MG Tablet should be use with caution as it may cause leukopenia. Consult your doctor immediately if you experience unexplained infections or fever.

Suicidal tendencies

Amide 400 MG Tablet may cause changes in mood and behaviour and suicidal thought, especially during the initial stage of the treatment. Inform your doctor immediately if you experience mood changes or develop thoughts of self-harm so that counselling can be done.

Driving or operating machines

Amide 400 MG Tablet may cause drowsiness, dizziness, or blurred vision in some cases. Hence, avoid performing activities such as driving vehicles or operating machines if you experience any of these symptoms during treatment with Amide 400 MG Tablet.

Parkinson's disease

Parkinson's disease is a brain disorder that affects movement. Amide 400 MG Tablet should be used with caution if you have Parkinson's disease as it may further worsen your condition.

Missed Dose

Take the missed dose of Amide 400 MG Tablet as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Contact your doctor in case of an overdose of Amide 400 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol during treatment with Amide 400 MG Tablet as it may increase the risk of side effects.
Interaction with Medicine

Diltiazem

Tramadol

Quinidine

Disease interactions

Kidney Disease

Amide 400 MG Tablet is excreted via the kidney and may get accumulated in your body if your kidneys are not functioning properly. This can increase the risk of side effects. Hence, this medicine should be used with caution if you have kidney problems.

Liver Disease

Amide 400 MG Tablet should be used with caution if you have liver problems as it may further worsen your condition. Consult your doctor immediately if you experience fatigue, loss of appetite, nausea, vomiting, abdominal pain, or yellow colouring of the eyes or skin.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Amide 400 MG Tablet exactly advised by your doctor. Do not break, chew, or crush the tablet. Do not take in larger or smaller amounts than prescribed. Consult your doctor if you experience any undesirable effects that persist or worsen Do not stop taking Amide 400 MG Tablet without consulting your doctor, as sudden discontinuation may cause withdrawal symptoms such as nausea, vomiting, and sleeping difficulty. Hence, your doctor will gradually reduce the dose over a period to avoid such undesired effects. Also, if you stop taking this medicine early, it may worsen your condition. Amide 400 MG Tablet may cause weight gain. Hence, monitor your weight periodically while you are taking this medicine. Inform your doctor if you have a history of breast cancer, as this medicine may increase the risk of breast cancer. Avoid driving vehicles or operating machines if you feel dizzy or drowsy after taking Amide 400 MG Tablet.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Amide 400 MG Tablet works by altering the action of a chemical substance called dopamine in the brain.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Atypical antipsychotics

Schedule

Schedule H

Medicines.org.uk. 2022. [online] Available at: < [Accessed 17 February 2022].

https://www.medicines.org.uk/emc/files/pil.548.pdf>

Medsafe.govt.nz. 2022. [online] Available at: < [Accessed 17 February 2022].

https://www.medsafe.govt.nz/Consumers/CMI/s/solian.pdf>

Medicines.org.uk. 2022. Amisulpride 200mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 25 February 2022].

https://www.medicines.org.uk/emc/product/3965/smpc#CLINICAL_PRECAUTIONS>
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Information on this page was last updated on 7 Jul 2022

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